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Mesalazine

Written By Dr. MayankReviewed By Dr. Rajeev Sharma
Last updated 25 Nov 2025 | 09:34 AM (UTC)

Mesalazine Uses

Mesalazine is used in the treatment of Ulcerative colitis and Crohn’s disease.

Available generics for Mesalazine

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How Mesalazine works

Mesalazine is an aminosalicylate. It works by suppressing the production of chemical messengers (prostaglandins) that cause inflammation (swelling) in the intestines. This reduces ulceration, bleeding and stomach pain, and prevents future flare-ups of the disease.

Common side effects of Mesalazine

Flatulence, Headache, Vomiting, Diarrhea, Nausea, Abdominal pain, Rash, Dyspepsia
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Expert advice for Mesalazine

  • You have been prescribed Mesalazine for treating and lowering the symptoms of mild inflammatory bowel disease such as ulcerative colitis.
  • Your doctor may monitor your kidney and liver functions before you start treatment with this medicine and regularly thereafter. Inform your doctor if you have severely decreased kidney or liver function.
  • Do not take Mesalazine if you are allergic to aspirin or if you have blood disorders.
  • Do not stop taking the medication suddenly without talking to your doctor.
  • You have been prescribed Mesalazine for treating and lowering the symptoms of mild inflammatory bowel disease such as ulcerative colitis.
  • Take it with food. Do not break, chew, or crush the tablets or granules. Swallow them whole with plenty of water.
  • Do not take antacids with Mesalazine as it can make your inflammation worse.
  • Your doctor may monitor your kidney and liver functions before you start treatment with this medicine and regularly thereafter. Inform your doctor if you have severely decreased kidney or liver function.
  • Do not take Mesalazine if you are allergic to aspirin or if you have blood disorders.

Frequently asked questions for Mesalazine

Continue to take Mesalazine as advised by the doctor, even if you feel better at the beginning of your treatment. Do not stop taking Mesalazine without consulting your doctor.
Mesalazine is used for the treatment of ulcerative colitis, however, you should not start taking the medicine on your own. Consult a doctor who will prescribe you the right dose and duration of treatment and will address any related or other concerns that you have.
You should avoid alcohol if you have ulcerative colitis, as alcohol will irritate your stomach and intestine which will worsen your condition. Although alcohol does not interfere with the working of Mesalazine, you should consult your doctor before taking alcohol.
Yes, Mesalazine may cause joint pain. If the pain continues and bothers you inform your doctor.