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Mesalazine is used in the treatment of ulcerative colitis and crohn’s disease.

How it works

Mesalazine blocks the release of chemical messengers that cause inflammation of the lining of the intestines.

Common side effects

Nausea, Headache, Diarrhoea, Abdominal pain

Available Medicine

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Expert advice

  • Do not take the medicine if you are allergic to mesalazine, to any other content in the medicine, aspirin and other salicylate drugs.
  • Do not take mesalazine if you have severe kidney or liver problems, blood disorders or uncontrolled bleeding.
  • Do not take mesalazine if you have stomach or bowel ulcers or a history of bleeding ulcers, glucose-galactose mala absorption, Lapp-lactase deficiency or galactose intolerance.
  • Doctor’s advice should be considered in case of patients with liver, kidney or lung disease (asthma).
  • Avoid taking mesalazine if you are pregnant or planning to become pregnant or breast-feeding.

Frequently asked questions



Is mesalazine a steroid, NSAID, immunosuppressant, blood-thinner or sulfa drug?
Mesalazine is not a steroid, NSAID, immunosuppressant, blood-thinner or sulfa drug. It is an anti-inflammatory drug


Can I take mesalazine forever?
No. Mesalazine should only be taken for the duration prescribed by your doctor


Is mesalazine safe?
Yes. Mesalazine is relatively safe if used as recommended. In case of any side-effects, consult your doctor

Show More

Can I take Asacol with Advil, Nyquil, tylenol, aspirin, Gaviscon, Imodium?
Asacol (mesalazine) can be taken with Nyquil, Tylenol (paracetamol), Gaviscon (sodium alginate) and Imodium (loperamide) only if prescribed by your doctor. It should not be taken with Advil (ibuprofen) or aspirin


Does mesalazine cause bleeding, weight gain, hair loss, immune suppression or liver problems?
Mesalazine may cause liver problems, immune suppression, hair loss, or bleeding. If you experience any such symptoms, please consult your doctor


Does mesalazine affect fertility or sperm count?
There is no evidence of mesalazine affecting fertility, but it may very rarely and reversibly reduce sperm count. If you experience any such problems, please consult your doctor.

Content on this page was last updated on 30 March, 2017, by Dr. Varun Gupta (MD Pharmacology)