Author Details
Written By
BDS
Reviewed By
MD (Pharmacology), MBBS
Last updated:
12 Sep 2020 | 06:15 PM (IST)
Want to know more?
Read Our Editorial Policy
Have issue with the content?
Report Problem

Mario 25mg Tablet

Prescription Required
Manufacturer
SALT COMPOSITION
Storage
Store at room temperature (10-30°C)

Introduction

Mario 25mg Tablet is a tricyclic antidepressant. It is used in adults to treat obsessive-compulsive disorder (OCD). It also treats muscular weakness (cataplexy) associated with repeat attacks of sleepiness (narcolepsy) and can manage depression that is unresponsive to other medicines.

Mario 25mg Tablet works by increasing the levels of chemical messengers in the brain that stabilizes and enhances the mood. It is better to take it before bedtime because it can make you feel sleepy. It can be taken with or without food, but you should take it at a fixed time each day for better efficacy. The dose and duration will be decided by your doctor so that you get the right amount to control your symptoms. If you have missed any dose, take it as soon as you remember. Do not skip any dose and finish the full course of treatment even if you feel better. This medication must not be stopped suddenly without talking to the doctor. Your dose may be modified or gradually decreased before stopping the medication.

The most common side effects of this medicine include indigestion, loss of appetite, dryness in the mouth, nausea, and constipation among others. It may also cause dizziness and drowsiness, do not drive or do anything that requires mental focus until you know how this medicine affects you. To lower the chances of dizziness, rise slowly if you have been sitting or lying down.  It may also lead to weight gain in some people. Most of the common side effects tend to be mild and temporary. Your doctor may be able to suggest ways of preventing or reducing side effects if they bother you or do not go away. Serious side effects associated with this medicine are rare.

Before taking this medicine, it is important to tell your doctor if you are taking or have recently taken any other medicines for the same or any other diseases. Pregnant and breastfeeding women should take this medicine with proper consultation and caution. This medicine is not addictive, but you can experience additional side effects (withdrawal symptoms) if you stop taking it suddenly. If you notice any sudden mood change or get suicidal or self-harm thoughts, you must consult the doctor without delay. Also, remember to take this medicine strictly as advised by the doctor as an overdose of this medication may lead to a serious health emergency.

Uses of Mario Tablet

Benefits of Mario Tablet

In Obsessive-compulsive disorder

Obsessive-compulsive disorder (OCD) is a disorder that affects mental health. People may develop a cycle of obsessions and compulsions, irrespective of age. Obsessions are unwanted, repeated thoughts, images, or urges that trigger excessively distressing feelings. Mario 25mg Tablet helps relieve symptoms of obsessive-compulsive disorder by increasing the level of a chemical called serotonin in your brain. It has fewer side effects than other medicines and is normally taken once a day. Keep taking the medicine until your doctor advises you to stop.

In Depression

Mario 25mg Tablet is thought to work by affecting the balance of certain chemicals (such as serotonin) in the brain. It helps improve mood and feelings of wellbeing, relieve anxiety and tension, help you sleep better, and increase your energy level. It is used to treat depression that is unresponsive to other medicines. You need to take it regularly as it is prescribed for it to be most effective and should not stop taking it suddenly.

Side effects of Mario Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Mario

  • Dryness in mouth
  • Constipation
  • Altered libido
  • Ejaculation disorder
  • Difficulty in urination
  • Dizziness
  • Fatigue
  • Impotence
  • Increased appetite
  • Indigestion
  • Loss of appetite
  • Muscle twitching
  • Sweating
  • Tremor
  • Weight gain
  • Drowsiness
  • Urinary incontinence
  • Nervousness
  • Visual disorder

How to use Mario Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Mario 25mg Tablet is to be taken with food.

How Mario Tablet works

Mario 25mg Tablet is a tricyclic antidepressant. It increases the levels of chemical messengers in the brain that help in regulating the mood and treat depression.

Safety Advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Mario 25mg Tablet.
Pregnancy
CONSULT YOUR DOCTOR
Mario 25mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breastfeeding
CONSULT YOUR DOCTOR
Mario 25mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Mario 25mg Tablet may cause side effects which could affect your ability to drive.
If you feel dizzy, tired, have blurred vision, have difficulty concentrating, or have other effects such as confusion, disorientation or your depression gets worse with Mario 25mg Tablet, do not drive.
Kidney
CONSULT YOUR DOCTOR
There is limited information available on the use of Mario 25mg Tablet in patients with kidney disease. Please consult your doctor.
Caution should be exercised in patients with underlying kidney disease. Regular monitoring of kidney function test is advised while you are taking this medicine.
Liver
CAUTION
Mario 25mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Mario 25mg Tablet may be needed. Please consult your doctor.
Regular monitoring of liver function tests is advisable when you are taking this medicine.

What if you forget to take Mario Tablet?

If you miss a dose of Mario 25mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Mario 25mg Tablet
₹3.8/Tablet
Clomine 25mg Tablet
Psychotropics India Ltd
₹2.0/Tablet
save 47%
₹5.84/Tablet
54% costlier
Clomidep 25mg Tablet
Triko Pharmaceuticals
₹5.94/Tablet
56% costlier
Clofranil 25mg Tablet
Sun Pharmaceutical Industries Ltd
₹6.19/Tablet
63% costlier
Clonil 25mg Tablet
Intas Pharmaceuticals Ltd
₹6.19/Tablet
63% costlier

Quick Tips

  • It may take 4 to 6 weeks for Mario 25mg Tablet to start working. Keep taking it as prescribed.
  • It may cause sleepiness. Take it at bedtime and do not drive or do anything requiring concentration until you know how it affects you.
  • Avoid consuming alcohol when taking Mario 25mg Tablet as it may cause excessive sleepiness.
  • Monitor your weight during the treatment as this medicine can cause weight gain and increased appetite.
  • Talk to your doctor if you notice sudden mood changes or develop suicidal thoughts.

Fact Box

Chemical Class
Dibenzoxepin Derivative
Habit Forming
No
Therapeutic Class
NEURO CNS

Interaction with Drugs

Taking Mario with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Lizolan, Lidoford, Mapzolide
LIFE-THREATENING
Brand(s): Trima, Rimarex, Morex
LIFE-THREATENING
Brand(s): Moxicheck, Moxonex, Unsym
LIFE-THREATENING

Patient Concerns

arrow
I have Obsessive compulsive Disorder. Prescribe the medication.
Dr. Deepak Kumar Soni
Ayurveda
Hi Kindly share your symptoms of your Problem
Sir, I wont to take best medicine of Ayurveda for obsessive compulsive disorders(Depression)
Dr. Ankur Kumar Tanwar
Ayurveda
Use brahmi granules and jatamansi vati ,
arrow
Do you have any questions related to Mario 25mg Tablet ?

FAQs

Q. Can Mario 25mg Tablet cause impotence?

Yes, Mario 25mg Tablet can cause impotence. Both men and women may experience decreased sexual desire and inability to have an organsm. In males, difficulty in maintaining erection (impotence) or painful ejaculation may be observed. You should consult your doctor immediately if you face any such problems while taking Mario 25mg Tablet.

Q. Is Mario 25mg Tablet safe?

Yes, Mario 25mg Tablet is safe to use if taken in the dose and duration prescribed by the doctor. Mario 25mg Tablet is a medicine that treats Obsessive-Compulsive Disorder (OCD), stabilises mood and behavior. It restores the chemical imbalance in the brain and creates a feeling of well being.

Q. What are the side effects of Mario 25mg Tablet?

Mario 25mg Tablet may cause side effects like difficulty or inability to pass urine, altered libido, constipation, dryness in mouth, ejaculation disorder, indigestion and sleepiness. Please consult your doctor if these side effects worry you. The doctor may suggest ways to treat or prevent them.

Q. What happens if I take an overdose of Mario 25mg Tablet?

If you have taken an overdose of Mario 25mg Tablet, you may experience symptoms such as drowsiness, restlessness, agitation and delirium (disturbed state of mind with restlessness and mental confusion). You may also experience severe sweating, fast heartbeat, feeling of faint, seizures (fits), and you may even go into a state of coma. Immediately consult your doctor and seek medical help if you think you have taken too much of this medicine.

Q. If I am feeling better, can I stop taking Mario 25mg Tablet?

No, do not stop taking Mario 25mg Tablet suddenly even if you are feeling better as it may worsen your condition and also cause withdrawal symptoms such as dizziness, nausea, vomiting, headache, weakness, sleep problems, fever, and irritability. Continue taking Mario 25mg Tablet for the duration as prescribed by your doctor to get maximum benefit. If any of the side effects are bothering you, consult your doctor. In case you have completed your course of treatment, your doctor will reduce your dose gradually before taking you off this medicine completely.

Related Products

Related Ayurvedic Ingredients

Want to share the information?

Disclaimer:

1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Stahl SM, editor. Clomipramine. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 129-35.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 298-300.
  3. Clomipramine hydrochloride. Whitby, Ontario, Canada: Patheon Inc.; [revised Jun. 2014]. [Accessed 22 Mar. 2019] (online) Available from:External Link
  4. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 20 Mar. 2019] (online) Available from:External Link
  5. Central Drugs Standard Control Organisation (CDSCO). [Accessed 22 Mar. 2019] (online) Available from:External Link

Manufacturer/Marketer Address

S.C.O-96, Level-II, Near Vatika, Sector-5, Panchkula -134109 India
Country of Origin: India

Best Price
₹32.3
MRP38  Get 15% OFF
Inclusive of all taxes
Best price is valid on orders above ₹499
10 tablets in 1 strip
SOLD OUT

INDIA’S LARGEST HEALTHCARE PLATFORM

150M+
Visitors
25M+
Orders Delivered
1000+
Cities
Get the link to download App
Reliable

All products displayed on 1mg are procured from verified and licensed pharmacies. All labs listed on the platform are accredited

Secure

1mg uses Secure Sockets Layer (SSL) 128-bit encryption and is Payment Card Industry Data Security Standard (PCI DSS) compliant

Affordable

Find affordable medicine substitutes, save up to 50% on health products, up to 80% off on lab tests and free doctor consultations.

India's only LegitScript and ISO/IEC 27001 certified online healthcare platform
Know More About 1mgdownArrow
Access medical and health information

1mg provides you with medical information which is curated, written and verified by experts, accurate and trustworthy. Our experts create high-quality content about medicines, diseases, lab investigations, Over-The-Counter (OTC) health products, Ayurvedic herbs/ingredients, and alternative remedies.

Order medicines online

Get free medicine home delivery in over 1000 cities across India. You can also order Ayurvedic, Homeopathic and other Over-The-Counter (OTC) health products. Your safety is our top priority. All products displayed on 1mg are procured from verified and licensed pharmacies.

Book lab tests

Book any lab tests and preventive health packages from certified labs and get tested from the comfort of your home. Enjoy free home sample collection, view reports online and consult a doctor online for free.

Consult a doctor online

Got a health query? Consult doctors online from the comfort of your home for free. Chat privately with our registered medical specialists to connect directly with verified doctors. Your privacy is guaranteed.