MRP:Rs. 66 for 1 strip(s) (10 tablet each)
Report Error


Clomipramine(25 mg)


Clomipramine(25 mg)


Clomipramine is used in adults to treat obsessive compulsive disorder (mental condition characterized by unwanted thoughts and repetitive behavior). It is also used to treat muscular weakness (cataplexy) associated with repeat attacks of extreme sleepiness (narcolepsy).

How it works

Clomipramine belongs to the group of medicines called tricyclic antidepressants. It acts by restoring the balance of chemical substances (serotonin) present in the brain.

Common side effects

Sexual activity disorder, Low blood pressure with change of position, Restlessness, Increased blood pressure, Itching of skin, Fatigue, Blurred vision, Hypomania, Activation of psychotic symptoms, Problems with erection, Heartbeat related disorder, Anaphylactic reactions including hypotension, Abnormal electroencephalogram, Speech disorder, Yawning, Unable to sleep, Siadh, Memory impairment, Neuroleptic malignant syndrome, Urinary retention, Increased pressure inside the eye causing visual problems, Acute confusional state, Disturbance in attention, Disorientation, Increase in liver enzymes, Vomiting, Abnormal milky discharge from the breasts, Involuntary muscle jerks, Pneumonitis with or without eosinophilia, Sensitivity to sunlight, Breast enlargement, Abdominal disorders, Aggravation of depression, Increased appetite, Abnormally high fever, Abnormal sensations of skin, Aggression, Loose motions, Muscular weakness, Ringing in ears, Hepatitis with or without jaundice, Skin allergies, Dizziness, Sleepiness, Anxiety, Bleeding vessels near the skin surface, Uncontrolled shaking, Depersonalisation, Most, Abnormal increase in sweating, Dilatation of the pupil of the eye, Hair loss, Fits, Unpleasant dreams, Muscle Hypertonia, Hot flush, Thumping, Abnormal ECG changes, Swelling, Seeing or hearing things that are not really there, Reddish-purple discoloration of skin due to small, Pounding or fluttering sensation in chest, Increased weight, Sleep disorder, Agitation, Decreased appetite, Headache, Problem in passing urine, Unsteady movement, Altered taste sensation, Mania


16 Substitutes
Sorted By
    (10 tablet in strip)
    Intas Pharmaceuticals Ltd
    Rs. 6.25/tablet
    Rs. 62.50
    save 5% more per tablet
    (10 tablet in strip)
    Talent Healthcare
    Rs. 5.04/tablet
    Rs. 50.40
    save 24% more per tablet
    (10 tablet in strip)
    La Pharmaceuticals
    Rs. 5.17/tablet
    Rs. 51.70
    save 22% more per tablet
    (10 tablet in strip)
    Triko Pharmaceuticals
    Rs. 4.70/tablet
    Rs. 47
    save 29% more per tablet
    (10 tablet in strip)
    Psychotropics India Ltd
    Rs. 2/tablet
    Rs. 20.02
    save 70% more per tablet

Expert advice

  • Do not start or continue clomipramine tablets, if you are allergic (hypersensitive) to tricyclic antidepressants, clomipramine or any of the other ingredients of clomipramine medication.
  • Do not take clomipramine if you have history of suicide-related events.
  • Avoid using clomipramine if you are pregnant or breast feeding.
  • Advice care givers to monitor the patient carefully.
  • Doctor’s advice should be considered in case of following disease conditions: heart disorders, serotonin syndrome, fits (convulsions), increased pressure inside the eye causing visual problems (narrow angle glaucoma), urinary retention, liver disease, and chronic constipation.

Frequently asked questions


Q. Is clomipramine safe?
Clomipramine is safe if used at prescribed dose and duration as advised by your doctor.

Q. Is clomipramine a MAOI/anticholinergic/benzodiazepine/SSRI/narcotic?
Clomipramine is tricyclic antidepressant. It treats depression through inhibiting the neuronal re-uptake of chemical substances present in the brain called noradrenaline and mainly serotonin (SSRI). It is not MAOI/anticholinergic/benzodiazepine/narcotic.

Q. Is clomipramine a controlled substance?
No, it is not a controlled substance.

Q. Is clomipramine addictive?
Clomipramine is not addictive if used at prescribed dose and duration as advised by your doctor.

Q. Can I take paracetamol/diazepam/5htp with clomipramine?
Taking other medicines may alter the effects of clomipramine. Always consult your doctor for the change of dose regimen or an alternative drug of choice that may strictly be required.

Q. Does clomipramine cause weight loss/weight gain/make you sleepy/cause constipation/affect fertility?
Clomipramine may cause these side effects; effect on fertility is very rare side effect. However, consult your doctor if you experience any of these side effects.

Q. Does clomipramine help premature ejaculation?
Clomipramine effectively increases ejaculatory latency in men with primary premature ejaculation, while treatment is not effective in those with premature ejaculation and erectile dysfunction.

Q. Does clomipramine work for obsessive-compulsive disorder (OCD)?
Yes, clomipramine is used for obsessive-compulsive disorder. Patients should follow the advice of the doctor regarding its use.