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    Information about Clomipramine

    Clomipramine uses

    Clomipramine is used in adults to treat obsessive compulsive disorder (mental condition characterized by unwanted thoughts and repetitive behavior). It is also used to treat muscular weakness (cataplexy) associated with repeat attacks of extreme sleepiness (narcolepsy).
    . It is used in patients intolerant of or unresponsive to alternative treatment options for depression.

    How clomipramine works

    Clomipramine increases the levels of chemical messengers in the brain that help in regulating the mood and treat depression.

    Common side effects of clomipramine

    Dryness in mouth, Difficulty in urination, Constipation, Orthostatic hypotension (sudden lowering of blood pressure on standing), Weight gain, Increased heart rate
    Content Details
    Written By
    Dr. Swati Mishra
    Reviewed By
    Dr. Ashish Ranjan
    MD (Pharmacology), MBBS
    Last updated on:
    01 Aug 2019 | 11:57 AM (IST)
    Want to know more?
    Read Our Editorial Policy

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    Frequently asked questions for Clomipramine


    Q. Is Clomipramine safe?

    Clomipramine is safe if used at prescribed dose and duration as advised by your doctor

    Q. Is Clomipramine a MAOI/anticholinergic/benzodiazepine/SSRI/narcotic?

    Clomipramine is tricyclic antidepressant. It treats depression through inhibiting the neuronal re-uptake of chemical substances present in the brain called noradrenaline and mainly serotonin (SSRI). It is not MAOI/anticholinergic/benzodiazepine/narcotic

    Q. Is Clomipramine a controlled substance?

    No, it is not a controlled substance

    Q. Is Clomipramine addictive?

    Clomipramine is not addictive if used at prescribed dose and duration as advised by your doctor

    Q. Can I take paracetamol/diazepam/5htp with clomipramine?

    Taking other medicines may alter the effects of clomipramine. Always consult your doctor for the change of dose regimen or an alternative drug of choice that may strictly be required

    Q. Does Clomipramine cause weight loss/weight gain/make you sleepy/cause constipation/affect fertility?

    Clomipramine may cause these side effects; effect on fertility is very rare side effect. However, consult your doctor if you experience any of these side effects

    Q. Does Clomipramine help premature ejaculation?

    Clomipramine effectively increases ejaculatory latency in men with primary premature ejaculation, while treatment is not effective in those with premature ejaculation and erectile dysfunction

    Q. Does Clomipramine work for obsessive-compulsive disorder (OCD)?

    Yes, Clomipramine is used for obsessive-compulsive disorder. Patients should follow the advice of the doctor regarding its use.

    Content on this page was last updated on 01 August, 2019, by Dr. Varun Gupta (MD Pharmacology)