Madrazine OD 1200mg Tablet PR is an anti-inflammatory medicine used to treat a type of bowel disease known as ulcerative colitis. It helps to reduce symptoms such as diarrhea, bleeding and stomach pain by reducing inflammation in the bowel.

Madrazine OD 1200mg Tablet PR may also be used to treat another type of bowel disease known as Crohn’s ileocolitis. It should be taken with food. The dose will depend on what you are being treated for but take it exactly as your doctor prescribes. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen.

The most common side effects of this medicine include nausea, diarrhea, stomach pain, headache, itching, flatulence, and vomiting. If these symptoms bother you, do not go away, or get worse, let your doctor know. There may be ways of reducing or preventing them. Some people may get a severe allergic reaction that needs urgent medical attention. Contact your doctor immediately if you notice symptoms like swelling of the face, tongue, throat, or lips, unusual bleeding, bruising, rash, fever, sore throat, or excessive tiredness.

Before taking it, tell your doctor if you have any kidney or liver problems or a blockage in your stomach. Your age may also be a factor in deciding whether this medicine is suitable. Pregnant or breastfeeding women should also consult their doctor before taking this medicine. Let your doctor know about all other medications you are taking as some may affect, or be affected by this medicine.

Uses of Madrazine OD Tablet PR

Side effects of Madrazine OD Tablet PR

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Madrazine OD

Stomach pain/epigastric pain
Flatulence
Headache
Vomiting
Diarrhea
Nausea
Abdominal pain
Rash

How to use Madrazine OD Tablet PR

Use it as advised by your doctor or check the label for directions before use. Madrazine OD 1200mg Tablet PR may be taken with or without food, but it is better to take it at a fixed time.

How Madrazine OD Tablet PR works

Madrazine OD 1200mg Tablet PR is an aminosalicylate. It works by suppressing the production of chemical messengers (prostaglandins) that cause inflammation (swelling) in the intestines. This reduces ulceration, bleeding and stomach pain, and prevents future flare-ups of the disease.

Safety advice

Alcohol

CAUTION

Caution is advised when consuming alcohol with Madrazine OD 1200mg Tablet PR. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Madrazine OD 1200mg Tablet PR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Madrazine OD 1200mg Tablet PR is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
If you are taking Madrazine OD 1200mg Tablet PR, monitor the baby for diarrhea.

Driving

SAFE

Madrazine OD 1200mg Tablet PR does not usually affect your ability to drive.

Kidney

CAUTION

Madrazine OD 1200mg Tablet PR should be used with caution in patients with kidney disease. Dose adjustment of Madrazine OD 1200mg Tablet PR may be needed. Please consult your doctor.
Use of Madrazine OD 1200mg Tablet PR is not recommended in patients with severe kidney disease.

Liver

CAUTION

Madrazine OD 1200mg Tablet PR should be used with caution in patients with liver disease. Dose adjustment of Madrazine OD 1200mg Tablet PR may be needed. Please consult your doctor.

What if you forget to take Madrazine OD Tablet PR?

If you miss a dose of Madrazine OD 1200mg Tablet PR, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.\n

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Madrazine OD 1200mg Tablet PR

₹29.3/Tablet PR

Coolgut Tablet PR

Torrent Pharmaceuticals Ltd

₹42.9/tablet pr

46% costlier

Mesahenz 1200 Tablet PR

La Renon Healthcare Pvt Ltd

₹24.7/tablet pr

16% cheaper

Mesarem 1200 Tablet PR

Hetero Healthcare Limited

₹30.8/tablet pr

5% costlier

Mesacol OD Tablet PR

Sun Pharmaceutical Industries Ltd

₹37.13/tablet pr

27% costlier

Vegaz OD Tablet PR

Dr Reddy's Laboratories Ltd

₹47.87/tablet pr

63% costlier

View all substitutes

Quick tips

You have been prescribed Madrazine OD 1200mg Tablet PR for treating and lowering the symptoms of mild inflammatory bowel disease such as ulcerative colitis.
Your doctor may monitor your kidney and liver functions before you start treatment with this medicine and regularly thereafter. Inform your doctor if you have severely decreased kidney or liver function.
Do not take Madrazine OD 1200mg Tablet PR if you are allergic to aspirin or if you have blood disorders.
Do not stop taking the medication suddenly without talking to your doctor.
You have been prescribed Madrazine OD 1200mg Tablet PR for treating and lowering the symptoms of mild inflammatory bowel disease such as ulcerative colitis.
Take it with food. Do not break, chew, or crush the tablets or granules. Swallow them whole with plenty of water.
Do not take antacids with Madrazine OD 1200mg Tablet PR as it can make your inflammation worse.
Your doctor may monitor your kidney and liver functions before you start treatment with this medicine and regularly thereafter. Inform your doctor if you have severely decreased kidney or liver function.
Do not take Madrazine OD 1200mg Tablet PR if you are allergic to aspirin or if you have blood disorders.

Fact Box

Chemical Class

Aminosalicylic Acids Derivative

Habit Forming

Therapeutic Class

GASTRO INTESTINAL

Action Class

5-Aminosalicylic Acid (5-ASA)

Interaction with drugs

Taking Madrazine OD with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Clozapine (Oral Route) Moderate

Concurrent use may increase the risk of low blood cell counts. Your doctor may monitor your blood cell count and adjust the doses as per the observations.

Azathioprine (Oral Route) Moderate

Concurrent use may increase the risk for blood disorders, bone marrow failure, and associated complications. If concurrent use can not be avoided, your doctor may monitor your blo... More

Deferiprone (Oral Route) Moderate

Concurrent use may increase the risk of fall in white blood cell count. If concurrent use can not be avoided, your doctor may monitor your blood cell counts.

Mercaptopurine (Oral Route) Moderate

Concurrent use may increase the risk for blood disorders, bone marrow failure, and associated complications. If concurrent use can not be avoided, your doctor may monitor your blo... More

Chlorpromazine (Oral Route) Mild

Concurrent use may cause a severe drop in granulocyte (a type of white blood cell) count. Talk to your doctor if you notice any unusual symptoms.

View all drug interactions

Patient concerns

Suffering from ultratics colitis i have done colonoscopy test 04 months back From 05 months how many months I have to take medicines is it cure completely

Dr. Kunal Parasar

Surgical Gastroenterology

Ulcerative colitis is a lifelong disease with remission and exacerbations. Durations of remission cant b predicted all d time

Hi, I was diagnosed for Ulcerative Colitis in 2009. I was administered with Mesacol , I was back to normal. In past 1 month , after having food lunch or dinner I feel uneasy such as indigestion, having to force for motions next day. Sometimes Iam unable to pass motions. I feel tired also. Pls suggest.

Dr. Kunal Parasar

Surgical Gastroenterology

Ulcerative colitis is a lifong disease q with remission and exacerbation . U should b under constant follow up of ur gastroenterologist

FAQs

My symptoms have improved can I stop taking Madrazine OD 1200mg Tablet PR?

Continue to take Madrazine OD 1200mg Tablet PR as advised by the doctor, even if you feel better at the beginning of your treatment. Do not stop taking Madrazine OD 1200mg Tablet PR without consulting your doctor.

Can I drink alcohol while taking Madrazine OD 1200mg Tablet PR?

You should avoid alcohol if you have ulcerative colitis, as alcohol will irritate your stomach and intestine which will worsen your condition. Although alcohol does not interfere with the working of Madrazine OD 1200mg Tablet PR, you should consult your doctor before taking alcohol.

Does Madrazine OD 1200mg Tablet PR cause joint pain?

Yes, Madrazine OD 1200mg Tablet PR may cause joint pain. If the pain continues and bothers you inform your doctor.

When is the best time to take Madrazine OD 1200mg Tablet PR?

Take Madrazine OD 1200mg Tablet PR exactly as directed by your doctor.

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References

Mesalazine/Mesalamine. Milan, Italy: Cosmo S.p.A.; 1987 [revised date]. [Accessed on 28 Mar. 2018] (online) Available from:
Mesalamine. Weiterstadt Germany: Warner Chilcott Deutschland GmbH; [revised May 2010]. [Accessed 28 Mar. 2019] (online) Available from:
Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Mesalamine. [Updated 2019 Apr 1]. [Accessed 20 Feb. 2020] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 28 Mar. 2019] (online) Available from:
National Health Service. Mesalazine. [Last Reviewed: 19 Jul. 2021]. [Accessed 11 Jul. 2023]. (online) Available from:
Mesalazine [Package Insert]. Saint-Prex, Switzerland: Ferring International Center SA. [Accessed 11 Jul. 2023]. (online) Available from:

Marketer details

Name: Syntonic Lifesciences

Address: Syntonic Life Sciences, Shri Sai Market, Opposite Hotel Marc Royale Kalka- Zirakpur Highway, Dhakoli, Zirakpur-140603, Punjab, India

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.