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Istavel 25mg Tablet

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Product introduction

Istavel 25mg Tablet is a medicine used to treat type 2 diabetes mellitus. It is used together with a healthy diet and regular exercise to control blood sugar levels. This helps to prevent serious complications of diabetes like kidney damage and blindness.

Istavel 25mg Tablet is normally prescribed when diet and exercise alone or other medicines do not prove sufficient to control your blood sugar level. Your doctor may prescribe it alone or along with other diabetes medicines. It may be taken on an empty stomach or with a meal. The dose will depend on your condition, and blood sugar levels. Therefore, you should use it as advised by your doctor.

You should take it regularly at the same time each day to get the most benefit, and you should not stop unless your doctor recommends it. This medicine is helping you to control your blood sugar levels and prevent serious complications in the future. It is important to stay on the diet and exercise program recommended by your doctor while taking this medicine. Your lifestyle plays a big part in controlling diabetes.

The most common side effect of taking this medicine is a headache. This is usually minor and improves with time. Low blood sugar level (hypoglycemia) is a possible side effect if you are also taking other diabetes medicines like insulin or sulfonylurea, so you need to know how to recognize and deal with it. It may also cause upper respiratory tract infections like sore throat, cough, and cold. Contact your doctor if the side effects worry you or if they do not go away.

Before taking this medicine, let your doctor know if you have ever had kidney disease, heart or pancreas problems, or if you drink a lot of alcohol. Pregnant or breastfeeding women should also consult their doctor before taking it. Some other medicines you are taking may interfere with this medicine's working. So, make sure your doctor knows about all the other medicines you are using. Limit your alcohol intake while taking this medicine because it can increase your risk of developing low blood sugar levels. You may need regular tests such as kidney function and blood glucose levels to check that the medicine is working properly.

Benefits of Istavel Tablet

In Treatment of Type 2 diabetes mellitus

Istavel 25mg Tablet belongs to a group of medicines called DPP-4 inhibitors (or gliptins). It works by helping to increase the amount of insulin your body produces after a meal and to stop your body from releasing too much glucose (sugar) into your blood. The effect is to lower blood glucose levels. This medicine is usually taken once a day, has relatively few common side effects, and does not usually make you put on weight.

Lowering blood glucose levels is an essential part of managing diabetes. If you can control the level you will reduce the risk of getting any of the serious complications of diabetes such as kidney damage, eye damage, nerve problems, and loss of limbs. Proper control of diabetes can also reduce the risk of heart disease and stroke. Taking this medicine regularly along with a proper program of diet and exercise will help you live a normal, healthy life. You should keep using it for as long as it is prescribed because it is protecting your future health.

Side effects of Istavel Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Istavel

  • Nasopharyngitis (inflammation of the throat and nasal passages)
  • Headache
  • Hypoglycemia (low blood glucose level)

How to use Istavel Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Istavel 25mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Istavel Tablet works

Istavel 25mg Tablet is an antidiabetic medication. It works by increasing the release of insulin from the pancreas and decreasing the hormones that raise blood sugar levels. This reduces the fasting and postmeal sugar levels.

Safety advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Istavel 25mg Tablet.
Pregnancy
CONSULT YOUR DOCTOR
Information regarding the use of Istavel 25mg Tablet during pregnancy is not available. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Istavel 25mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
CAUTION
Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.
Kidney
CAUTION
Istavel 25mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Istavel 25mg Tablet may be needed. Please consult your doctor.
Liver
SAFE IF PRESCRIBED
Istavel 25mg Tablet is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Istavel 25mg Tablet may not be needed in these patients. Please consult your doctor.
However, Istavel 25mg Tablet has not been studied in patients with severe hepatic impairment and is not recommended for use in such patients.

What if you forget to take Istavel Tablet?

If you miss a dose of Istavel 25mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Istavel 25mg Tablet
₹6.64/Tablet
Januvia 25mg Tablet
MSD Pharmaceuticals Pvt Ltd
₹34.57/tablet
421% costlier
Sitapride 25mg Tablet
Micro Labs Ltd
₹7.67/tablet
16% costlier
Stalix 25 Tablet
Torrent Pharmaceuticals Ltd
₹10.6/tablet
60% costlier
Suitglip 25 Tablet
Ipca Laboratories Ltd
₹6.3/tablet
5% cheaper
Sitalembic 25mg Tablet
Alembic Pharmaceuticals Ltd
₹8.4/tablet
27% costlier

Quick tips

  • Istavel 25mg Tablet should be taken at the same time every day since this helps you remember to take it.
  • It may cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal.
  • Always carry some sugary food or fruit juice with you in case you experience hypoglycemia symptoms such as cold sweats, cool pale skin, tremor and anxiety.
  • Be careful while driving or operating machinery until you know how Istavel 25mg Tablet affects you.
  • Inform your doctor if you notice joint pains or develop symptoms such as stomach pain, nausea and/or vomiting.

Fact Box

Chemical Class
Pyrazine-derivative
Habit Forming
No
Therapeutic Class
ANTI DIABETIC
Action Class
DPP-4 inhibitors

Interaction with drugs

Taking Istavel with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Amiur
Serious
Brand(s): Becoride, Rhinase, Bevent
Serious
Brand(s): Densol, Catrisol, Betaforte
Serious
Brand(s): Chlornol
Serious

Patient concerns

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Diabetes mellitus type 2 ,thirst
Dr. Sanjay Bhatt
Physician
A person can control his or her sugar levels by doing regular exercise and walk or regular aerobic exercises at least 30 to 45 minutes per day.MEDICAL NUTRITIONAL THERAPY THAT IS TO MAINTAIN CALORIES INTAKE AS PER BMI .TAKE HELP OF DIABETIC EDUCATOR. VISIT YOUR DOCTOR AND FOLLOW ALL WHAT DOCTOR SUGGESTED.IN TIME ALL ROUTINE INVESTIGATIONS SHOULD BE DONE.you should not treat it as disease but a start of a healthy life.Uncontrolled sugar levels for long time leads to lower limb weakness which is neuropathy and which is followed by foot ulcers and other complications like kidney or heart problems .online prescription is not allowed without seeing pt.so contact doctor nearby for any change or dose adjustment or visit my clinic at gurgaon sector 52 RdCity snergy multi speciality clinic near SRS MARKET
Diabetes mellitus type 2 required only ayurvedic medicine
Dr. Sanjay Bhatt
Physician
Go for allopathic medicine
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User feedback


FAQs

Q. Does Istavel 25mg Tablet cause weight gain?

No, Istavel 25mg Tablet is not known to cause weight gain by itself. However, keeping a healthy weight is an important part of managing diabetes. Consult your doctor if you experience weight gain while taking Istavel 25mg Tablet.

Q. Is Istavel 25mg Tablet bad for your kidneys?

No, Istavel 25mg Tablet is not bad for your kidneys if your kidney function is normal. However, it is important to inform your doctor if you have, or ever had, any kidney problems. If you have kidney problems, you may need dose modification.

Q. Do I still have to manage my diet and exercise while on Istavel 25mg Tablet?

Yes, it is important to manage your diet and exercise while taking Istavel 25mg Tablet. In addition to medicine, making healthy food choices and being physically active are also important to effectively manage blood sugar levels. You may consult a dietitian and follow a diet chart that suits you best. A well-balanced diet is one part of a healthy lifestyle for people with type 2 diabetes. Additionally, thirty minutes of exercise such as a brisk walk is recommended.

Q. Can my blood sugar levels go too low on Istavel 25mg Tablet?

Yes, it is possible that your blood sugar levels may become very low (hypoglycemia). The chances are higher if you are on any other antidiabetic medicine or insulin along with Istavel 25mg Tablet. Additionally, blood sugar levels can take a huge dip if you skip meals, exercise more than usual, or if you have taken an overdose of Istavel 25mg Tablet. If you experience a sudden fall in your sugar levels, inform your doctor. The doctor may suggest dose modification to prevent your blood sugar levels from decreasing significantly (hypoglycemia). Follow your doctor’s advice and monitor your blood sugar levels regularly.

Q. What will happen if I accidentally take more than the prescribed dose of Istavel 25mg Tablet?

If you have accidentally taken more than the prescribed dose of Istavel 25mg Tablet, your blood sugar levels may become too low (hypoglycemia). This hypoglycemia may be mild or severe. Monitor your blood sugar levels more frequently for the next 24 hours. Mild episodes of hypoglycemia (with symptoms like anxiety, sweating, weakness, tremors, fast heartbeat) can usually be corrected with the help of sugary foods such as sugar or glucose candy, fruit juice and glucose/glucon-D. However, it is important to consult your doctor to decide the further course of treatment. More severe episodes of hypoglycemia may even lead to a seizure (fit) or unconsciousness. This can be life-threatening and immediate medical help may be required.

Q. What if I miss a dose of Istavel 25mg Tablet?

If you miss a dose, take it as soon as you remember. If in case you do not remember until it is time for your next dose, skip the missed dose and go back to your regular schedule. Do not take two doses of Istavel 25mg Tablet at the same time.

Q. Is Istavel 25mg Tablet safe to be taken for a long term?

Yes, it is safe to take Istavel 25mg Tablet for a long time. Its long-term use, which can continue for months, years or even lifelong, has not shown any harmful effects. Keep taking Istavel 25mg Tablet as long as your doctor recommends it. Remember, Istavel 25mg Tablet only helps to keep your blood sugar levels under control but does not cure your diabetes.

Q. How long do I need to take Istavel 25mg Tablet?

Istavel 25mg Tablet only helps to manage your blood sugar levels but does not cure your diabetes. Keep taking Istavel 25mg Tablet as long as your doctor recommends it. You may have to take it lifelong. It is important to keep your blood sugar levels under control as any fluctuations in your blood sugar levels may cause serious problems. Therefore, do not stop taking it without talking to your doctor.

Q. What is the most important information I should know about Istavel 25mg Tablet?

Istavel 25mg Tablet is safe to use if taken in the dose and duration prescribed by the doctor. However, in rare cases, some serious side effects can also be observed. In some people, Istavel 25mg Tablet may cause inflammation of the pancreas (pancreatitis) which could be severe and can even lead to death. If you experience severe and persistent pain in your stomach area (abdomen), stop the medication and immediately contact your doctor. Istavel 25mg Tablet can also cause heart failure. This means the heart is not able to pump blood well enough, therefore, inform your doctor if you have or ever had heart problems before you start taking Istavel 25mg Tablet. In addition to that, problems related to kidneys should also be discussed with the doctor.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Powers AC, D’Alessio D. Endocrine Pancreas and Pharmacotherapy of Diabetes Mellitus and Hypoglycemia. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1264-65.
  2. Nolte MS. Pancreatic hormones and antidiabetic drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 45.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1268-69.
  4. Sitagliptin. Pavia, Italy: Merck Sharp & Dohme (Italia) S.p.A.; 2006 [revised 2010]. [Accessed 12 Mar. 2019] (online) Available from:External Link
  5. Sitagliptin [Product Monograph]. Kirkland, Canada: Merck Canada Inc.; 2021. [Accessed 8 Oct. 2021] (online) Available from:External Link
  6. Sitagliptin [FDA Label]. Northumberland, UK. Merck Sharp & Dohme Ltd.; 2012. [Accessed 8 Oct. 2021] (online) Available from:External Link
  7. Sitagliptin [Product Information]. [Accessed 8 Oct. 2021] (online) Available from:External Link
  8. Sitagliptin [Package Insert]. Gangtok, Sikkim: Torrent Pharmaceuticals Ltd.; 2022. [Accessed 06 Aug. 2023]. (online) Available from:External Link

Marketer details

Name: Sun Pharmaceutical Industries Ltd
Address: Plot no 107/108,Namli block , Ranipool, East Sikkim 737135
Country of origin: India

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