Chlorthalidone

Last updated 25 Nov 2025 | 09:34 AM (UTC)

Chlorthalidone Uses

Chlorthalidone is used for Hypertension (high blood pressure), Heart Failure, kidney stone and Edema. It treats oedema (fluid overload) associated with heart, liver, kidney or lung disease.

How Chlorthalidone works

Chlorthalidone is a diuretic which lowers blood pressure by removing extra water and certain electrolytes from the body. Over time it also relaxes blood vessels and improves blood flow.

Common side effects of Chlorthalidone

Headache, Nausea, Vomiting, Dizziness, Vertigo, Orthostatic hypotension (sudden lowering of blood pressure on standing)

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Medicine brands for Chlorthalidone

CTD

Ipca Laboratories Ltd

₹116 to ₹149

2 variant(s)

Thaloric

Zuventus Healthcare Ltd

₹67 to ₹86

2 variant(s)

Thiaklor

Emcure Pharmaceuticals Ltd

₹43 to ₹50

2 variant(s)

Aquiris

Akumentis Healthcare Ltd

₹56 to ₹79

2 variant(s)

New CH

Systopic Laboratories Pvt Ltd

₹16 to ₹25

2 variant(s)

Chlorfid

Fidelity Lifesciences Pvt Ltd

₹39 to ₹46

2 variant(s)

Thiovas

Lakshya Life Sciences

₹47 to ₹54

2 variant(s)

Zione

Torrent Pharmaceuticals Ltd

₹39 to ₹39

1 variant(s)

Chlohat

Akesiss Pharma Pvt Ltd

₹31 to ₹31

1 variant(s)

Thalidon

Johnlee Pharmaceuticals Pvt Ltd

₹37 to ₹46

2 variant(s)

Expert advice for Chlorthalidone

Take it in the morning with breakfast to avoid getting up at night to urinate.
It makes you feel dizzy. Avoid driving and attention requiring activity until you know how it affects you.
Avoid alcohol intake while taking Chlorthalidone as it may increase the dizziness.
It may cause a sudden drop of sodium level in blood. Avoid low sodium diet while you are taking this medication.
Monitor your blood pressure after starting Chlorthalidone, and notify your doctor if it does not lower down.
Notify your doctor if you experience dizziness, tiredness, or muscle weakness that does not go away.
Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
Chlorthalidone helps lower blood pressure and also removes excess water from your body.
Take it in the morning with breakfast to avoid getting up at night to urinate.
It may cause dizziness in the initial days of treatment.
Monitor your blood pressure after starting Chlorthalidone, and notify your doctor if it does not lower down.
Notify your doctor if you experience dizziness, tiredness, or muscle weakness that does not go away.
You may be asked to get regular blood tests done to monitor your kidney function.
It makes you feel dizzy. Avoid driving and attention requiring activity until you know how it affects you.
Avoid alcohol intake while taking Chlorthalidone as it may increase the dizziness.
It may cause a sudden drop of sodium level in blood. Avoid low sodium diet while you are taking this medication.
Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

Frequently asked questions for Chlorthalidone

Q. Can I drink alcohol while taking Chlorthalidone?

No, do not take alcohol while on treatment with Chlorthalidone. Taking alcohol with Chlorthalidone may lower your blood pressure suddenly making you feel dizzy and lightheaded.

Q. What happens if I take more than the recommended dose of Chlorthalidone?

If you take more than the prescribed dose of Chlorthalidone, you may experience nausea, lightheadedness, weakness, fast or irregular heart beat, sleepiness, muscle cramps and pain, difficulty in breathing. Taking this medicine in high doses may even cause a heart attack. In a situation like this, contact your doctor immediately or seek emergency help in a nearby hospital.

Q. Can I take ibuprofen with Chlorthalidone?

This combination is best avoided since the two medicines may interfere with each other. However, if your doctor advises you to take both ibuprofen and Chlorthalidone, you will need to keep a regular check on your blood pressure and also monitor your kidney function tests.

Q. Does Chlorthalidone increase uric acid? Can it cause gout?

Yes, Chlorthalidone may raise uric acid levels. However, the occurrence of gout due to Chlorthalidone is very rare.

Q. Does Chlorthalidone cause skin cancer?

No, there have been no reports of Chlorthalidone causing skin cancer. However, in rare cases, this medicine can make the skin more sensitive to sunlight than usual. If you are exposed to direct sunlight you may get skin rash, so wear protective clothing and use sunscreen.