Information about Chlorthalidone

Chlorthalidone Uses

Chlorthalidone is used for Hypertension (high blood pressure). It treats oedema (fluid overload) associated with heart, liver, kidney or lung disease.

How Chlorthalidone works

Chlorthalidone is a diuretic which lowers blood pressure by removing extra water and certain electrolytes from the body. Over time it also relaxes blood vessels and improves blood flow.

Common side effects of Chlorthalidone

Headache, Nausea, Increased blood uric acid, Decreased potassium level in blood, Glucose intolerance, Altered blood lipid level
Written By
Reviewed By
MD (Pharmacology), MBBS
Last updated:
15 Sep 2020 | 04:24 AM (UTC)

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Available Medicine for Chlorthalidone

CTDIpca Laboratories Ltd
85 to ₹1122 variant(s)
LupiclorLupin Ltd
53 to ₹974 variant(s)
ThaloricZuventus Healthcare Ltd
49 to ₹632 variant(s)
ThiaklorEmcure Pharmaceuticals Ltd
46 to ₹542 variant(s)
AquirisAkumentis Healthcare Ltd
50 to ₹592 variant(s)
New CHSystopic Laboratories Pvt Ltd
13 to ₹202 variant(s)
ChlorfidFidelity Lifesciences Pvt Ltd
42 to ₹502 variant(s)
ThiovasLakshya Life Sciences
40 to ₹522 variant(s)
ChlohatAkesiss Pharma Pvt Ltd
331 variant(s)
ZioneTorrent Pharmaceuticals Ltd
421 variant(s)

Expert advice for Chlorthalidone

  • Take it in the morning with breakfast to avoid getting up at night to urinate.
  • It makes you feel dizzy. Avoid driving and attention requiring activity until you know how it affects you.
  • Avoid alcohol intake while taking Chlorthalidone as it may increase the dizziness. 
  • It may cause a sudden drop of sodium level in blood. Avoid low sodium diet while you are taking this medication.
  • Monitor your blood pressure after starting Chlorthalidone, and notify your doctor if it does not lower down.
  • Notify your doctor if you experience dizziness, tiredness, or muscle weakness that does not go away.
  • Inform your doctor if you are pregnant, planning pregnancy or breastfeeding. 

Frequently asked questions for Chlorthalidone


Q. Can I drink alcohol while taking Chlorthalidone?

No, do not take alcohol while on treatment with Chlorthalidone. Taking alcohol with Chlorthalidone may lower your blood pressure suddenly making you feel dizzy and lightheaded.

Q. What happens if I take more than the recommended dose of Chlorthalidone?

If you take more than the prescribed dose of Chlorthalidone, you may experience nausea, lightheadedness, weakness, fast or irregular heart beat, sleepiness, muscle cramps and pain, difficulty in breathing. Taking this medicine in high doses may even cause a heart attack. In a situation like this, contact your doctor immediately or seek emergency help in a nearby hospital.

Q. Can I take ibuprofen with Chlorthalidone?

This combination is best avoided since the two medicines may interfere with each other. However, if your doctor advises you to take both ibuprofen and Chlorthalidone, you will need to keep a regular check on your blood pressure and also monitor your kidney function tests.

Q. Does Chlorthalidone increase uric acid? Can it cause gout?

Yes, Chlorthalidone may raise uric acid levels. However, the occurrence of gout due to Chlorthalidone is very rare.

Q. Does Chlorthalidone cause skin cancer?

No, there have been no reports of Chlorthalidone causing skin cancer. However, in rare cases, this medicine can make the skin more sensitive to sunlight than usual. If you are exposed to direct sunlight you may get skin rash, so wear protective clothing and use sunscreen.


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