Infimab Injection is used for the treatment of various inflammatory conditions of the joints (rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis), skin (psoriasis), and bowel (ulcerative colitis, Crohn’s disease). It reduces inflammation in these conditions by blocking TNF alpha.

Infimab Injection is given as an infusion (slow drip) into a vein under the supervision of a doctor. You will be monitored while you are given this medicine. The dose and how often you need it will be decided by your doctor so that you get the right amount to control your symptoms. Make sure that you turn up for all your injections as per the schedule advised by your doctor. Taking this medicine regularly will greatly help to relieve your symptoms.

The most common side effects seen with this medicine include headache, sinus inflammation, upper respiratory tract infection, abdominal pain, and pharyngitis (pain or irritation in the throat). Some people may experience fever, chills, sweating, etc. due to an infusion reaction while this medicine is administered. Consult your doctor if any of the side effects persist or bother you. You may get infections more easily when you are being treated with this medicine. Tell your doctor right away if you develop any symptoms of an infection like fever, cough, rash, loose stools, or flu-like symptoms.

Before the start of treatment, let your doctor know if you have heart failure or tuberculosis or another serious infection like pneumonia or if you the hepatitis B virus. Pregnant and breastfeeding women should also consult their doctor before using this medicine. Some other medicines may react with this medicine so talk to your doctor about other medications you are taking as well. During treatment, your doctor will advise some tests to monitor your blood cell counts and track your progress.

Uses of Infimab Powder for Injection

Benefits of Infimab Powder for Injection

In Rheumatoid arthritis

Infimab Injection reduces pain, stiffness, and swelling in your joints and slows down the progression of bone and joint damage. This will help you do normal daily activities more easily and thus improve your quality of life. The medicine is given as an injection is given by a doctor or nurse and should not be self-administered.

In Ankylosing spondylitis

Ankylosing spondylitis is a rare type of arthritis that affects the spine or larger joints. It usually starts in your lower back and can spread up to your neck or damage joints in other parts of your body. Infimab Injection helps reduce pain, stiffness and swelling in your spine and joints. It helps improve flexibility and prevents disease progression. This will help you lead a better and active life.

In Psoriasis

Psoriasis is a condition where the skin cells in the body grow too quickly and form scales and dry patches. They can grow anywhere, but most appear on the scalp, elbows, knees, and lower back. Infimab Injection reduces the scaly, itchy patches which may develop on the different parts of the body. It may take several months to become fully effective. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.

In Ulcerative colitis

Ulcerative colitis is a disease of the large intestine (colon) and rectum in which the lining of the bowel becomes red and swollen. This can lead to bleeding, frequent diarrhea and abdominal pain. It relieves these symptoms and also helps you to stay well by preventing them from coming back. You should drink plenty of fluids while taking on treatment with this medicine to make sure you stay hydrated.

In Crohn’s disease

Crohn’s disease is a chronic (long-term) inflammatory disease of the intestines. The most common symptoms are diarrhea and pain in your abdomen. Infimab Injection helps reduce the inflammation, relieve the symptoms, and prevent them from coming back.

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Side effects of Infimab Powder for Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Infimab

Headache
Sinus inflammation
Upper respiratory tract infection
Infusion reaction
Abdominal pain
Sore throat

How to use Infimab Powder for Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Infimab Powder for Injection works

Infimab Injection is a monoclonal antibody that blocks a protein in immune system called TNF (tumor necrosis factor) that causes inflammation (pain and swelling) in joints.

Safety advice

Alcohol

SAFE

Consuming alcohol with Infimab Injection does not cause any harmful side effects.

Pregnancy

CONSULT YOUR DOCTOR

Infimab Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CAUTION

Infimab Injection should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.

Driving

CONSULT YOUR DOCTOR

It is not known whether Infimab Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.

Kidney

CONSULT YOUR DOCTOR

There is limited information available on the use of Infimab Injection in patients with kidney disease. Please consult your doctor.

Liver

CONSULT YOUR DOCTOR

There is limited information available on the use of Infimab Injection in patients with liver disease. Please consult your doctor.

What if you forget to take Infimab Powder for Injection?

If you miss a dose of Infimab Injection, please consult your doctor.\n

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Infimab Injection

₹31024/Powder for Injection

Remicade Injection

Janssen Pharmaceuticals

₹20519/powder for injection

36% cheaper

Quick tips

Infimab Injection is injected into a vein (intravenous infusion) under the supervision of a doctor. It is usually administered at 0, 2, 6 weeks and then once every 8 weeks.
It may take some time before you start to feel better after getting this medicine. However, it is important that you do not miss any dose and show up for your next infusion as per the schedule advised by your doctor.
Infimab Injection can make it difficult for your body to fight infections. Inform your doctor if you notice any fever, cough, runny nose, rash, loose stools or flu-like symptoms.
Inform your doctor if you have ever had tuberculosis or if you have been in close contact with someone who has or had tuberculosis. Your doctor may advise you certain tests to screen for tuberculosis before starting treatment with this medicine.
Inform your doctor if you have or ever had the hepatitis B virus infection. Your doctor may test you for hepatitis B virus before starting treatment with this medicine.
You may be advised regular blood tests to monitor blood counts while taking this medication.

Fact Box

Chemical Class

Monoclonal antibody (mAb)

Habit Forming

Therapeutic Class

PAIN ANALGESICS

Action Class

Disease Modifying Anti-Rheumatoid Drugs (DMARDs)- Biologics

Patient concerns

Suffering from ultratics colitis i have done colonoscopy test 04 months back From 05 months how many months I have to take medicines is it cure completely

Dr. Kunal Parasar

Surgical Gastroenterology

Ulcerative colitis is a lifelong disease with remission and exacerbations. Durations of remission cant b predicted all d time

Hi, I was diagnosed for Ulcerative Colitis in 2009. I was administered with Mesacol , I was back to normal. In past 1 month , after having food lunch or dinner I feel uneasy such as indigestion, having to force for motions next day. Sometimes Iam unable to pass motions. I feel tired also. Pls suggest.

Dr. Kunal Parasar

Surgical Gastroenterology

Ulcerative colitis is a lifong disease q with remission and exacerbation . U should b under constant follow up of ur gastroenterologist

Suffering from severe lower back pain since 6 years. As per MRI it is lumbar spondylosis,but Doctor told that it is one of the types of arthritis in which bridge is getting formed on spine Is there any permanent solution .at present taking Sazo 500 twice a day

Dr. Akshat Goel

Orthopaedics

It's called Ankylosing spondylitis". no permanent cure for this All you need to do is to exercise each and every joint of your body regularly "Along with the medication

User feedback

Patients taking Infimab Injection

Once A Month

37%

Once A Day

26%

Once A Week

16%

Twice A Month

11%

Four Times A *

Twice A Day

*Four Times A Day

What are you using Infimab Powder for Injection for?

Ankylosing sp*

60%

Rheumatoid ar*

25%

Crohn’s disea*

Ulcerative co*

Psoriasis

*Ankylosing spondylitis, Rheumatoid arthritis, Crohn’s disease, Ulcerative colitis

How much was the improvement?

Poor

34%

Average

34%

Excellent

31%

What were the side-effects while using Infimab Injection?

Headache

21%

Sinus inflamm*

21%

No Side Effec*

14%

Abdominal pai*

14%

Nausea

14%

*Sinus inflammation, No Side Effect, Abdominal pain

How do you take Infimab Powder for Injection?

With food

50%

With or witho*

43%

Empty stomach

*With or without food

Please rate Infimab Injection on price

Expensive

93%

Not Expensive

FAQs

Q. Is Infimab Injection an immunosuppressant?

Yes, Infimab Injection is a type of immunosuppressant drug. It suppresses inflammation (pain and swelling) caused by your immune system in conditions like rheumatoid arthritis, etc. It works by recognizing and binding to certain special proteins in the body known as tumor necrosis factor (TNF alpha) which is responsible for causing inflammation. Blocking the TNF alpha helps suppress inflammation, pain and swelling.

Q. Is Infimab Injection dangerous?

Infimab Injection acts on the immune system and may reduce your ability to fight infections. This may increase the risk of getting serious infections that may spread throughout the body. These infections may be life threatening and may need to be treated in a hospital. Therefore your doctor will monitor you for any infection before starting and during your treatment. Inform your doctor if you develop a fever or any other sign of infection while taking Infimab Injection. Furthermore, there are some reports which suggest that Infimab Injection may increase the risk of some types of cancer. However, remember that your doctor has prescribed this medicine to you because he has judged the benefits to you to be greater than any potential risks. Consult with your doctor if you have any further concerns.

Q. How do I take Infimab Injection?

You will have to visit the hospital to get this medicine whenever you have a dose scheduled. Infimab Injection is an intravenous infusion that is given via a drip into a vein in your arm over a two hour period under the supervision of a healthcare professional. After your first treatment, you will be given a second infusion after 2 weeks and third infusion 4 weeks later. After that, usually another infusion is given in every 8 weeks. Please consult your doctor to know the schedule that suits your condition best.

Q. Can Infimab Injection cause liver damage?

Yes, in rare cases the liver may be affected. Contact your doctor in case you experience fever, dark brown-colored urine, extreme tiredness (severe fatigue) and pain on the right side of your stomach area (right-sided abdominal pain). You must also inform your doctor if you develop jaundice (skin and eyes turn yellow).

Q. Does Infimab Injection affect the heart?

Yes, Infimab Injection may cause heart problems though not in everyone. It may cause heart attack (which can even lead to death), decreased blood flow to the heart or abnormal rhythm of the heart. This generally occurs within 24 hours of beginning of infusion. Symptoms may include chest discomfort or pain, arm pain, stomach pain, shortness of breath or anxiety. Other symptoms may include lightheadedness, dizziness, fainting, sweating, nausea (feeling sick), vomiting, fluttering or pounding in your chest, a fast or a slow heartbeat, and swelling of your feet. Tell your doctor immediately if you experience these symptoms.

Q. How soon can I experience relief in symptoms after taking Infimab Injection?

This varies from person to person depending on the condition. However, in most cases, while improvement in symptoms appears within 2 weeks of starting Infimab Injection, the maximum benefits may be noticed after 4 weeks.

Q. Can you drink alcohol while taking Infimab Injection?

Though alcohol does not interfere with the working of Infimab Injection, it is best to avoid alcohol. Discuss with your doctor if you are not sure.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Furst DE, Ulrich RW, Varkey-Altamirano C. Nonsteroidal Anti-Inflammatory Drugs, Disease Modifying Antirheumatic Drugs, Nonopioids Analgesics, & Drugs Used in Gout. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 633-34.
Wallace JL, Sharkey KA. Pharmacotherapy of Inflammatory Bowel Disease. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1359.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 712-13.
Infliximab. Hoddesdon, Hertfordshire: Merck Sharp & Dohme Limited; 1999 [18 Oct. 2018]. [Accessed 23 Jan. 2019] (online) Available from:
Drugs.com. Infliximab Pregnancy and Breastfeeding Warnings. [Accessed 02 Apr. 2019] (online) Available from:

Marketer details

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Address: Plot no 107/108,Namli block , Ranipool, East Sikkim 737135

Country of origin: India

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