Gestsafe 5mg Tablet

Reviewed By Dr. Rajeev Sharma, MBA, MBBS

Last updated on 04 Jan 2026 | 08:36 PM (IST)

Gestsafe 5mg Tablet is a synthetic progesterone derivative that is used in the treatment of recurrent miscarriages (pregnancy loss) and premature labor.

Genuine

Authenticity Assured

Prescription

required

178 people

viewed recently

Get by

Tuesday, 14 April

₹120

₹132

9% off

Get for

₹102

on orders above ₹1200

Use Code 1MGNEWPLUS

Get for

₹110

on orders above ₹300

Use Code 1MGNEW

1/2

10 tablets

Save more with additional offers

Pay with Amazon Pay Balance and get cashback up to Rs. 100 with minimum cashback of Rs. 20

Earn cashback up to Rs. 100 with Amazon Pay Later

Assured cashback up to ₹300 on minimum payment of ₹300 using Paytm UPI*

Save more with additional offers

Pay with Amazon Pay Balance and get cashback up to Rs. 100 with minimum cashback of Rs. 20

Earn cashback up to Rs. 100 with Amazon Pay Later

Assured cashback up to ₹300 on minimum payment of ₹300 using Paytm UPI*

10% cashback up to 200 on Min Transaction of Rs.1000, for first time users of Airtel Payments Bank.

Get cashback up to ₹500

Get upto Rs.500 Cashback on minimum transaction of Rs.999/- with Mobikwik Wallet.

Get upto Rs.150 Cashback

General Information

Contains

Allylestrenol (5mg)

Marketer

Axennic Pharmaceuticals Private Limited

Storage

Store below 30°C

The content is shown in English

Product introduction

Gestsafe 5mg Tablet can be taken with or without food, but take it at the same time to get the most benefit. It should be taken as your doctor's advice. The dose and how often you take it depends on what you are taking it for. Your doctor will decide how much you need to improve your symptoms. Swallow the tablets whole with a glass of water. You should take this medicine for as long as it is prescribed for you. Do not miss even a single dose, if in any case, you missed dose, take it as soon as you remember or better to skip the missed dose and continue with regular dosing.

The most common side effects of this medicine include edema (swelling), bloating, headache, depression, fatigue, altered libido, irregular menstrual cycle, gastrointestinal disturbances, and excessive hair growth. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them.

Before taking this medicine, let your doctor know if you have ever had undiagnosed vaginal bleeding, or incomplete abortion, or have heart disease or kidney problems. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works.

Uses of Gestsafe Tablet

Benefits of Gestsafe Tablet

Treatment of Recurrent miscarriage
Gestsafe 5mg Tablet helps to prevent miscarriage in such women who have had such complications in an earlier pregnancy. It improves the thickness of the lining of the uterus (womb) and also attachment of the baby to the uterus. This makes sure that there are no abnormal contractions of the uterus which may lead to premature delivery.

Treatment of Premature Labor
Gestsafe 5mg Tablet prevents abnormal contractions of uterus muscles and relaxes them. It widens blood vessels to help increase blood flow and improve circulation to the smooth muscles of the uterus. This prevents premature labor and miscarriage. Take it as prescribed and follow your doctor’s instructions carefully to get maximum benefit.

Side effects of Gestsafe Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Gestsafe

Headache
Fatigue
Altered libido
Irregular menstrual cycle
Gastrointestinal disturbance
Excessive hair growth on face
Edema (swelling)
Bloating
Depression

How to use Gestsafe Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Gestsafe 5mg Tablet may be taken with or without food.

How Gestsafe Tablet works

Gestsafe 5mg Tablet is a progestin (female hormone). It helps in maintaining pregnancy by promoting the attachment of the embryo to lining of the womb and improving blood flow to the placenta. It also relaxes the uterus muscles thereby preventing premature labour.

All substitutes for Gestsafe 5mg Tablet

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Gestsafe 5mg Tablet is used to treat repeated miscarriages and to prevent premature birth in pregnant women.
Take it as per dose and duration suggested by your doctor.
It must be discontinued after delivery as it may affect the baby.
Do not drive or do anything that requires concentration until you know how the medication affects you.
Do not stop taking it suddenly without talking to your doctor first.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Gestsafe 5mg Tablet. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Information regarding the use of Gestsafe 5mg Tablet during pregnancy is not available. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of Gestsafe 5mg Tablet during breastfeeding is not available. Please consult your doctor.

Driving

UNSAFE

Gestsafe 5mg Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CONSULT YOUR DOCTOR

There is limited data available on the use of Gestsafe 5mg Tablet in patients with kidney disease. Please consult your doctor.

Liver

CONSULT YOUR DOCTOR

There is limited data available on the use of Gestsafe 5mg Tablet in patients with liver disease.

Interaction with drugs

Taking Gestsafe with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Severe

Tamoxifen (Oral Route)

Do not consume Tamoxifen with Allylestrenol if you have or had breast cancer. If essential, consult your doctor. Allylestrenol may reduce the efficacy of Tamoxifen.

Severe

Letrozole (Oral Route)

Do not consume Letrozole with Allylestrenol if you have or had breast cancer. If essential, consult your doctor.

Severe

Anastrozole (Oral Route)

Do not consume Anastrozole with Allylestrenol if you have or had breast cancer. If essential, consult your doctor. Allylestrenol may reduce the efficacy of Anastrozole.

Severe

Raloxifene (Oral Route)

Do not consume Raloxifene with Allylestrenol. If concurrent use is essential, please consult your doctor. Allylestrenol may reduce the efficacy of Raloxifene.

Severe

Rifampicin (Injection Route)

Use other methods of contraception (IUDs, depot or barrier methods) both during and for 28 days following the discontinuation of Rifampicin. Rifampicin may reduce the efficacy of Allylestrenol.

Frequently asked questions

Can Gestsafe 5mg Tablet be used as a birth control medicine?

No, Gestsafe 5mg Tablet cannot be used as a birth control medicine. It is a hormone preparation used to treat repeated miscarriages and to prevent premature birth in pregnant women. You may need to use contraceptive methods to avoid pregnancy. Consult with your doctor to seek options for contraceptives.

In what conditions Gestsafe 5mg Tablet should be avoided?

This medicine should not be used in patients with a history of blood clot events, severe liver disease, incomplete abortion, hormone-dependent carcinoma, and hypersensitivity.

I have started feeling depressed after taking Gestsafe 5mg Tablet? Is this normal?

Depression is one of the common side-effects of this medicine. It is advisable to inform your doctor immediately if you get thoughts about harming yourself. He/she might suggest a suitable alternative based on your condition.

What are the functions of natural progesterone?

Progesterone helps prepare your body for conception and pregnancy and regulates the monthly menstrual cycle. One of progesterone's most important functions is its role in thickening the lining of the uterus each month. The enriched endometrial lining is prepared to receive and nourish a fertilized egg in pregnant women.

Fact Box

Chemical Class

Estrane steroids

Habit Forming

Therapeutic Class

GYNAECOLOGICAL

Action Class

Progestins- Others

Related lab tests

Anti Phospholipid Antibody IgG

Anti Phospholipid Antibody IgM

Chromosome Analysis, Blood

Thyroid Stimulating Hormone

References

Allylestrenol [Package Insert]. Dhaka, Bangladesh: The Acme Laboratories Ltd.

Want to know more

We provide you with authentic, trustworthy and relevant information

Have issue with the content

Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Axennic Pharmaceuticals Private Limited
Address: 402/A, GOKHALENAGAR SENAPATI BAPAT ROAD PUNE MH 411016 IN

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Gestsafe 5mg Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

Lab tests offered by us

Why we need a prescription?

Provide right medicines

Prescriptions are complex documents. We proof read and recheck at various steps to provide you the right medication in the correct form and dose

In accordance with the law

Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945

Gestsafe 5mg Tablet

Save more with additional offers

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Gestsafe Tablet

Benefits of Gestsafe Tablet

Side effects of Gestsafe Tablet

How to use Gestsafe Tablet

How Gestsafe Tablet works

All substitutes for Gestsafe 5mg Tablet

Gestin Tablet

Maintane Tablet

ANin Tablet

Maintane Tablet

Alltenol 5mg Tablet

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Tamoxifen (Oral Route)

Letrozole (Oral Route)

Anastrozole (Oral Route)

Raloxifene (Oral Route)

Rifampicin (Injection Route)

Frequently asked questions

Can Gestsafe 5mg Tablet be used as a birth control medicine?

In what conditions Gestsafe 5mg Tablet should be avoided?

I have started feeling depressed after taking Gestsafe 5mg Tablet? Is this normal?

What are the functions of natural progesterone?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Anti Phospholipid Antibody IgG

Anti Phospholipid Antibody IgM

Chromosome Analysis, Blood

Thyroid Stimulating Hormone

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

In case of any issues, contact us

Lab tests offered by us

Related/Popular tests