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    Information about Rifabutin

    Rifabutin uses

    Rifabutin is used in the treatment of tuberculosis and tuberculosis with HIV infection.

    How rifabutin works

    Rifabutin is an antibiotic. It works by inactivating a bacterial enzyme (RNA-polymerase) which is required by TB bacteria to make essential proteins and to reproduce.

    Common side effects of rifabutin

    Decreased white blood cell count, Anemia (low number of red blood cells), Nausea, Rash, Muscle pain

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    Expert advice for Rifabutin

    • Taking rifabutin may change the color of your urine to red/orange. You may also experience coloring of the skin and other body fluids and also of soft contact lenses.
    • You may be regularly monitored with blood tests and chest x-rays to check that you do not have active tuberculosis or any other mycobacterial disease.
    • You may also undergo regular eye examination while using rifabutin.
    • Seek immediate medical attention if you develop sudden wheeziness, difficulty in breathing, pain in the chest, swelling of eyelids, face or lips, rash or itching.
    • Use non hormonal birth control techniques (condom, diaphragm with spermicide) to prevent pregnancy, as rifabutin can make birth control pills less effective.

    Content on this page was last updated on 19 April, 2018, by Dr. Varun Gupta (MD Pharmacology)