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20 Jun 2019 | 04:25 PM (IST)
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Donecept 10 Tablet

Prescription Required
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Overview

Uses of Donecept Tablet

Donecept Tablet side effects

Common
  • Nausea
  • Vomiting
  • Loss of appetite
  • Fatigue
  • Insomnia (difficulty in sleeping)
  • Diarrhea
  • Muscle cramp

How to use Donecept Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Donecept 10 Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Donecept Tablet works

Memory loss in Alzheimer’s disease occurs due to disturbances of signal transmission in the brain. Donecept 10 Tablet is a cholinesterase inhibitor. It works by increasing the levels of a chemical messenger (acetylcholine) involved in transmmission of nerve signals. This improves memory and thinking.

Donecept Tablet related warnings

Alcohol
CAUTION
It is unsafe to consume alcohol with Donecept 10 Tablet.
Pregnancy
WEIGH RISKS VS BENEFITS
Donecept 10 Tablet may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the fetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Lactation
CAUTION
Donecept 10 Tablet is probably unsafe to use during lactation. Limited human data suggest that the drug could represent a significant risk to the baby.
Driving
Do not drive unless you are feeling well.
Alzheimer’s disease may impair your ability to drive unless your doctor tells you that it is safe to do so. Also, your medicine can cause tiredness, dizziness and muscle cramp.
Kidney
Donecept 10 Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Donecept 10 Tablet may not be needed in these patients. Please consult your doctor.
Liver
CAUTION
Donecept 10 Tablet should be used with caution in patients with liver disease. Dose adjustment of Donecept 10 Tablet may be needed. Please consult your doctor.

What if you miss a dose of Donecept Tablet?

If you miss a dose of Donecept 10 Tablet, skip it and continue with your normal schedule. Do not double the dose.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Donecept 10 Tablet
₹15.07/Tablet
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Donep 10 Tablet
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Alzil 10 Tablet
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Cognidep 10mg Tablet
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Senpezil 10 Tablet
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Expert Advice

  • You have been prescribed Donecept 10 Tablet to slow down the progression of Alzheimer's disease.
  • It does not cure Alzheimer's but may help with brain function and doing daily activities.
  • Take it with food to avoid an upset stomach.
  • It may cause diarrhea, nausea, and vomiting. Drink plenty of fluids to keep yourself hydrated while taking Donecept 10 Tablet.
  • Monitor your body weight regularly as both Donecept 10 Tablet and  Alzheimer's disease can cause weight loss.
  • Do not drive or do anything that requires mental focus until you know how Donecept 10 Tablet affects you.
  • Inform your doctor if you develop muscle tremors, especially if you have Parkinson’s disease.

Interaction with Drugs

Taking Donecept with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Zosert
MODERATE
Brand(s): Leparox, Prx
MODERATE
Brand(s): Flotin, Serodep
MODERATE
Brand(s): Kopram
MODERATE
Brand(s): Fungis, EF Z, Rocflu
MINOR
Brand(s): Indizole, Itraspan, Itzo
MINOR

Patient Concerns

Questions Related to Donecept

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Parkinson's disease tremors ,Insomnia.
Dr. Ravi Shankar M.
Ayurveda
Use Dhanadanayanadi kashayam 15ml twice a day with 15 ml water before food and Zandopa 10 grams twice a day witk milk after food and Tab Dhanvantari Vati 1-0-1 after food for 2 months
Hi my mom had Parkinson's disease but didn't get any operation but using tablets syndopa last night she take another tablet of pain killer with it by the morning my mom to full shivering of hands and legs so what do u suggest to do?
Dr. Vikas Sharma
Neurologist
need to examine to opine
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Do you have any questions related to Donecept 10 Tablet?

User Feedback


FAQs

Q. Why is Donecept taken at night?

Donecept is recommended to be taken before going to bed to reduce gastrointestinal side effects or nausea, which is commonly seen in some patients in the first few weeks of treatment.

Q. Do the gastrointestinal side effects due to Donecept persist for a long time?

Gastrointestinal side effects may appear during the first few weeks of treatment with Donecept. This can be minimized by taking Donecept at bedtime and with food. Generally, these side effects are mild and disappear within a few weeks with continued treatment.

Q. How long does it take for Donecept to start working?

Within the first month of treatment with Donecept, you may experience improvement in thinking and remembering (cognitive effect). However, it may take about 12 weeks to see the full benefits.

Q. When should Donecept be stopped?

Do not stop Donecept without consulting your doctor. This medicine only helps to control your condition but does not cure it. Therefore, it may take several weeks to show benefits, so do not be discouraged if you do not see an improvement straight away. But, in case your condition starts worsening and you feel that it is no longer helping you, then you should consult a doctor before stopping it.

Q. For how long does Donecept stay in your system?

Donecept gets removed from the body very slowly. It takes about two weeks or more for Donecept to be completely removed from the system.

Q. Does Donecept cause depression?

No, Donecept does not cause depression. If you are experiencing symptoms, then it could be due to existing Alzheimer’s disease.

Q. What if I take more than the prescribed dose of Donecept?

Taking more than the recommended dose of Donecept may cause vomiting, increased sweating or saliva production, slow heartbeat, dizziness, difficulty in breathing, seizures or fits, weakness, and inability to control your bowel motions or passing of urine (incontinence). You should seek immediate help from a doctor or emergency service of a nearby hospital.

Q. I have been taking indomethacin for arthritis. Can I take Donecept?

Donecept does not interfere with the working of indomethacin, but indomethacin individually increases the risk of stomach bleeding when taken for a long time. Therefore, if you experience any symptoms of stomach bleeding, consult your doctor immediately.

Q. Does Donecept cause hallucinations?

Hallucinations are a common side effect of Donecept, though not everyone is affected. Other common psychiatric side effects include agitation, aggressive behavior, nightmares, and abnormal dreams.

Q. Who should not take Donecept?

Donecept should not be taken by patients who have hypersensitivity to Donecept hydrochloride, piperidine derivatives, or to any active ingredients used in the medicine. Also, it should not be used during pregnancy unless clearly necessary.

Q. Can it cause insomnia?

Yes, insomnia (sleeplessness) is a common side effect of Donecept. Dizziness and fainting can also be seen as common side effects. Though these side effects are common, they do not occur in everyone.

Related Products

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Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
  1. Stahl SM, editor. Donepezil. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 199-202.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 426-27.
  3. Donepezil hydrochloride. Woodcliff Lake, New Jersey: Eisai Inc.; 1996 [revised Feb. 2012]. [Accessed 25 Jan. 2019] (online) Available from:External Link
  4. Donepezil. Hatfield, Hertfordshire: Eisai Ltd.; 1997 [revised 11 May 2018]. [Accessed 25 Jan. 2019] (online) Available from:External Link
  5. Donepezil hydrochloride. South Ruislip, UK: Aurobindo Pharma - Milpharm Ltd.; 2013 [revised 23 Nov. 2017] [Accessed 19 Jun. 2019] (online) Available from:External Link
  6. Central Drugs Standard Control Organisation (CDSCO). [Accessed 22 Mar. 2019] (online) Available from:External Link
Manufacturer/Marketer Address
Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013
A licensed pharmacy from your nearest location will deliver Donecept 10 Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your prescription and the availability of this medicine.
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