Depogen 150mg Injection

Prescription Required
Store at room temperature (10-30°C)


Depogen 150mg Injection is used for contraception (preventing pregnancy). It helps to prevent development and release of egg from the ovaries during menstrual cycle thus prevents pregnancy.

Depogen 150mg Injection is administered only by or under the supervision of doctor. It should be taken as your doctor advice. Your doctor will decide how much you need to take and for how much time. You should take this injection for as long as it is prescribed for you.

The most common side effects of this medicine include headache, dizziness, abdominal pain, nervousness, weight gain, and breast tenderness. If any of these bothers you, let your doctor know. There may be ways of reducing or preventing them. It may also cause irregular menstrual cycle, spotting or your menstrual bleeds to stop altogether. Inform your doctor if you get heavy or prolonged bleeding.

Before taking this medicine, you must let your doctor know if you ever had any problems like history of blood clots, stroke, heart attack, liver, or bleeding problems. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. You must not take it if you are pregnant.

Uses of Depogen Injection

Benefits of Depogen Injection

In Contraception

Depogen 150mg Injection contains an injectable synthetic hormone that behaves like the natural hormone progesterone. This hormone stops you from getting pregnant in multiple ways. Firstly, it prevents an egg from being released from your ovaries. Secondly, it makes the fluid (mucus) in your cervix thicker, which makes it more difficult for sperm to enter the womb. Additionally, it prevents the thickening of the lining of your womb, thereby making it unfavorable for an egg to grow in it. Depogen 150mg Injection is a reliable and safe method for short-term contraception if used correctly. It does not interrupt with sex and is an effective contraception method for around 3 months (13 weeks) after which you need to visit the doctor for another injection.

Side effects of Depogen Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Depogen

  • Headache
  • Dizziness
  • Abdominal pain
  • Nervousness
  • Weight gain
  • Breast tenderness
  • Irregular menstrual cycle
  • Weakness

How to use Depogen Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Depogen Injection works

Depogen 150mg Injection is a progestin (female hormone). It works by preventing an egg from developing fully and being released from the ovaries during your menstrual cycle. It also alters the lining of your womb and thickens the mucus at the entrance of the womb, making it more difficult for the sperm to enter. This prevents pregnancy.

Safety Advice

Caution is advised when consuming alcohol with Depogen 150mg Injection. Please consult your doctor.
Depogen 150mg Injection is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Depogen 150mg Injection is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Nonhormonal contraceptives are preferred in breastfeeding women, especially during the first 4 weeks postpartum
Depogen 150mg Injection may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
There is limited information available on the use of Depogen 150mg Injection in patients with kidney disease. Please consult your doctor.
Depogen 150mg Injection is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
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Quick Tips

  • Depogen 150mg Injection is used for preventing pregnancy (contraception).
  • To avoid the risk of becoming pregnant you must take the injection once after every 12 weeks.
  • It is usually given into the muscle of the buttock or upper arm.
  • The injection cannot be reversed once it has been given and its effects last for at least 12 weeks.
  • Fertility does return once the injections are stopped, but the time varies for each woman.
  • It may cause irregular bleeding, spotting or your menstrual bleeds to stop altogether. Inform your doctor if you get heavy or prolonged bleeding.
  • Long term use can cause a loss of bone mineral density and increase the risk of weak bones and osteoporosis.
  • Do not take Depogen 150mg Injection if you're pregnant or breastfeeding, or have a history of blood clots, stroke, heart attack, liver problems, or bleeding problems.

Fact Box

Chemical Class
Gluco/Mineralocorticoids, Progestogins Derivatives
Habit Forming
Therapeutic Class
Action Class
Progestins (First generation)

Patient Concerns

Contraception and birth control
Dr. Megha Tuli
Obstetrics and Gynaecology
How can I help you. Please be specific
I want to ask about better contraception
Dr. Pranay Gandhi
copper t, ocp, condom all r good. its upto u to choose
Do you have any questions related to Depogen 150mg Injection ?

User Feedback


Q. What is Depogen 150mg Injection used for?

Depogen 150mg Injection is a birth control method for women. It is made up of a hormone similar to progesterone, which is naturally produced in the body. It helps to prevent the development and release of egg from the ovaries during menstrual cycle thus prevents pregnancy.

Q. When and how to take Depogen 150mg Injection ?

The first dose is usually given within 5 days of starting of your period. It is given as an injection into the muscle of the arm or buttocks, either by a doctor or nurse. A single dose of this injection is effective for 12 weeks. Therefore, after every 12 weeks you need to take this injection to avoid pregnancy.

Q. Does Depogen 150mg Injection provide 100% protection from pregnancy?

No, Depogen 150mg Injection is only 97% effective, which means 3 out of 100 women using Depogen 150mg Injection may get pregnant. However, if you are taking every dose on time then the medicine can be more than 99% effective.

Q. Can I become pregnant after I stop using Depogen 150mg Injection?

Yes, your fertility returns to normal after a few months of stopping Depogen 150mg Injection (on average three months, but it may take up to 1 year). However, if you are planning to get pregnant soon, avoid taking Depogen 150mg Injection unless otherwise prescribed by your doctor.

Q. What are the side effects of using Depogen 150mg Injection?

The side effects associated with Depogen 150mg Injection include irregular menstrual periods or no periods at all, weight gain, headache, stomach pain, dizziness, acne and breast tenderness. Do not worry, as most of these side effects are temporary. However, if these side effects persist, consult your doctor.

Q. When does Depogen 150mg Injection start working?

Depogen 150mg Injection starts working immediately if given within the first 5 days of beginning of your periods. But, if you receive the dose at another time of your menstrual cycle then it may take about 7 to 10 days to show effectiveness. Therefore, during these days, you must use some other contraceptive method such as condoms to avoid pregnancy.

Q. What are the advantages of using Depogen 150mg Injection?

Depogen 150mg Injection is almost 100% effective and has many advantages. A single dose works for at least 12 weeks. During that time, you do not need to take daily oral contraceptive pills. It does not interfere with sexual intercourse. Moreover, it also reduces the risk of endometrial cancer (cancer of the lining of the uterus) by 80%. It may also be helpful in relieving painful periods.

Q. What if I am late for my injection?

Depogen 150mg Injection injections should be given every 12 weeks. If you wait longer than 13 weeks between injections, you may need to take a pregnancy test before your next injection. You should opt for other methods of contraception, like condoms, for 14 days after having the late injection.

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1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.


  1. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 850-54.
  2. Medroxyprogesterone acetate. Pfizer: Puurs, Belgium: 2018. [Accessed 21 Jan. 2019] (online) Available from:External Link
  3. Medroxprogestrone. [Accessed 03 Apr. 2019] (online) Available from:External Link
  4. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 03 Apr. 2019] (online) Available from:External Link

Manufacturer/Marketer Address

Mahilamandiram Road, Poojappura Thiruvananthapuram - 695 012, Kerala, India
Country of Origin: India

Inclusive of all taxes
1 ml in 1 vial


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