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Defmind 50mg Tablet

Written By Dr. Syeda Aafia, MBA, BDS
Reviewed By Dr. Mekhala Chandra, MD, MBBS
Last updated on 25 Nov 2025 | 03:05 PM (IST)
Defmind 50mg Tablet is a prescription medicine used in the treatment of depression. This medicine helps by increasing the level of chemical messengers (serotonin and noradrenaline) in the brain that have a calming effect on the brain and relaxes the nerves, thus treating your depression.
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General Information

Contains

Desvenlafaxine (50mg)

Marketer

Brainwave Healthcare Pvt Ltd

Storage

Store below 30°C
The content is shown in English
Defmind 50mg Tablet image
Defmind 50mg Tablet image
Defmind 50mg Tablet image
Defmind 50mg Tablet image
Defmind 50mg Tablet image
Defmind 50mg Tablet image
Defmind 50mg Tablet image

Product introduction

Defmind 50mg Tablet is taken by mouth with or without food. Take it at a fixed time each day to maintain consistent level of medicine in the blood. In case you have missed a dose, take it as soon as you remember. Do not skip any doses and finish the full course of treatment even if you feel better. It is important that this medication is not stopped suddenly without talking to doctor as this may worsen your symptoms.

Some common side effects of this medicine includes nausea, vomiting, insomnia (difficulty in sleeping), and constipation. It may cause an increase in blood pressure, especially during the first month of treatment, monitor your blood pressure regularly. It may even cause dizziness and sleepiness, do not drive or do anything that requires mental focus until you know how this medicine affects you. It is important to inform your doctor if you develop any unusual changes in mood as it may lead to suicidal thoughts.

Uses of Defmind Tablet

Benefits of Defmind Tablet

Depression
Depression is a mood disorder that affects emotional well-being, energy, and daily functioning. Defmind 50mg Tablet is used to manage depression by helping to restore balance in brain chemicals that influence mood. It supports better emotional stability, reduces symptoms like sadness, and helps improve overall quality of life.

Side effects of Defmind Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Defmind
  • Anxiety
  • Constipation
  • Decreased appetite
  • Dizziness
  • Increased sweating
  • Insomnia (difficulty in sleeping)
  • Nausea
  • Sexual dysfunction
  • Vomiting

How to use Defmind Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Defmind 50mg Tablet may be taken with or without food.

How Defmind Tablet works

Defmind 50mg Tablet works by increasing the levels of chemical messengers (serotonin and noradrenaline), natural substances in the brain that help maintain mental balance.

All substitutes for Defmind 50mg Tablet

For information purposes only. Consult a doctor before taking any medicine.

D-Venlor 50 Tablet

by Cipla Ltd
₹14.1/tablet
12% cheaper
<h3 class=bodySemiBold>D-Venlor 50 Tablet</h3>

Deswave 50mg Tablet

by Gentech Healthcare Pvt Ltd
₹8.6/tablet
47% cheaper
<h3 class=bodySemiBold>Deswave 50mg Tablet</h3>

Quick tips

  • Defmind 50mg Tablet helps in treating depression and anxiety.
  • It may take 2 to 4 weeks for Defmind 50mg Tablet to start working. Keep taking it as prescribed.
  • It may cause dizziness and sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
  • Avoid consuming alcohol when taking Defmind 50mg Tablet as it may cause excessive drowsiness and increase the risk of liver damage.
  • It may cause a sensation of restlessness, especially when you first start taking it. Inform your doctor if this happens to you.
  • Talk to your doctor if you notice sudden mood changes or develop suicidal thoughts.
  • Do not stop taking the medication suddenly without talking to your doctor.

Safety advice

Alcohol

Alcohol

CAUTION
Alcohol should be used with caution while taking Defmind 50mg Tablet.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Defmind 50mg Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Defmind 50mg Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Driving

Driving

UNSAFE
Defmind 50mg Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

CAUTION
Defmind 50mg Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Liver

Liver

CAUTION
Defmind 50mg Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Defmind with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Life-threatening

Moclobemide (Oral Route)

Do not consume Moclobemide with Desvenlafaxine. If Moclobemide is essential, ensure a gap of at least 1 week after discontinuing Desvenlafaxine. Please consult your doctor.
Life-threatening

Tranylcypromine (Oral Route)

Your doctor may monitor your potassium levels regularly.
Life-threatening

Selegiline (Oral Route)

Do not consume Selegiline with Desvenlafaxine. If Selegiline is essential, ensure a gap of at least 2 weeks after discontinuing Desvenlafaxine. Please consult your doctor.
Severe

Ziprasidone (Oral Route)

Watch out for symptoms such as tremors, fever, diarrhea or agitation and consult your doctor if you experience them. Your doctor may discontinue the medicines accordingly.
Severe

Amitriptyline (Oral Route)

Talk to your doctor if you notice any unusual symptoms. Your doctor may adjust the dose if required.

Frequently asked questions

The symptoms of depression like change in appetite and sleep patterns may show improvement within 1-2 weeks of starting Defmind 50mg Tablet. However, it may take about 5-6 weeks to see the full benefits of Defmind 50mg Tablet.
It has been shown to be effective in relieving symptoms of anxiety, though it is not approved for anxiety. It is used in anxiety disorders only when advised by the doctor.
Defmind 50mg Tablet can be taken either in the morning or in the evening. For best results, take this medicine at the same time each day. This will also help you remember to take it.
Defmind 50mg Tablet should be swallowed whole with water. It should not be cut, chewed, crushed or dissolved. Take it exactly as directed by your doctor.
Defmind 50mg Tablet belongs to a class of medicines known as serotonin and norepinephrine reuptake inhibitors (SNRIs). Serotonin and norepinephrine are chemical messengers in the brain which help maintain mental balance. Defmind 50mg Tablet works by increasing the levels of these two hormones in the brain.
Weight gain may occur with Defmind 50mg Tablet, though not in everyone. In case you notice weight gain after taking Defmind 50mg Tablet, consult your doctor or a nutritionist. Take a low calorie food, including more vegetables and fruits in your diet and exercise regularly.
Taking Defmind 50mg Tablet may cause a decrease in sexual desire and ability. It may also cause a delay in orgasm and ejaculation and sometimes ejaculation failure. Discuss with your doctor if you experience any of these symptoms while taking Defmind 50mg Tablet.

Fact Box

Chemical Class

Cyclohexanols

Habit Forming

No

Therapeutic Class

NEURO CNS

Action Class

Serotonin Norepinephrine Reuptake Inhibitors (SNRIs)

References

  1. Stahl SM, editor. Desvenlafaxine. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 175-80.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 375-77.
  3. Central Drugs Standard Control Organisation (CDSCO). [Accessed 22 Mar. 2019] (online) Available from:
  4. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Desvenlafaxine. [Updated 2018 Oct 31]. [Accessed 20 Feb. 2020] (online) Available from:
  5. Desvenlafaxine [Prescribing Information]. Philadelphia, PA: Wyeth Pharmaceuticals LLC; 2021. [Accessed 19 Jun. 2023]. (online) Available from:
  6. Desvenlafaxine Extended Release [Product Information Sheet]. Ahmedabad, Gujarat: Torrent Pharmaceuticals Ltd. 2014. [Accessed 20 Feb. 2024] (online) Available from: torrentian.com/pisheet/Upload/PI_Sheet/1536.pdf
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User feedback

Once A Day
80%
Twice A Day
20%
Depression
60%
Others
40%
Poor
42%
Average
33%
Excellent
25%
No Side Effect
29%
Dizziness
14%
Decreased appetite
14%
Anxiety
14%
Constipation
14%
With food
100%
Expensive
67%
Not Expensive
25%
Average
8%
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Brainwave Healthcare Pvt Ltd
Address: A- 37, Mangolpuri , Industrial Area, Phase - II Delhi - 110034

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Defmind 50mg Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's â„ž and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

Lab tests offered by us

Why we need a prescription?
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Prescriptions are complex documents. We proof read and recheck at various steps to provide you the right medication in the correct form and dose
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Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945
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