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Desvenlafaxine is used in the treatment of depression and diabetic nerve disease

How it works

Desvenlafaxine increases the levels of chemical messengers in the brain that helps in regulating the mood and treat depression.

Common side effects

Headache, Dizziness, Blurred vision, Decreased libido, Insomnia (difficulty in sleeping), Sleepiness, Vomiting, Weakness, Nausea, Dry mouth, Abdominal pain, Agitation, Lethargy, Dyspepsia, Increased sweating, Paresthesia (tingling or pricking sensation), Fatigue, Anxiety, Chills, Diarrhoea, Vertigo, Increased blood pressure, Decreased appetite, Flushing (sense of warmth in the face, ears, neck and trunk), Sleep disorder, Constipation, Tremor

Available Medicine

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Expert advice

  • Take Desvenlafaxine only as directed by your doctor. Do not take it more often or for a longer period of time. 
  • You may have to take Desvenlafaxine at least for 4 weeks or longer before you begin to feel better. 
  • Do not discontinue the use of Desvenlafaxine, unless the doctor has advised you. This may increase the chances of side effects.
  • Desvenlafaxine should be taken with food to minimize the chances of an upset stomach. 
  • Avoid driving after taking as it may cause drowsiness, blurred vision, dizziness and confusion. 
  • Avoid consuming alcohol when taking Desvenlafaxine, it may cause excessive drowsiness and calmness. 
  • Desvenlafaxine may cause a higher risk of suicidal thoughts and behaviour changes. 
  • Desvenlafaxine causes sleepiness, so it's good for people who have trouble sleeping (insomnia).

Frequently asked questions



Is desvenlafaxin same as venlafaxine?
Desvenlafaxine and venlafaxine belongs to same category of drugs with similar action, but their effect may vary upon individual response


Is desvenlafaxine an addictive?
No, patients should follow the advice of the doctor regarding its use


Is desvenlafaxine a SSRI/stimulant?
No, desvenlafaxine belongs to class of medication called as selective serotonin and norepinephrine reuptake inhibitors (SNRIs)

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Is desvenlafaxine safe?
Desvenlafaxine is safe, if used at prescribed doses for the prescribed duration as advised by your doctor


Does desvenlafaxine cause weight gain?
No, desvenlafaxine is not known to cause weight. Consult your doctor if you experience such side effects.

Content on this page was last updated on 27 March, 2017, by Dr. Varun Gupta (MD Pharmacology)