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D-Venlor 50 Tablet

Desvenlafaxine (50mg)

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D-Venlor 50 Tablet is a prescription medicine used in the treatment of depression. This medicine helps by increasing the level of chemical messengers (serotonin and noradrenaline) in the brain that have a calming effect on the brain and relaxes the nerves, thus treating your depression.

Written By Dr. Syeda Aafia, MBA, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 13 Apr 2026 | 10:23 AM (IST)

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General Information

Contains

Desvenlafaxine (50mg)

Marketer

Cipla Ltd

Storage

Store below 25°C

The content is shown in English

Product introduction

D-Venlor 50 Tablet is taken by mouth with or without food. Take it at a fixed time each day to maintain consistent level of medicine in the blood. In case you have missed a dose, take it as soon as you remember. Do not skip any doses and finish the full course of treatment even if you feel better. It is important that this medication is not stopped suddenly without talking to doctor as this may worsen your symptoms.

Some common side effects of this medicine includes nausea, vomiting, insomnia (difficulty in sleeping), and constipation. It may cause an increase in blood pressure, especially during the first month of treatment, monitor your blood pressure regularly. It may even cause dizziness and sleepiness, do not drive or do anything that requires mental focus until you know how this medicine affects you. It is important to inform your doctor if you develop any unusual changes in mood as it may lead to suicidal thoughts.

Uses of D-Venlor Tablet

Depression

Benefits of D-Venlor Tablet

Depression
Depression is a mood disorder that affects emotional well-being, energy, and daily functioning. D-Venlor 50 Tablet is used to manage depression by helping to restore balance in brain chemicals that influence mood. It supports better emotional stability, reduces symptoms like sadness, and helps improve overall quality of life.

Side effects of D-Venlor Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of D-Venlor

Anxiety
Constipation
Decreased appetite
Dizziness
Increased sweating
Insomnia (difficulty in sleeping)
Nausea
Sexual dysfunction
Vomiting

How to use D-Venlor Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. D-Venlor 50 Tablet may be taken with or without food.

How D-Venlor Tablet works

D-Venlor 50 Tablet works by increasing the levels of chemical messengers (serotonin and noradrenaline), natural substances in the brain that help maintain mental balance.

All substitutes for D-Venlor 50 Tablet

For information purposes only. Consult a doctor before taking any medicine.

Defmind 50mg Tablet

by Brainwave Healthcare Pvt Ltd

₹16.2/tablet

15% costlier

Deswave 50mg Tablet

by Gentech Healthcare Pvt Ltd

₹8.6/tablet

39% cheaper

Quick tips

D-Venlor 50 Tablet helps in treating depression and anxiety.
It may take 2 to 4 weeks for D-Venlor 50 Tablet to start working. Keep taking it as prescribed.
It may cause dizziness and sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
Avoid consuming alcohol when taking D-Venlor 50 Tablet as it may cause excessive drowsiness and increase the risk of liver damage.
It may cause a sensation of restlessness, especially when you first start taking it. Inform your doctor if this happens to you.
Talk to your doctor if you notice sudden mood changes or develop suicidal thoughts.
Do not stop taking the medication suddenly without talking to your doctor.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with D-Venlor 50 Tablet. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

D-Venlor 50 Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

CAUTION

D-Venlor 50 Tablet should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.

Driving

CONSULT YOUR DOCTOR

It is not known whether D-Venlor 50 Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.

Kidney

CAUTION

D-Venlor 50 Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.

Liver

CAUTION

D-Venlor 50 Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking D-Venlor with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Life-threatening

Moclobemide (Oral Route)

Do not consume Moclobemide with Desvenlafaxine. If Moclobemide is essential, ensure a gap of at least 1 week after discontinuing Desvenlafaxine. Please consult your doctor.

Life-threatening

Tranylcypromine (Oral Route)

Your doctor may monitor your potassium levels regularly.

Life-threatening

Selegiline (Oral Route)

Do not consume Selegiline with Desvenlafaxine. If Selegiline is essential, ensure a gap of at least 2 weeks after discontinuing Desvenlafaxine. Please consult your doctor.

Severe

Ziprasidone (Oral Route)

Watch out for symptoms such as tremors, fever, diarrhea or agitation and consult your doctor if you experience them. Your doctor may discontinue the medicines accordingly.

Severe

Amitriptyline (Oral Route)

Talk to your doctor if you notice any unusual symptoms. Your doctor may adjust the dose if required.

Frequently asked questions

How long does it take for D-Venlor 50 Tablet to work?

The symptoms of depression like change in appetite and sleep patterns may show improvement within 1-2 weeks of starting D-Venlor 50 Tablet. However, it may take about 5-6 weeks to see the full benefits of D-Venlor 50 Tablet.

Is D-Venlor 50 Tablet good for anxiety?

It has been shown to be effective in relieving symptoms of anxiety, though it is not approved for anxiety. It is used in anxiety disorders only when advised by the doctor.

What time of the day is best to take D-Venlor 50 Tablet?

D-Venlor 50 Tablet can be taken either in the morning or in the evening. For best results, take this medicine at the same time each day. This will also help you remember to take it.

Can D-Venlor 50 Tablet be cut?

D-Venlor 50 Tablet should be swallowed whole with water. It should not be cut, chewed, crushed or dissolved. Take it exactly as directed by your doctor.

How can D-Venlor 50 Tablet help treat depression?

D-Venlor 50 Tablet belongs to a class of medicines known as serotonin and norepinephrine reuptake inhibitors (SNRIs). Serotonin and norepinephrine are chemical messengers in the brain which help maintain mental balance. D-Venlor 50 Tablet works by increasing the levels of these two hormones in the brain.

Will I gain weight while taking D-Venlor 50 Tablet?

Weight gain may occur with D-Venlor 50 Tablet, though not in everyone. In case you notice weight gain after taking D-Venlor 50 Tablet, consult your doctor or a nutritionist. Take a low calorie food, including more vegetables and fruits in your diet and exercise regularly.

Will D-Venlor 50 Tablet affect my sex drive?

Taking D-Venlor 50 Tablet may cause a decrease in sexual desire and ability. It may also cause a delay in orgasm and ejaculation and sometimes ejaculation failure. Discuss with your doctor if you experience any of these symptoms while taking D-Venlor 50 Tablet.

Fact Box

Chemical Class

Cyclohexanols

Habit Forming

Therapeutic Class

NEURO CNS

Action Class

Serotonin Norepinephrine Reuptake Inhibitors (SNRIs)

References

Stahl SM, editor. Desvenlafaxine. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 175-80.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 375-77.
Central Drugs Standard Control Organisation (CDSCO). [Accessed 22 Mar. 2019] (online) Available from:
Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Desvenlafaxine. [Updated 2018 Oct 31]. [Accessed 20 Feb. 2020] (online) Available from:
Desvenlafaxine [Prescribing Information]. Philadelphia, PA: Wyeth Pharmaceuticals LLC; 2021. [Accessed 19 Jun. 2023]. (online) Available from:
Desvenlafaxine Extended Release [Product Information Sheet]. Ahmedabad, Gujarat: Torrent Pharmaceuticals Ltd. 2014. [Accessed 20 Feb. 2024] (online) Available from: torrentian.com/pisheet/Upload/PI_Sheet/1536.pdf

User feedback

Patients taking D-Venlor 50 Tablet

Once A Day

75%

Twice A Day

21%

Thrice A Day

Alternate Day

What are you using D-Venlor Tablet for?

Depression

83%

Others

17%

How much was the improvement?

Average

43%

Excellent

36%

Poor

21%

What were the side-effects while using D-Venlor 50 Tablet?

Dizziness

22%

Constipation

11%

Increased sweating

11%

Anxiety

11%

No Side Effect

11%

How do you take D-Venlor Tablet?

With or without food

85%

With food

15%

Please rate D-Venlor 50 Tablet on price

Average

56%

Expensive

39%

Not Expensive

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Cipla Ltd
Address: Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver D-Venlor 50 Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

Lab tests offered by us

Why we need a prescription?

D-Venlor 50 Tablet

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of D-Venlor Tablet

Benefits of D-Venlor Tablet

Side effects of D-Venlor Tablet

How to use D-Venlor Tablet

How D-Venlor Tablet works

All substitutes for D-Venlor 50 Tablet

Defmind 50mg Tablet

Deswave 50mg Tablet

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Moclobemide (Oral Route)

Tranylcypromine (Oral Route)

Selegiline (Oral Route)

Ziprasidone (Oral Route)

Amitriptyline (Oral Route)

Frequently asked questions

How long does it take for D-Venlor 50 Tablet to work?

Is D-Venlor 50 Tablet good for anxiety?

What time of the day is best to take D-Venlor 50 Tablet?

Can D-Venlor 50 Tablet be cut?

How can D-Venlor 50 Tablet help treat depression?

Will I gain weight while taking D-Venlor 50 Tablet?

Will D-Venlor 50 Tablet affect my sex drive?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

References

User feedback

Patients taking D-Venlor 50 Tablet

What are you using D-Venlor Tablet for?

How much was the improvement?

What were the side-effects while using D-Venlor 50 Tablet?

How do you take D-Venlor Tablet?

Please rate D-Venlor 50 Tablet on price

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

In case of any issues, contact us

Lab tests offered by us

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