Comantrel-T Tablet is used alone or in combination with other medicines to treat Parkinson’s disease. It can also be used to treat drug-induced movement disorder. It works by increasing the levels of a chemical called dopamine in the brain, which is important for controlling movement.

Comantrel-T Tablet is also used to prevents and treats influenza infection. The antiviral poperty of the medicine works against the viruses to prevent their and multiplication. Comantrel-T Tablet may be taken with or without food. Take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration as advised by your doctor.

If you have missed a dose, take it as soon as you remember it. You should finish the full course of treatment even if you feel better. It is important that this medication is not stopped suddenly without talking to your doctor. This medicine may put you at a higher risk of having seizures, so it is better to talk to your doctor if you have any history of seizures or taking medication for it.

Some common side effects of Comantrel-T Tablet include nausea, dryness in the mouth, constipation, blurred vision, insomnia (difficulty sleeping), hallucinations, peripheral edema and balance disorder (loss of balance). It may initially cause dizziness and lowering of blood pressure while standing, so rise slowly and do not drive or do anything that requires mental focus until you know how this medicine affects you.

Uses of Comantrel Tablet

Parkinson's disease

Side effects of Comantrel Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Comantrel

Constipation
Hallucination
Dryness in mouth
Fainting
Dizziness
Hypotension (low blood pressure)
Edema (swelling)
Delusion

How to use Comantrel Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Comantrel-T Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Comantrel Tablet works

Comantrel-T Tablet is a dopamine agonist that treats Parkinson's disease. It works by increasing the amount of dopamine, a chemical messenger in the brain which regulates body movements. It also has an antiviral property. It works against viruses to prevent their growth and multiplication. It also appears to restricts the viruses to release infectious chemicals (viral nucleic acid) to enter into the body. Thus, it prevents and treats influenza infection.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Comantrel-T Tablet.

Pregnancy

CONSULT YOUR DOCTOR

Comantrel-T Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Comantrel-T Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

UNSAFE

Comantrel-T Tablet may cause side effects which could affect your ability to drive.

Kidney

CAUTION

Comantrel-T Tablet should be used with caution in patients with kidney disease. Dose adjustment of Comantrel-T Tablet may be needed. Please consult your doctor.
Use of Comantrel-T Tablet is not recommended in patients with severe kidney disease.

Liver

CAUTION

Comantrel-T Tablet should be used with caution in patients with liver disease. Dose adjustment of Comantrel-T Tablet may be needed. Please consult your doctor.
It may cause a transient increase in liver enzymes.

What if you forget to take Comantrel Tablet?

If you miss a dose of Comantrel-T Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.\n

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Comantrel-T Tablet

₹9.21/Tablet

Parkitidin Tablet

Sun Pharmaceutical Industries Ltd

₹15.9/tablet

73% costlier

Ensorex 100mg Tablet

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₹16.27/tablet

77% costlier

Amantex Tablet

Intas Pharmaceuticals Ltd

₹15.53/tablet

69% costlier

Amantrel Tablet

Cipla Ltd

₹17.4/tablet

89% costlier

Manotrel 100mg Tablet

Cmg Biotech Pvt Ltd

₹10.8/tablet

17% costlier

Quick tips

It can be taken with or without food.
It may cause blurring of vision or affect mental ability. Do not drive or do anything requiring concentration until you know how it affects you.
To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
Do not take extra medicine to make up for the missed dose.
It may put you at a higher risk of having seizures. Talk to your doctor if you have a history of seizures or are taking medication for it.
Inform your doctor if you notice an urge to gamble, increased sexual urges, binge eating, or uncontrolled spending.
Do not stop taking the medication suddenly without talking to your doctor.

Fact Box

Chemical Class

Synthetic Tricyclic Amine Derivative

Habit Forming

Therapeutic Class

NEURO CNS

Action Class

Dopamine facilitator

Interaction with drugs

Taking Comantrel with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Memantine (Oral Route) Moderate

If taken together, Amantadine may decrease the absorption of Memantine. Do not consume Memantine with Amantadine. If concurrent use is essential, your doctor may monitor your trea... More

Bupropion (Oral Route) Moderate

Concurrent use may cause increased side effects such as nausea, vomiting, excitement, restlessness, and postural tremor. Careful consideration is advised when taking Bupropion wit... More

Olanzapine (Injection Route) Moderate

Concurrent use may increase the risk of heat stroke and constipation. Amantadine may reduce efficacy of Olanzapine. If concurrent use is essential, watch out for symptoms such as c... More

Pimozide (Oral Route) Moderate

Concurrent use may increase the risk of heat stroke and constipation. Amantadine may reduce efficacy of Pimozide. If concurrent use is essential, watch out for symptoms such as con... More

Prochlorperazine (Oral Route) Moderate

Concurrent use may increase the risk of heat stroke and constipation. Amantadine may reduce efficacy of Prochlorperazine. If concurrent use is essential, watch out for symptoms suc... More

View all drug interactions

Patient concerns

Parkinson's disease tremors ,Insomnia.

Dr. Ravi Shankar M.

Ayurveda

Use Dhanadanayanadi kashayam 15ml twice a day with 15 ml water before food and Zandopa 10 grams twice a day witk milk after food and Tab Dhanvantari Vati 1-0-1 after food for 2 months

Parkinson's disease for 25 yrs. Taking allopathy Suggestions needed

Dr. Deepak Kumar Soni

Ayurveda

Kindly consult to any good Ayuvedic Panchkarma center. Panchkarma therapy will give you some result .

My father has parkinson's disease from last 12 year. In last 2012 he got severe pneumonia and has been admitted in AIIMS .He was treated with various antibiotics.he came out but got bed ridden after that.From last few year he just sit on his own. he is currently taking bexol 1mg three times, syndopa 125 plus 3 times, ropark XL 3 times.now from few year he got hallucination and cound not sleep in night and constantly talking in night(Some Nights not always).During his stay in AIIMS Dr. prescribed quetiapine 12.5 mg which he is not currently taking.please advice some medicien so that he atleast can sleep at night.

Dr. Vikas Sharma

Neurology

Start Oleanz 2.5 mg at nite

FAQs

Can Comantrel-T Tablet get you high?

The use of Comantrel-T Tablet may cause impulse control disorders in which you may have strong urges to gamble, increased sexual urges, intense urges to spend money, binge eating, and other intense urges. Additionally, there is the inability to control these urges. If such symptoms are experienced then dose reduction or tapered discontinuation should be considered.

Does Comantrel-T Tablet affect fertility?

No, Comantrel-T Tablet is not known to affect fertility in humans.

Does Comantrel-T Tablet affect fertility?

No, Comantrel-T Tablet is not known to affect fertility in humans.

Can Comantrel-T Tablet get you high?

Is Comantrel-T Tablet a dopamine agonist?

Yes, Comantrel-T Tablet is a dopamine agonist. Dopamine is needed to control movements in the brain. Comantrel-T Tablet works by increasing the amount of dopamine, thereby helping in controlling the movements in Parkinson’s disease.

Does Comantrel-T Tablet cause constipation?

Yes, constipation is a common side effect of Comantrel-T Tablet, though it does not occur in everyone. Consult your doctor or a dietician if constipation persists and is troublesome.

Does Comantrel-T Tablet cause fatigue?

Yes, Comantrel-T Tablet causes fatigue and sleepiness which may affect some patients’ ability to drive and operate machinery safely.

Can I take Comantrel-T Tablet any time during the day? Should the dose be taken before meal?

Yes, Comantrel-T Tablet can be taken at any time during the day, with or without food. Try to take the medicine at about the same time each day, as directed by your doctor. Taking your medicine at the same time each day will have the best effect. It will also help you to remember when to take your medicine.

Is Comantrel-T Tablet used for pain?

Though it is not an approved use, Comantrel-T Tablet has been shown to be effective in relieving pain related to nerve disorder. Comantrel-T Tablet is a prescription medicine, and you should take it for relief of pain only if advised by the doctor.

What happens when I stop taking Comantrel-T Tablet?

Do not stop taking this medicine or lower the dose without first checking with your doctor. If required, your doctor will gradually reduce the amount you take each day before stopping it completely. Abruptly stopping Comantrel-T Tablet may result in worsening of Parkinsonism. It may also cause delirium, agitation, delusions, hallucinations, paranoid reaction, stupor, anxiety, depression, or slurred speech.

Can Comantrel-T Tablet cause weight loss?

Decreased weight and body mass index may occur with continued Comantrel-T Tablet usage. If you have any concerns regarding weight loss consult your doctor or a nutritionist.

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

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Standaert DG, Roberson ED. Treatment of Central Nervous System Degenerative Disorders. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 619.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 48-49.
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Drugs.com. Amantadine Pregnancy and Breastfeeding Warnings. [Accessed 19 Mar. 2019] (online) Available from:
Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Amantadine. [Updated 2018 Oct 31]. [Accessed 19 Feb. 2020] (online) Available from:
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Marketer details

Name: Consern Pharma Limited

Address: Consern Pharma Private Limited, Kuljive Mahajan(Mg. Director), Rural Focal Point, V.P.O. Tibba, Ludhiana - 141120, Punjab, India

Country of origin: India

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