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Cletus 50mg Tablet

Written By Dr. Syeda Aafia, MBA, BDS
Reviewed By Dr. Rajeev Sharma, MBA, MBBS
Last updated on 17 Dec 2025 | 03:02 PM (IST)
Cletus 50mg Tablet is used in the treatment of pain in the legs due to insufficient blood flow (intermittent claudication). It also helps in reducing cramping, numbness, or weakness in the legs that occurs on walking in such patients.
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General Information

The content is shown in English
Cletus 50mg Tablet image
Cletus 50mg Tablet image

Product introduction

Cletus 50mg Tablet should be taken regularly as advised by the doctor. You should take it on an empty stomach and at a fixed time. This medicine should not be stopped abruptly without consulting the doctor.

It may cause side effects like headache, vomiting, edema, diarrhea, dizziness, palpitation, abdominal pain, abnormal stools, and edema. Use of this medicine may increase your risk of bleeding. Let your doctor know immediately if you see a pinpoint rash or blood in your vomits, urine, or stool.

This medicine may not be suitable for some people. You must inform the doctor if you are suffering from any liver or kidney disease. Also, let your doctor know about all the other medications that you are using regularly. This medicine is not usually recommended during pregnancy or breastfeeding, so always consult your doctor before taking it.

Uses of Cletus Tablet

Benefits of Cletus Tablet

Treatment of Intermittent claudication
Intermittent claudication refers to muscle pain on mild exertion (ache, cramp, numbness, or sense of fatigue), classically in the calf muscle, which occurs during exercise or even walking, and it gets better with a short period of rest. Cletus 50mg Tablet helps relieve this pain in the legs that is caused due to disturbed blood supply in the legs. It helps prevent the formation of blood clots, improves blood flow, and maintains the free-flowing of blood in your body. Keep taking Cletus 50mg Tablet as prescribed by the doctor to get maximum benefit.

Side effects of Cletus Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Cletus
  • Headache
  • Palpitations
  • Abnormal stool
  • Diarrhea
  • Dizziness
  • Inflammation of the nose
  • Bleeding disorder
  • Edema (swelling)
  • Increased heart rate
  • Abdominal pain

How to use Cletus Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Cletus 50mg Tablet is to be taken on an empty stomach.

How Cletus Tablet works

Cletus 50mg Tablet widens the blood vessels and decreases the stickiness of the platelets, thereby increasing the blood flow to the lower limbs.

Quick tips

  • Take it at least half an hour before or two hours after breakfast and dinner.
  • It may take up to 12 weeks before your symptoms improve. Keep using the medication as directed.
  • Consult your doctor, if your symptoms do not improve after 4 weeks of treatment.
  • It may cause dizziness. Don't drive or do anything that requires mental focus until you know how it affects you.
  • Do not take it if you have heart failure, persistent chest pain at rest, or have had a heart attack or any heart surgery in the last six months. 

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Cletus 50mg Tablet. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Cletus 50mg Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.
Breast feeding

Breast feeding

UNSAFE
Cletus 50mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving

Driving

CONSULT YOUR DOCTOR
It is not known whether Cletus 50mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
Kidney

Kidney

SAFE IF PRESCRIBED
Cletus 50mg Tablet is safe to use in patients with kidney disease. No dose adjustment is recommended.
Liver

Liver

CONSULT YOUR DOCTOR
There is limited data available on the use of Cletus 50mg Tablet in patients with liver disease.

Interaction with drugs

Taking Cletus with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Severe

Streptokinase (Injection Route)

Inform your doctor if you notice any signs of bleeding (bruising, bleeding gums, blood in stool/vomit/urine).
Severe

Fondaparinux (Injection Route)

If concurrent use is essential, watch out for bleeding and consult your doctor immediately.
Severe

Pimozide (Oral Route)

Do not consume Cilostazol with Pimozide. Cilostazol may raise blood levels of Pimozide.
Severe

Urokinase (Injection Route)

Inform your doctor if you notice any signs of bleeding (bruising, bleeding gums, blood in stool/vomit/urine).
Severe

Bemiparin (Injection Route)

Do not consume Bemiparin with Cilostazol. If concurrent use is essential, watch out for bleeding and consult your doctor immediately. They may monitor your treatment closely.

Frequently asked questions

Yes, Cletus 50mg Tablet increases the risk of bleeding. Always be careful while doing activities that may cause an injury or bleeding. Tell your doctor immediately if you notice any abnormal bruising or bleeding.
Cletus 50mg Tablet reduces your risk of developing blood clots in the blood vessels of your leg, lungs, heart, and brain. You may not feel any difference after taking Cletus 50mg Tablet. However, keep taking this medicine as prescribed by your doctor because you will still be getting its full benefits.
You should continue to take Cletus 50mg Tablet for as long as your doctor recommends. Your doctor will assess your progress after 3 months of treatment and may recommend you to discontinue Cletus 50mg Tablet if it is not working for you. This medicine helps to control your condition but does not cure it. It is important to keep taking your medicine even if you feel well.
The improvement is not seen immediately. Your symptoms may start improving after 2-4 weeks of starting the treatment. However, it may take about 12 weeks to notice the full benefits of the medicines.
Yes, if a patient is scheduled to undergo surgery, then Cletus 50mg Tablet should be stopped 5 days before the surgery. The reason being, Cletus 50mg Tablet increases the risk of bleeding and may lead to excessive bleeding during surgery.
Cletus 50mg Tablet should not be given to heart failure patients of any severity because it may worsen heart failure further. Medicines having a similar effects (phosphodiesterase inhibitor III) have decreased the lifespan of the patients, and therefore, it is an absolute no for heart failure patients.
Since Cletus 50mg Tablet widens blood vessels, it generally decreases blood pressure. Therefore, if you are taking medicines that lower blood pressure, you should be careful. Taking Cletus 50mg Tablet with other blood pressure-lowering medicines may decrease your blood pressure to very low levels. Track your blood pressure regularly, and consult your doctor if dose adjustment is required. Cletus 50mg Tablet has also been reported to increase blood pressure and the reason for which is not known.

Fact Box

Chemical Class

Hydroquinolones

Habit Forming

No

Therapeutic Class

CARDIAC

Action Class

Phosphodiesterase III Inhibitors (PVD)

References

  1. Michel T, Hoffman BB. Treatment of Myocardial Ischemia and Hypertension. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 765.
  2. Zehnder JL. Drugs Used in Disorders of Coagulation. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 599.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 270.
  4. Gersh BJ, Opie LH. Which Therapy for WHich Condition? Inhibitors of the Renin-Angiotensin-Aldosterone System. In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. p. 528.
  5. Cilostazol. Pabianice, Poland: Pabianickie Zakłady Farmaceutyczne Polfa S.A.; 2014. [Accessed 24 Jan. 2019] (online) Available from:
  6. Cilostazol. Tokushima, Japan: Otsuka Pharmaceutical Co. Ltd. [Accessed 15 Mar. 2019] (online) Available from:
  7. Central Drugs Standard Control Organisation (CDSCO). Cilostazol. [Accessed 15 Mar. 2019] (online) Available from:
  8. Balinski AM, Preuss CV. Cilostazol. [Updated 2023 Mar 27]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023. [Accessed 16 Jun. 2023] (online) Available from:
  9. Cilostazol [Prescrining Information]. Parsippany, NJ: Teva Pharmaceuticals; 2022. [Accessed 16 Jun. 2023] (online) Available from:
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User feedback

Twice A Day
60%
Once A Day
40%
Intermittent claudication
100%
Excellent
100%
No Side Effect
100%
Empty stomach
100%
Not Expensive
100%
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Novartis India Ltd
Address: Sandoz House, Shiv Sagar Estate, Worli Mumbai -400 018, India

Vendor Details

Country of origin: India
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