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Urokinase

INFORMATION

Uses

Urokinase is used in the treatment of heart attack, pulmonary embolus (blood clot in lungs) and ischemic stroke (decreased blood supply to brain).

How it works

Urokinase dissolves the harmful blood clot in the blood vessels

Common side effects

Liver enzyme increased, Nose bleed, Bleeding from puntured wound, Blood clotting disorder, Blood in urine, Chills, Shivering, Decreased haematocrit level, Fever, Bleeding at the puncture site, Brain haemorrhage, Gastrointestinal bleeding, Stroke, Tearing of artery wall

AVAILABLE MEDICINE

Expert advice

  • Special care should be taken while using urokinase if you recently have had bleeding from stomach or intestines, had surgery or had given blood recently, had heart problems, have severe blood vessel in the brain or are above 75 years of age.
  • Inform your doctor if you are taking medication like heparin or other anticoagulants, aspirin, non-steroidal anti-inflammatory agents (NSAIDs), dipyridamole or dextrans.
  • Avoid taking aspirin or ibuprofen to treat a fever after you have received urokinase as it may increase your risk of bleeding.
  • Avoid activities that may increase your risk of bleeding or injury.

Frequently asked questions

Urokinase

Q.What is urokinase made from/ found/ produced?
Urokinase is man-made product developed using a protein that occurs naturally in the kidneys. It is obtained from human neonatal kidney cells grown in tissue culture.


Content on this page was last updated on 30 November, 2016, by Dr. Varun Gupta (MD Pharmacology)