Zilast 50 Tablet is used in the treatment of pain in the legs due to insufficient blood flow (intermittent claudication). It also helps in reducing cramping, numbness, or weakness in the legs that occurs on walking in such patients.

Zilast 50 Tablet should be taken regularly as advised by the doctor. You should take it on an empty stomach and at a fixed time. This medicine should not be stopped abruptly without consulting the doctor.

It may cause side effects like headache, nausea, vomiting, edema, diarrhea, dizziness, palpitation, abdominal pain, abnormal stools, flatulence, and edema. Use of this medicine may increase your risk of bleeding. Let your doctor know immediately if you see a pinpoint rash or blood in your vomits, urine, or stool.

This medicine may not be suitable for some people. You must inform the doctor if you are suffering from any liver or kidney disease. Also, let your doctor know about all the other medications that you are using regularly. This medicine is not usually recommended during pregnancy or breastfeeding, so always consult your doctor before taking it.

Uses of Zilast Tablet

Treatment of Intermittent claudication

Benefits of Zilast Tablet

In Treatment of Intermittent claudication

Intermittent claudication refers to muscle pain on mild exertion (ache, cramp, numbness, or sense of fatigue), classically in the calf muscle, which occurs during exercise or even walking, and it gets better with a short period of rest. Zilast 50 Tablet helps relieve this pain in the legs that is caused due to disturbed blood supply in the legs. It helps prevent the formation of blood clots, improves blood flow, and maintains the free-flowing of blood in your body. Keep taking Zilast 50 Tablet as prescribed by the doctor to get maximum benefit.

Side effects of Zilast Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Zilast

Headache
Palpitations
Abnormal stool
Diarrhea
Dizziness
Nausea
Bleeding disorder
Edema (swelling)
Flatulence

How to use Zilast Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Zilast 50 Tablet is to be taken empty stomach.

How Zilast Tablet works

Zilast 50 Tablet widens the blood vessels and decreases the stickiness of the platelets, thereby increasing the blood flow to the lower limbs.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Zilast 50 Tablet. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Zilast 50 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Zilast 50 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

UNSAFE

Zilast 50 Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Zilast 50 Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Zilast 50 Tablet may be needed. Please consult your doctor.

Liver

CAUTION

Zilast 50 Tablet should be used with caution in patients with liver disease. Dose adjustment of Zilast 50 Tablet may be needed. Please consult your doctor.
Use of Zilast 50 Tablet is not recommended in patients with moderate and severe liver disease as the information available in these patients is limited.

What if you forget to take Zilast Tablet?

If you miss a dose of Zilast 50 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

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Quick tips

Take it at least half an hour before or two hours after breakfast and dinner.
It may take up to 12 weeks before your symptoms improve. Keep using the medication as directed.
Consult your doctor, if your symptoms do not improve after 4 weeks of treatment.
It may cause dizziness. Don't drive or do anything that requires mental focus until you know how it affects you.
Do not take it if you have heart failure, persistent chest pain at rest, or have had a heart attack or any heart surgery in the last six months.

Fact Box

Chemical Class

Quinoline & tetrazole derivative

Habit Forming

Therapeutic Class

CARDIAC

Action Class

Phosphodiesterase III Inhibiotrs (PVD)

Interaction with drugs

Taking Zilast with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Clotrimazole

Brand(s): Clowil, Odis, Kamestin

LIFE-THREATENING

Esomeprazole

Brand(s): Esodoc, Styx, Escid

LIFE-THREATENING

Fluconazole

Brand(s): EF Z, Rocflu, Welcon

LIFE-THREATENING

Itraconazole

Brand(s): Indizole

LIFE-THREATENING

View all interactions

Patient concerns

What is medicine for claudication

Dr. Jyoti Kapoor Madan

Psychiatry

Please consult a vascular surgeon

There is coldness in my feet and it is causing pain especially below knees Please help me

Dr. Pushkar Mani

Physician

It could be claudication, so kindly consult Surgeon

Intermittent fever and rashes on skin allover

Dr. Gopal Bansilal Samdani

Paediatrics

There are many underlying causes of Patient?s symptoms. Different cause needs different treatment. Specific treatment cannot be given unless we establish exact underlying cause. Final and perfect diagnosis cannot be done without doing clinical examination of patient. Please consult me or any other Paediatrician. will take detail history and will examine patient in detail. All information will be used to determine exact underlying cause of problem. Depending upon cause will give opinion and prescribe you treatment. At time may ask you relevant investigations if necessary.

User feedback

Patients taking Zilast 50 Tablet

Twice A Day

53%

Once A Day

40%

Thrice A Day

What are you using Zilast Tablet for?

Intermittent *

50%

Peripheral va*

25%

Others

25%

*Intermittent claudication, Peripheral vascular disease

How much was the improvement?

Poor

100%

What were the side-effects while using Zilast 50 Tablet?

No Side Effec*

100%

*No Side Effect

How do you take Zilast Tablet?

Empty stomach

100%

Please rate Zilast 50 Tablet on price

Not Expensive

100%

FAQs

Q. Can the use of Zilast 50 Tablet increase the risk of bleeding?

Yes, Zilast 50 Tablet increases the risk of bleeding. Always be careful while doing activities that may cause an injury or bleeding. Tell your doctor immediately if you notice any abnormal bruising or bleeding.

Q. When will I feel better after taking Zilast 50 Tablet?

Zilast 50 Tablet reduces your risk of developing blood clots in the blood vessels of your leg, lungs, heart, and brain. You may not feel any difference after taking Zilast 50 Tablet. However, keep taking this medicine as prescribed by your doctor because you will still be getting its full benefits.

Q. For how long should I take Zilast 50 Tablet?

You should continue to take Zilast 50 Tablet for as long as your doctor recommends. Your doctor will assess your progress after 3 months of treatment and may recommend you to discontinue Zilast 50 Tablet if it is not working for you. This medicine helps to control your condition but does not cure it. It is important to keep taking your medicine even if you feel well.

Q. After how many days of taking Zilast 50 Tablet will I start feeling better?

The improvement is not seen immediately. Your symptoms may start improving after 2-4 weeks of starting the treatment. However, it may take about 12 weeks to notice the full benefits of the medicines.

Q. Should Zilast 50 Tablet be stopped before surgery?

Yes, if a patient is scheduled to undergo surgery, then Zilast 50 Tablet should be stopped 5 days before the surgery. The reason being, Zilast 50 Tablet increases the risk of bleeding and may lead to excessive bleeding during surgery.

Q. Why is Zilast 50 Tablet considered harmful for heart failure patients?

Zilast 50 Tablet should not be given to heart failure patients of any severity because it may worsen heart failure further. Medicines having a similar effects (phosphodiesterase inhibitor III) have decreased the lifespan of the patients, and therefore, it is an absolute no for heart failure patients.

Q. Does Zilast 50 Tablet raise blood pressure or decrease blood pressure?

Since Zilast 50 Tablet widens blood vessels, it generally decreases blood pressure. Therefore, if you are taking medicines that lower blood pressure, you should be careful. Taking Zilast 50 Tablet with other blood pressure-lowering medicines may decrease your blood pressure to very low levels. Track your blood pressure regularly, and consult your doctor if dose adjustment is required. Zilast 50 Tablet has also been reported to increase blood pressure and the reason for which is not known.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Michel T, Hoffman BB. Treatment of Myocardial Ischemia and Hypertension. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 765.
Zehnder JL. Drugs Used in Disorders of Coagulation. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 599.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 270.
Gersh BJ, Opie LH. Which Therapy for WHich Condition? Inhibitors of the Renin-Angiotensin-Aldosterone System. In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. p. 528.
Cilostazol. Pabianice, Poland: Pabianickie Zakłady Farmaceutyczne Polfa S.A.; 2014. [Accessed 24 Jan. 2019] (online) Available from:
Cilostazol. Budapest, Hungary: Egis Pharmaceuticals PLC. [Accessed 15 Mar. 2019] (online) Available from:
Cilostazol. Tokushima, Japan: Otsuka Pharmaceutical Co. Ltd. [Accessed 15 Mar. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). Cilostazol. [Accessed 15 Mar. 2019] (online) Available from:

Manufacturer/Marketer address

142 AB, Kandivli Industrial Estate, Kandivli (West), Mumbai - 400 067, Maharashtra

Country of origin: India

Expires on or after: April, 2022

A licensed vendor partner from your nearest location will deliver Zilast 50 Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

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