Bendawel 100mg Injection

Bendamustine (100mg)

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Bendawel 100mg Injection is used to treat chronic lymphocytic leukaemia (CLL) and certain slow-growing B-cell non-Hodgkin lymphomas (NHL) that have progressed during or within six months of rituximab treatment. It damages the DNA of cancer cells, slowing their growth. It is given as an infusion into a vein.

Written By Dr. Nikita Saini, MBA, MDS,
Reviewed By Dr. Dheeraj Kumar Sharma, PhD, M.Pharm,
Last updated on 03 Nov 2026 | 08:20 PM (IST)

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General Information

Contains

Bendamustine (100mg)

Marketer

Getwell Pharma (I) Pvt Ltd

Storage

Store below 25°C

The content is shown in English

Product introduction

Bendawel 100mg Injection is given as an infusion into a vein under the supervision of a doctor and should not be self-administered. Your doctor will decide the dose and treatment schedule based on your condition. The schedule may change depending on your response and side effects. Do not miss your scheduled infusions unless your doctor advises you to. Taking too much can cause serious side effects. It may take several weeks or months for you to see or feel the benefits, but do not stop treatment unless your doctor tells you to.

Common side effects of this medicine include low blood cell counts, tiredness, nausea, vomiting, and fever. Some people may also develop infections or serious reactions. If you have a fever, unusual bleeding, breathlessness, or a severe skin rash, contact your doctor immediately. Your doctor may suggest ways to manage side effects.

Inform your doctor if you have a history of bleeding disorders, heart, kidney or liver disease, radiation treatment, or any infection. Tell your doctor about all medicines you use. This medicine can lower blood cell counts and increase the risk of infections and bleeding. Your doctor may check your blood counts and kidney and liver function during treatment. This medicine can harm an unborn baby. Women and men should use effective contraception during treatment and for the period advised by their doctor.

Uses of Bendawel Injection

Non-Hodgkin lymphoma (NHL)
Blood cancer (Chronic lymphocytic leukemia)
Blood cancer (Acute lymphocytic leukemia)
Multiple myeloma

Benefits of Bendawel Injection

Non-Hodgkin lymphoma (NHL)
Non-Hodgkin lymphoma (NHL) is a cancer of white blood cells that help fight infections. Bendawel 100mg Injection is used for certain slow-growing B-cell lymphomas that have progressed during or within six months of treatment with rituximab or a rituximab-containing regimen. It damages the DNA of cancer cells, helping slow their growth. Avoid crowds and wash your hands often to reduce the risk of infection. Drink plenty of fluids unless your doctor advises otherwise.

Blood cancer (Chronic lymphocytic leukemia)
Bendawel 100mg Injection helps treat chronic lymphocytic leukaemia by damaging the DNA of cancerous white blood cells, which prevents them from growing and multiplying. This helps reduce the number of abnormal leukaemia cells and control the progression of the disease.

Blood cancer (Acute lymphocytic leukemia)
Bendawel 100mg Injection helps treat chronic lymphocytic leukemia by damaging the DNA of cancerous white blood cells, which prevents them from growing and multiplying. This helps reduce the number of abnormal leukemia cells, control the progression of the disease.

Multiple myeloma
Multiple myeloma is a type of blood cancer that affects plasma cells, a type of white blood cell found in the bone marrow. It can cause bone pain, weakness, frequent infections, and kidney problems. Bendawel 100mg Injection is used with prednisone to treat certain patients above 65 years of age with newly diagnosed multiple myeloma who are not eligible for a stem cell transplant and cannot receive thalidomide or bortezomib-based treatment due to nerve damage. It works by damaging the DNA of cancer cells, preventing them from growing and multiplying. This helps control the disease and slow its progression.

Side effects of Bendawel Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Bendawel

Decreased white blood cell count (lymphocytes)
Low blood platelets
Cough
Breathlessness
Decreased hemoglobin

How to use Bendawel Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Bendawel Injection works

Bendawel 100mg Injection is an anti-cancer medicine. It damages the DNA of cancer cells, preventing them from growing and multiplying.

All substitutes for Bendawel 100mg Injection

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Bendawel 100mg Injection is given as an infusion into a vein under the supervision of a doctor.
Do not miss your scheduled treatment sessions and follow the dosing schedule advised by your doctor.
Your doctor will regularly monitor your blood cell counts, as Bendawel 100mg Injection can lower white blood cells, red blood cells, and platelets. This may increase the risk of infections, tiredness, or bleeding.
Stay adequately hydrated during treatment unless your doctor has advised you to restrict fluids.
Tell your doctor about all medicines, supplements, and vaccines you are taking or planning to receive. Live vaccines may not be safe during treatment with Bendawel 100mg Injection.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Bendawel 100mg Injection. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Bendawel 100mg Injection is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

UNSAFE

Bendawel 100mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving

UNSAFE

Bendawel 100mg Injection may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CONSULT YOUR DOCTOR

There is limited data available on the use of Bendawel 100mg Injection in patients with kidney disease. Please consult your doctor.

Liver

CONSULT YOUR DOCTOR

There is limited data available on the use of Bendawel 100mg Injection in patients with liver disease.

Interaction with drugs

Taking Bendawel with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Life-threatening

Pegfilgrastim (Injection Route)

Do not consume Bendamustine from 14 days before until 24 days after taking Pegfilgrastim. Please consult your doctor.

Life-threatening

Sargramostim (Injection Route)

Do not consume Bendamustine from 1 day before until 1 day after taking Sargramostim. Please consult your doctor.

Life-threatening

Lenograstim (Injection Route)

Do not consume Lenograstim from 24 hours before until 24 hours after undergoing cytotoxic chemotherapy.

Severe

Filgrastim (Injection Route)

Do not consume Filgrastim from 24 hours before and until 24 hours after taking Bendamustine.

Severe

Ciclosporin (Oral Route)

If concurrent use is essential, watch out for bleeding and symptoms such as headache, mouth ulcers or weakness and consult your doctor if you experience them. They may adjust the doses as per the observations.

Frequently asked questions

Is Bendawel 100mg Injection safe?

Bendawel 100mg Injection can cause serious side effects even when given at the prescribed dose. Your doctor may monitor blood counts and signs of infection during treatment. Tell your doctor immediately if you develop fever, unusual bleeding, or a severe rash.

How does Bendawel 100mg Injection work?

Bendawel 100mg Injection works by damaging the DNA of cancer cells, making it harder for them to grow and multiply.

Is Bendawel 100mg Injection a vesicant?

Bendawel 100mg Injection can damage tissue if the infusion leaks outside the vein. Tell your doctor or nurse immediately if you feel pain, burning, or swelling around the infusion site.

Does Bendawel 100mg Injection cause hair loss/constipation?

Hair loss and constipation may occur during treatment with Bendawel 100mg Injection. Tell your doctor if these symptoms bother you.

Fact Box

Chemical Class

Benzimidazoles

Habit Forming

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Alkylating Agents

Related lab tests

Albumin/Globulin Ratio, Serum

Calcium

Complete Blood Count

Kidney Function Test

Peripheral Smear Examination

References

Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1684.
Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 942, 944.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 131-32.
Bendamustine hydrochloride monohydrate. Guildford, Surrey: Zentiva; 2015 [revised 29 Aug. 2018]. [Accessed 26 Mar. 2019] (online) Available from:
Bendamustine hydrochloride. Lake Forest, IL: Hospira, Inc.; 2008 [revised May 2016]. [Accessed 26 Mar. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:
Bendamustine hydrochloride. Deerfield, IL: Baxter Healthcare Corporation; 2024. [Accessed 26 Sep. 2026] (online). Available from:

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Getwell Pharma (I) Pvt Ltd
Address: 464, Udyog Vihar, Phase-V Sector 19, Gurugram Haryana 122016

Vendor Details

Country of origin: India

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Anti Neoplastics

Alkylating Agents

Bendawel 100mg Injection

Bendawel 100mg Injection

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Bendawel Injection

Benefits of Bendawel Injection

Side effects of Bendawel Injection

How to use Bendawel Injection

How Bendawel Injection works

All substitutes for Bendawel 100mg Injection

Purplz 100mg Injection

Bendit 100mg Injection

Bizisa Injection

Adben 100mg Injection

Bendamax 100 Injection

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Pegfilgrastim (Injection Route)

Sargramostim (Injection Route)

Lenograstim (Injection Route)

Filgrastim (Injection Route)

Ciclosporin (Oral Route)

Frequently asked questions

Is Bendawel 100mg Injection safe?

How does Bendawel 100mg Injection work?

Is Bendawel 100mg Injection a vesicant?

Does Bendawel 100mg Injection cause hair loss/constipation?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Albumin/Globulin Ratio, Serum

Calcium

Complete Blood Count

Kidney Function Test

Peripheral Smear Examination

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

Related/Popular tests