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Bendit 100mg Injection

Bendamustine (100mg)

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Bendit 100mg Injection is used to treat cancer of the lymphatic system such as Non-Hodgkin's Lymphoma (NHL). It may also be used to treat other types of cancer as determined by your doctor. It can be used alone, or together with certain other medicines as part of combination chemotherapy.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 29 Apr 2026 | 01:02 PM (IST)

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General Information

Contains

Bendamustine (100mg)

Marketer

Natco Pharma Ltd

Storage

Store below 25°C

The content is shown in English

Product introduction

Bendit 100mg Injection is given as an injection into vein under the supervision of a doctor and should not be self-administered. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

The most common side effects of this medicine include anemia (low number of red blood cells), decreased white blood cell count, infection, fatigue, nausea, and vomiting. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them.

Inform your doctor if you have a medical history, of bleeding disorders, heart or liver disease, radiation treatment or any infection. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is known to reduce the number of blood cells in your blood thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with kidney, liver and heart function during treatment with this medicine. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Uses of Bendit Injection

Benefits of Bendit Injection

Non-Hodgkin lymphoma (NHL)
Non-Hodgkin's lymphoma is a cancer of the white blood cells in our body, also called mantle-cell lymphoma. White blood cells are those cells that help us to fight infections. Bendit 100mg Injection helps to restrict cancer growth and also blocks the action of other chemicals that are required for cancer growth and further spread. Avoid being in crowds and wash your hands often to prevent any infections. Have plenty of fluids, unless otherwise advised by the doctor not to.

Side effects of Bendit Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Bendit

Anemia (low number of red blood cells)
Decreased white blood cell count
Infection
Fatigue
Nausea
Fever
Vomiting
Low blood platelets
Mucosal inflammation

How to use Bendit Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Bendit Injection works

Bendit 100mg Injection is an anti-cancer medication. It works by damaging the genetic material (DNA and RNA) of the cancer cells. This stops their growth and multiplication.

All substitutes for Bendit 100mg Injection

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Bendit 100mg Injection is given as an injection into vein under the supervision of a doctor.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Bendit 100mg Injection. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Bendit 100mg Injection is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

CAUTION

Bendit 100mg Injection should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.

Driving

CONSULT YOUR DOCTOR

It is not known whether Bendit 100mg Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.

Kidney

CONSULT YOUR DOCTOR

There is limited data available on the use of Bendit 100mg Injection in patients with kidney disease. Please consult your doctor.

Liver

CONSULT YOUR DOCTOR

There is limited data available on the use of Bendit 100mg Injection in patients with liver disease.

Interaction with drugs

Taking Bendit with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Life-threatening

Pegfilgrastim (Injection Route)

Do not consume Bendamustine from 14 days before until 24 days after taking Pegfilgrastim. Please consult your doctor.

Life-threatening

Sargramostim (Injection Route)

Do not consume Bendamustine from 1 day before until 1 day after taking Sargramostim. Please consult your doctor.

Life-threatening

Lenograstim (Injection Route)

Do not consume Lenograstim from 24 hours before until 24 hours after undergoing cytotoxic chemotherapy.

Severe

Filgrastim (Injection Route)

Do not consume Filgrastim from 24 hours before and until 24 hours after taking Bendamustine.

Severe

Ciclosporin (Oral Route)

If concurrent use is essential, watch out for bleeding and symptoms such as headache, mouth ulcers or weakness and consult your doctor if you experience them. They may adjust the doses as per the observations.

Frequently asked questions

Is Bendit 100mg Injection safe?

Bendit 100mg Injection is safe if used at prescribed doses for the prescribed duration as advised by your doctor.

How does Bendit 100mg Injection work?

Bendit 100mg Injection works by destroying the DNA, thus killing the existing cancer cells and also preventing the growth and spread of new cancer cells.

Is Bendit 100mg Injection a vesicant?

Bendit 100mg Injection has vesicant properties and can seriously damage skin and underlying fat if leaks during administration.

Does Bendit 100mg Injection cause hair loss/constipation?

Yes, hair loss and constipation are the common side effects of Bendit 100mg Injection.

Does Bendit 100mg Injection cross blood brain barrier?

Yes, Bendit 100mg Injection crosses the blood brain barrier, and may be used to treat cancers spread to the brain.

Fact Box

Chemical Class

Benzimidazoles

Habit Forming

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Alkylating Agents

Related lab tests

Albumin/Globulin Ratio, Serum

Calcium

Complete Blood Count

Kidney Function Test

Peripheral Smear Examination

References

Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1684.
Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 942, 944.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 131-32.
Bendamustine hydrochloride monohydrate. Guildford, Surrey: Zentiva; 2015 [revised 29 Aug. 2018]. [Accessed 26 Mar. 2019] (online) Available from:
Bendamustine hydrochloride. Lake Forest, IL: Hospira, Inc.; 2008 [revised May 2016]. [Accessed 26 Mar. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Natco Pharma Ltd
Address: Natco House, Road No.2, Banjara Hills, Hyderabad-500 034, India

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Bendit 100mg Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

Lab tests offered by us

Why we need a prescription?

Bendit 100mg Injection

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Bendit Injection

Benefits of Bendit Injection

Side effects of Bendit Injection

How to use Bendit Injection

How Bendit Injection works

All substitutes for Bendit 100mg Injection

Purplz 100mg Injection

Bizisa Injection

Adben 100mg Injection

Bendamax 100 Injection

Acodamust Injection

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Pegfilgrastim (Injection Route)

Sargramostim (Injection Route)

Lenograstim (Injection Route)

Filgrastim (Injection Route)

Ciclosporin (Oral Route)

Frequently asked questions

Is Bendit 100mg Injection safe?

How does Bendit 100mg Injection work?

Is Bendit 100mg Injection a vesicant?

Does Bendit 100mg Injection cause hair loss/constipation?

Does Bendit 100mg Injection cross blood brain barrier?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Albumin/Globulin Ratio, Serum

Calcium

Complete Blood Count

Kidney Function Test

Peripheral Smear Examination

References

User feedback

What are you using Bendit Injection for?

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

In case of any issues, contact us

Lab tests offered by us

Related/Popular tests