Aclovil 400 Tablet

Reviewed By Dr. Rajeev Sharma, MBA, MBBS

Last updated on 01 Nov 2025 | 04:13 PM (IST)

Aclovil 400 Tablet is an antiviral medicine. It helps in treating viral infections like herpes labialis, herpes simplex, shingles, genital herpes infection, and chickenpox. It prevents the multiplication of virus in human cells and therefore helps in clearing the infection.

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General Information

Contains

Acyclovir (400mg)

Marketer

Fibovil Pharmaceuticals Pvt Ltd

Storage

Store below 25°C

The content is shown in English

Product introduction

Aclovil 400 Tablet should be taken in the dose and duration as advised by your doctor. Do not skip any doses and finish the full course of treatment even if you feel better. Dissolve it in a glass of water before taking it. It may be taken with or without food, but it is better to take it at a fixed time. If you miss a dose, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose. You should drink plenty of water while on treatment with this medicine, as it helps to prevent dehydration and kidney damage.

Some side effects of this medicine include headache, dizziness, vomiting, nausea, fatigue, and fever. Inform your doctor if these side effects do not resolve or persist for a longer duration.

Aclovil 400 Tablet should be used with caution in people with kidney problems, dehydration, or weakened immune systems. It is contraindicated in those allergic to this medicine or similar medicines. Drink plenty of water during treatment to protect kidney function. Please consult your doctor if you are pregnant, planning to conceive, or breastfeeding.

Uses of Aclovil Tablet

Benefits of Aclovil Tablet

Genital herpes infection
Genital herpes is a viral infection that causes painful blisters or sores in the genital area. Aclovil 400 Tablet helps reduce the severity and duration of these outbreaks by controlling the growth of the virus. It also helps relieve pain, itching, and discomfort while promoting faster healing.

Chickenpox
Chickenpox causes itchy blisters, fever, and tiredness, mainly in children. Aclovil 400 Tablet helps control the spread of the virus, reduces the number of blisters, and speeds up recovery. It also lowers the risk of complications, helping the child feel better sooner.

Herpes Simplex Virus Infections
Herpes simplex infections can cause cold sores, blisters, or painful skin lesions. Aclovil 400 Tablet works by stopping the virus from multiplying, helping reduce symptoms like pain and itching. It also shortens healing time and prevents new sores from forming.

Herpes labialis
Herpes labialis, commonly known as cold sores, causes painful blisters around the lips and mouth. Aclovil 400 Tablet helps stop the virus from multiplying, which reduces pain, burning, and itching. It also speeds up healing and helps prevent the formation of new sores.

Shingles
Shingles is a viral infection that causes a painful rash. Aclovil 400 Tablet can shorten the length and severity of shingles. It is most effective if you start taking it as soon as possible after the rash appears. Keeping the immune system healthy is the best way to prevent shingles. Maintaining good hygiene is another way of preventing shingles.

Side effects of Aclovil Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Aclovil

Vomiting
Rash
Nausea
Dry skin
Burning sensation
General discomfort
Itching
Urticaria
Inflammation of vein
Dry lips
Skin peeling

How to use Aclovil Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Aclovil 400 Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Aclovil Tablet works

Aclovil 400 Tablet is an antiviral medication. It prevents the multiplication of virus in human cells. This stops the virus from producing new viruses and clears up your infection.

All substitutes for Aclovil 400 Tablet

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Do not skip any doses and finish the full course of treatment even if you feel better.
Drink plenty of water while on treatment with this medicine. This helps to prevent dehydration and kidney damage.
If you have genital herpes, use barrier methods (condoms) for contraception and avoid sexual contact while the sores are present.
Inform your doctor if you are pregnant or planning to conceive or breastfeeding.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Aclovil 400 Tablet. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Aclovil 400 Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Aclovil 400 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

UNSAFE

Aclovil 400 Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Aclovil 400 Tablet should be used with caution in patients with kidney disease. Dose adjustment of Aclovil 400 Tablet may be needed. Please consult your doctor.
It is advisable to drink plenty of water while you are taking this medicine.

Liver

CAUTION

Aclovil 400 Tablet should be used with caution in patients with liver disease. Dose adjustment of Aclovil 400 Tablet may be needed. Please consult your doctor.

Interaction with drugs

Taking Aclovil with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Severe

Tenofovir disoproxil fumarate (Oral Route)

Do not consume Tenofovir disoproxil fumarate with Acyclovir. If concurrent use is essential, your doctor may monitor your kidney function closely.

Severe

Tacrolimus (Oral Route)

If concurrent use is essential, your doctor may monitor your tacrolimus levels, potassium levels and kidney function closely. They may adjust the doses as per the observations.

Severe

Ciclosporin (Oral Route)

Caution is advised when taking Ciclosporin with Acyclovir. Your doctor may closely monitor the effects of Acyclovir if used concurrently with Ciclosporin and adjust the dose if needed. Acyclovir may raise blood levels of Ciclosporin.

Severe

Ciclosporin (Injection Route)

Moderate

Ceftriaxone (Injection Route)

Talk to your doctor if you notice any unusual symptoms.Doctor may monitor your kidney function.

Frequently asked questions

Will I get cured after taking Aclovil 400 Tablet for shingles?

Aclovil 400 Tablet is an antiviral medicine effective against herpes simplex and varicella zoster viruses. It does not cure infections caused by these viruses but helps to minimize the symptoms and shorten the duration of infection. It does not remove the viruses from the body but prevents the viruses from dividing and spreading.

Does Aclovil 400 Tablet prevent transmission of infection to others?

No, you can infect other people, even while you are being treated with Aclovil 400 Tablet. Herpes infections are contagious, so avoid letting infected areas come into contact with other people. Avoid touching your eyes after touching an infected area. Wash your hands frequently to prevent transmitting the infection to others. You should practice safe sex by using condoms. You should not have sex if you have genital sores or blisters.

What are the serious side effects of Aclovil 400 Tablet?

Serious side effects are rare, but if you experience them, you should seek medical advice right away. These rare side effects include hives, blistering or peeling rash, yellow skin or eyes, unusual bruising or bleeding, loss of consciousness, fits, difficulty in breathing, hallucinations and swelling of the face, tongue, lips or throat.

Do elderly patients need to be more careful while taking Aclovil 400 Tablet?

Older adults (over age 65 years) tend to experience more side effects when taking Aclovil 400 Tablet. The reason being, their kidneys do not flush the drug out of their system as quickly as a younger person’s kidneys would do. Elderly patients should drink plenty of water while taking Aclovil 400 Tablet, and their kidney function should be monitored. These patients should be given a lower dose and should be monitored for neurological problems.

What can happen if somebody takes more than the recommended dose of Aclovil 400 Tablet accidentally?

Accidental, repeated overdoses of oral Aclovil 400 Tablet over several days have resulted in nausea, vomiting, confusion and headache. Consult your doctor in case of overdose.

Can I get resistant to Aclovil 400 Tablet treatment?

Patients with advanced HIV disease or patients with an impaired immunity have reported resistance to Aclovil 400 Tablet. If you are not responding to Aclovil 400 Tablet, the possibility of drug resistance should be checked.

Is hair loss caused due to Aclovil 400 Tablet permanent?

Hair loss is an uncommon side effect of Aclovil 400 Tablet. It stops when the medicine is discontinued.

Will I get cured after taking Aclovil 400 Tablet for shingles?

Does Aclovil 400 Tablet prevent transmission of infection to others?

What are the serious side effects of Aclovil 400 Tablet?

Do elderly patients need to be more careful while taking Aclovil 400 Tablet?

What can happen if somebody takes more than the recommended dose of Aclovil 400 Tablet accidentally?

Accidental, repeated overdoses of oral Aclovil 400 Tablet over several days have resulted in nausea, vomiting, confusion and headache. Consult your doctor in case of overdose.

Can I get resistant to Aclovil 400 Tablet treatment?

Is hair loss caused due to Aclovil 400 Tablet permanent?

Hair loss is an uncommon side effect of Aclovil 400 Tablet. It stops when the medicine is discontinued.

Fact Box

Chemical Class

Nucleoside analog

Habit Forming

Therapeutic Class

ANTI INFECTIVES

Action Class

Antiviral Agents (Non-HIV)

Related lab tests

Herpes Simplex Virus 1 DNA PCR

Herpes Simplex Virus 1 IgG

Herpes Simplex Virus 2 DNA PCR

Herpes Simplex Virus 2 IgG

Herpes Simplex Virus 2 IgM

Varicella Zoster IgG

Varicella Zoster IgM

References

Acosta EP, Flexner C. Antiviral Agents (Nonretroviral). In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. pp. 1594-1600.
Safrin S. Antiviral Agents. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 846-47.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 18-22.
Aciclovir. Hayes, UK: Ranbaxy (UK) Limited a Sun Pharmaceutical Company; 2007 [revised 15 Aug. 2018]. [Accessed 29 Jan. 2019] (online) Available from:
Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-98. [Accessed 29 Mar. 2019] (online) Available from:
Acyclovir [Prescribing Information]. Research Triangle Park, NC: GlaxoSmithKline; 2005. [Accessed 25 Jul. 2024] (online) Available from:
Acyclovir [Prescribing Information]. München, Germany: DENK PHARMA GmbH & Co. KG; 2019. [Accessed 21 Oct. 2025] (online). Available from:

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Fibovil Pharmaceuticals Pvt Ltd
Address: Plot No. 398, Industrial Area, Phase-1, Panchkula 134113

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Aclovil 400 Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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Why we need a prescription?

Provide right medicines

Prescriptions are complex documents. We proof read and recheck at various steps to provide you the right medication in the correct form and dose

In accordance with the law

Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945

Aclovil 400 Tablet

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Aclovil Tablet

Benefits of Aclovil Tablet

Side effects of Aclovil Tablet

How to use Aclovil Tablet

How Aclovil Tablet works

All substitutes for Aclovil 400 Tablet

Acloveer 400 Tablet

Zovirax 400 Tablet

Herperax 400 Tablet

Aciherpin 400mg Tablet

Viromax 400mg Tablet

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Tenofovir disoproxil fumarate (Oral Route)

Tacrolimus (Oral Route)

Ciclosporin (Oral Route)

Ciclosporin (Injection Route)

Ceftriaxone (Injection Route)

Frequently asked questions

Will I get cured after taking Aclovil 400 Tablet for shingles?

Does Aclovil 400 Tablet prevent transmission of infection to others?

What are the serious side effects of Aclovil 400 Tablet?

Do elderly patients need to be more careful while taking Aclovil 400 Tablet?

What can happen if somebody takes more than the recommended dose of Aclovil 400 Tablet accidentally?

Can I get resistant to Aclovil 400 Tablet treatment?

Is hair loss caused due to Aclovil 400 Tablet permanent?

Will I get cured after taking Aclovil 400 Tablet for shingles?

Does Aclovil 400 Tablet prevent transmission of infection to others?

What are the serious side effects of Aclovil 400 Tablet?

Do elderly patients need to be more careful while taking Aclovil 400 Tablet?

What can happen if somebody takes more than the recommended dose of Aclovil 400 Tablet accidentally?

Can I get resistant to Aclovil 400 Tablet treatment?

Is hair loss caused due to Aclovil 400 Tablet permanent?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Herpes Simplex Virus 1 DNA PCR

Herpes Simplex Virus 1 IgG

Herpes Simplex Virus 2 DNA PCR

Herpes Simplex Virus 2 IgG

Herpes Simplex Virus 2 IgM

Varicella Zoster IgG

Varicella Zoster IgM

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

In case of any issues, contact us

Lab tests offered by us

Related/Popular tests