Zosupin 75mg Tablet is a tricyclic antidepressant. It is mostly used to treat depression that is unresponsive to alternative treatment. It is also used in the management of anxiety disorder.
Zosupin 75mg Tablet works by increasing the levels of chemical messengers in the brain that stabilizes and enhances the mood. It is better to take it before bedtime because it can make you feel drowsy. It can be taken with or without food, but you should take it at a fixed time each day for better efficacy. The dose and duration will be decided by your doctor so that you get the right amount to control your symptoms. Do not skip any dose and finish the full course of treatment even if you feel better. This medication must not be stopped suddenly without talking to the doctor. Your dose may be modified or gradually decreased before stopping the medication.
The most common side effects of Zosupin 75mg Tablet include increased heart rate, blurred vision, dryness in the mouth, and constipation. Initially, this medicine may also cause a sudden drop in blood pressure, especially when you change positions. It may even cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. It may also lead to weight gain in some people. Most of the common side effects tend to be mild and temporary. Your doctor may be able to suggest ways of preventing or reducing them. Serious side effects associated with this medicine are rare.
Before taking this medicine, it is important to tell your doctor if you are taking or have recently taken any other medicines for the same or any other diseases. Pregnant and breastfeeding women should take this medicine with proper consultation and caution. This medicine is not known to be addictive, but you can experience additional side effects (withdrawal symptoms) if you stop taking it suddenly. If you notice any sudden mood change or get suicidal or self-harm thoughts, you must consult the doctor without delay. Also, remember to take this medicine strictly as advised by the doctor as an overdose of this medication may lead to a serious health emergency. Consumption of alcohol should strictly be avoided as alcohol interacts with this medicine to cause serious health issues.
Zosupin 75mg Tablet is thought to work by stopping your brain from releasing the chemicals that make you feel anxious so it can reduce the symptoms of excessive anxiety and worry. It can also reduce feelings of restlessness, tiredness, difficulty concentrating, irritability, and sleep problems that often come with Generalised Anxiety Disorder. It will, therefore, help you go about your daily activities more easily and be more productive. Keep taking this medicine even if you feel well. Stopping suddenly can cause serious problems.
Side effects of Zosupin Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Zosupin
Dryness in mouth
Increased heart rate
Orthostatic hypotension (sudden lowering of blood pressure on standing)
Difficulty in urination
Constipation
Blurred vision
How to use Zosupin Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Zosupin 75mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
How Zosupin Tablet works
Zosupin 75mg Tablet is a tricyclic antidepressant. It increases the levels of chemical messengers in the brain that help in regulating the mood and treat depression.
Safety advice
Alcohol
UNSAFE
Zosupin 75mg Tablet may cause excessive drowsiness with alcohol.
Pregnancy
CONSULT YOUR DOCTOR
Zosupin 75mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Zosupin 75mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Zosupin 75mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CONSULT YOUR DOCTOR
There is limited information available on the use of Zosupin 75mg Tablet in patients with kidney disease. Please consult your doctor. However, some studies suggest a cautious use of this medicine in patients with kidney disease.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Zosupin 75mg Tablet in patients with liver disease. Please consult your doctor.
What if you forget to take Zosupin Tablet?
If you miss a dose of Zosupin 75mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
It may take 4 to 6 weeks for Zosupin 75mg Tablet to start working. Keep taking it as prescribed.
It may cause sleepiness. Take it at bedtime and do not drive or do anything requiring concentration until you know how it affects you.
Avoid consuming alcohol when taking Zosupin 75mg Tablet as it may cause excessive sleepiness.
Talk to your doctor if you notice sudden mood changes or develop suicidal thoughts.
Fact Box
Chemical Class
Dibenzoxepin Derivative
Habit Forming
No
Therapeutic Class
NEURO CNS
Action Class
Tricyclic antidepressants
Patient concerns
Mental Depression , Anxiety disorder
Dr. Jyoti Kapoor Madan
Psychiatry
Depression is a persistent state of sadness that is the result of interaction between one's inner biological and psychological state and gets triggered of with environmental stressors. Reactive depression is in response to a situation like loss, sickness, trauma etc. Endogenous depression occurs without any noticeable environmental stressors. Psychological symptoms include lack of interest, negative thinking, irritability, frustration, feeling demotivated etc. Somatic symptoms like fatigue/ weakness/ lack of sleep/ lack of appetite and other physical symptoms are common. Anxiety is common. In severe cases one may feel helpless and hopeless enough to wish for death or attempt suicide. Treatment includes physical and psychiatric work up following which medicines can be prescribed. In milder cases, psychotherapy or counselling is recommended.
Depression is a persistent state of sadness that is the result of interaction between one's inner biological and psychological state and gets triggered of with environmental stressors. Reactive depression is in response to a situation like loss, sickness, trauma etc. Endogenous depression occurs without any noticeable environmental stressors. Psychological symptoms include lack of interest, negative thinking, irritability, frustration, feeling demotivated etc. Somatic symptoms like fatigue/ weakness/ lack of sleep/ lack of appetite and other physical symptoms are common. Anxiety is common. In severe cases one may feel helpless and hopeless enough to wish for death or attempt suicide. Treatment includes physical and psychiatric work up following which medicines can be prescribed. In milder cases, psychotherapy or counselling is recommended.
What are possible physical symptoms of anxiety disorder and depression.
Dr. Subrata Naskar
Psychiatry
Hi PATIENT me clear that for you. Depression is usually associated with a lot of physical symptoms like increased fatigue, decreased amount of sleep or interrupted sleep, loss of appetite usually cause more than 5% body weight loss, loss of libido. But its effect is mainly psychological whivh causes persist low mood, inability to enjoy pleasurable activities, low self esteem, bleak view of the future, guilty feeling etc. These symptoms have to be present persistently for 2 weeks to be called depression. On the other hand, anxiety has two main components, worry and fear. The common physical complaints are extreme sweating, butterfly like feeling in stomach, fidgetiness, increased frequency of urination. If associated with panic attacks, there is often palpitation, respiratory distress, dryness of throat, a sense of doom. Anxiety disorders are of various types and each have varied specific set of symptoms, but these are usually in common.
SUFFERING FROM ACIDITY, SLEEP DISORDER, NAUSIA, DEPRESSION AND ANXIETY AND ALSO FATTY LIVER
Dr. Saurav Arora
Homeopathy
Dear sir your problem can surely be treated with homeopathy but as your case is a chronic case it requires long case taking, examination and regular follow up, therefore, please visit a homeopath so that he can examine you and guide you accordingly. Till the time you can start taking Ipecac 30, 4 drops in half cup water thrice daily. For Do?s and Don?ts while taking homeopathic medicines visit www.arorasclinic.com/homeopathy
I am prescribed Lonazep MD 0.5mg twice a day for anxiety. Its causing me depression. Is there any other GABA medication that is not addictive and does not results in depression?
Dr. Ambrish Dharmadhikari
Psychiatry
Benzodiazepines are usually do not cause depressionSerotonin and norepinephrine reuptake inhibitors are commonly used in anxiety disorderAs well as depression
Anxiety disorder from.past 4 years taking paroxitine and clonazepam 12.5 /0.5 mg
Dr. Jyoti Kapoor Madan
Psychiatry
Based in your clinical history, your doctor plans the type of medicine and it's dose and duration. For first episode of anxiety/ depression/ panic, the usual maintenance phase is 6 months of asymptomatic period, after which medicines can be gradually tapered. But treatment may need to continue longer depending on severity and frequency of episodes. To take any decision to change medication or stop them, several factors have to be taken in account for which regular follow up with your psychiatrist is important. For second opinion, seek a proper consultation with another psychiatrist and take along your previous prescriptions.
Zosupin 75mg Tablet is a medicine used to treat anxiety disorder and depression that is unresponsive to other alternative medicines. It is also used to relieve nerve pain and fibromyalgia. Zosupin 75mg Tablet should be taken only if prescribed by a doctor, exactly as directed.
Q. Is Zosupin 75mg Tablet a muscle relaxant?
No. Zosupin 75mg Tablet is not a muscle relaxant. It is a tricyclic antidepressant (TCA) used in the treatment of depression, nerve pain, and anxiety disorder.
Q. What is the difference between Zosupin 75mg Tablet and amitriptyline?
Zosupin 75mg Tablet is chemically related to Amitriptyline and both are tricyclic antidepressant (TCA) medicine. There is overlap in pharmacological property of this medicine.
Q. Is Zosupin 75mg Tablet the same as doxepin?
Zosupin 75mg Tablet and doxepin are different medicines but belong to the similar chemical class. Doxepin, at low doses, can improve sleep in patients with insomnia. It is also available in the topical form for use in various neuro-dermatitis syndrome, especially itching.
Q. How to stop Zosupin 75mg Tablet?
If your doctor asks you to stop Zosupin 75mg Tablet, you should reduce the dose slowly over 4 weeks. You should not discontinue it abruptly. Sudden discontinuation may cause aggression, anxiety, blurred vision, concentration impairment, constipation and crying spell.
Q. Is Zosupin 75mg Tablet fatal?
Yes. Zosupin 75mg Tablet can be fatal (can cause death) in overdose. This is due to a life-threatening or dangerous side effect in overdose like hyperthermia, seizure, arrhythmia, tachycardia, orthostatic hypotension or sudden death. That's why it is generally not considered a first-line option for depression because of side effect profile.
Q. Can I take Zosupin 75mg Tablet with diazepam?
It is better to avoid this combination. Diazepam is a sedative drug and Zosupin 75mg Tablet may cause sedation as a side effect too. Taking both of them together can increase the drowsiness or sleepiness. Inform your doctor if you are taking diazepam.
Q. Can Zosupin 75mg Tablet be used in the treatment of trigeminal neuralgia?
No. Zosupin 75mg Tablet is not approved for the treatment of trigeminal neuralgia. Trigeminal neuralgia is a chronic pain condition that affects the trigeminal or 5th cranial nerve, one of the most widely distributed nerves in the head.
Q. Can Zosupin 75mg Tablet be used in the treatment of burning mouth syndrome?
No. Zosupin 75mg Tablet is not approved for the treatment of burning mouth syndrome. Burning mouth syndrome is a painful condition of mouth that is burning, scalding, tingling or feeling of numbness that may occur every day for months or longer.
Q. Can I take Zosupin 75mg Tablet for depression?
Yes. Zosupin 75mg Tablet is indicated for the treatment of depression. It has a potential advantage in the patient with depression if associated with insomnia and anxiety. It is generally not considered a first-line option for depression because of side effect profile but very useful for severe or treatment-resistant depression.
Q. Can Zosupin 75mg Tablet used to treat IBS (Irritable Bowel Syndrome)?
No. Zosupin 75mg Tablet is not approved for the treatment of Irritable Bowel Syndrome (IBS). Irritable Bowel Syndrome is a functional gastrointestinal disorder characterised by chronic or recurrent abdominal pain or discomfort associated with altered bowel habits.
Q. Can Zosupin 75mg Tablet be used to treat insomnia with depression?
Yes. Zosupin 75mg Tablet may be used for the treatment of insomnia (too much arousal both at night and during the day) associated with depression. Because it can cause drowsiness or sedation as side effects, it is effective in treating insomnia associated with depression.
Q. Can I use Zosupin 75mg Tablet for fibromyalgia?
Yes. Zosupin 75mg Tablet is not approved for the treatment of fibromyalgia. Fibromyalgia is a pain syndrome with tenderness but no structural pathology in muscles, ligamanets or joints.
Q. Can I use Zosupin 75mg Tablet for nerve pain?
Yes. Zosupin 75mg Tablet is indicated for the treatment of nerve pain/neuropathic pain. Chronic pain/Neuropathic pain is described as pain that arises from damage to, or dysfunction of, any part of peripheral or central nervous system. It is associated with the disease which can affect nerves like diabetes mellitus or herpes infections.
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References
Stahl SM, editor. Dothiepin. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 205-10.
Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 20 Mar. 2019] (online) Available from:
PubChem. Dothiepin. [Accessed 22 Mar. 2019] (online) Available from:
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Dosulepin [Package Insert]. Debrecen, Hungary: TEVA Pharmaceutical Work Private Limited; 2021. [Accessed 25 Jul. 2024] (online) Available from:
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