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Zoladex 3.6 Injection

Goserelin acetate (3.6mg)

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Zoladex 3.6 Injection is used for the treatment of prostate cancer in men and for breast cancer, endometriosis and uterine fibroids in women. In combination with some other medicine, it is used in the treatment of female infertility.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 08 Dec 2025 | 04:23 PM (IST)

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General Information

Contains

Goserelin acetate (3.6mg)

Marketer

AstraZeneca

Storage

Store below 25°C

The content is shown in English

Product introduction

Zoladex 3.6 Injection is given as an injection under the skin by a qualified medical professional.  Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

Hot flashes are a very common side effect of this medicine. It can also cause, decreased libido, and injection site reactions. The long-term use of medicine may cause weakened bones and a reduction in bone mineral density. You are advised to take vitamin D and calcium supplements while taking this medicine. Women might experience vaginal bleeding during the initials days of treatment, which will stop on its own. Consult with your doctor, if this bothers you or does not go away.

Before taking this medicine, inform your doctor if you have a history of drinking alcohol and diabetes. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Uses of Zoladex Injection

Benefits of Zoladex Injection

Female infertility
Zoladex 3.6 Injection may be used in fertility treatments to help prepare the body for assisted reproductive techniques. It helps control hormone levels during specific stages of treatment, improving the chances of successful ovulation and embryo implantation.

Prostate cancer
Zoladex 3.6 Injection is used in men with prostate cancer to slow the growth of cancer cells. It lowers testosterone levels, which helps reduce the size of the tumor and control the spread of the disease, often as part of long-term cancer management.

Breast cancer
Zoladex 3.6 Injection relieves the symptoms of breast cancer such as breast lumps, bloody discharge from nipple or changes in the shape or texture of the breast. It works by altering the production of those hormones in the body that are essential for the growth and spread of breast cancer. It may also interact with other hormones or have a direct effect on cancer to stop its growth.

Endometriosis
Zoladex 3.6 Injection helps reduce the pain and discomfort caused by endometriosis. It works by lowering hormone levels that trigger the growth of endometrial tissue outside the uterus, helping shrink the tissue and relieve symptoms like pelvic pain and painful periods.

Uterine fibroids
Zoladex 3.6 Injection is used to reduce the size of uterine fibroids and relieve related symptoms. It helps control heavy menstrual bleeding, pelvic pressure, and discomfort by shrinking the fibroids before surgery or as part of symptom management.

Side effects of Zoladex Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Zoladex

Hot flushes
Sweating
Decreased appetite
Acne
Breast enlargement
Sexual dysfunction
Erectile dysfunction
Injection site irritation
Decreased libido

How to use Zoladex Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Zoladex Injection works

Zoladex 3.6 Injection is a synthetic hormone. In men, it works by reducing the level of testosterone (male hormone) which causes regression of prostate tumor and improves symptoms. In women, it suppresses the level of estradiol (female hormone) which helps treat advanced breast cancer, endometriosis and uterine fibroids. It also reduces the thickness of the endometrium, which is the uterus lining, prior to surgery.

Quick tips

Zoladex 3.6 Injection is used for the treatment of prostate cancer in men and for breast cancer, endometriosis, and uterine fibroids in women.
It may also be used along with other medicines to treat infertility in women.
It is a prefilled syringe that is injected under the skin of the abdomen, every 28 days.
It may cause a reduction in bone mineral density and weakened bones. Your doctor may prescribe other medicines to reduce bone loss.
Inform your doctor if you start to feel depressed or have disturbing thoughts or feelings during treatment with this medicine.
Vaginal bleeding may occur in the first month after starting treatment and usually stops on its own. Inform your doctor if bleeding continues.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Zoladex 3.6 Injection. Please consult your doctor.

Pregnancy

UNSAFE

Zoladex 3.6 Injection is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.

Breast feeding

CONSULT YOUR DOCTOR

Zoladex 3.6 Injection may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

Driving

SAFE

Zoladex 3.6 Injection does not usually affect your ability to drive.

Kidney

SAFE IF PRESCRIBED

Zoladex 3.6 Injection is safe to use in patients with kidney disease. No dose adjustment is recommended.

Liver

SAFE IF PRESCRIBED

Zoladex 3.6 Injection is safe to use in patients with liver disease. No dose adjustment is recommended.

Interaction with drugs

Taking Zoladex with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Severe

Mizolastine (Oral Route)

Do not consume Mizolastine with Goserelin acetate.

Severe

Amiodarone (Oral Route)

Factors such as old age, chronic heart issues, or low potassium levels may more frequently cause disturbance in heart rhythm, and your doctor may consider ECG monitoring in their presence.

Severe

Amiodarone (Injection Route)

Factors such as old age, chronic heart issues, or low potassium levels may more frequently cause disturbance in heart rhythm, and your doctor may consider ECG monitoring in their presence.

Severe

Artemether (Injection Route)

Factors such as old age, chronic heart issues, or low potassium levels may more frequently cause disturbance in heart rhythm, and your doctor may consider ECG monitoring in their presence.

Severe

Artemether (Oral Route)

Factors such as old age, chronic heart issues, or low potassium levels may more frequently cause disturbance in heart rhythm, and your doctor may consider ECG monitoring in their presence.

Frequently asked questions

What is Zoladex 3.6 Injection used for?

Zoladex 3.6 Injection helps treat certain cancers like prostate and breast cancer by lowering hormone levels, which can make the cancer grow. It is also used for conditions like endometriosis, uterine fibroids, and in fertility treatments to prepare the body for egg collection.

Are there any serious warnings I should know before using Zoladex 3.6 Injection?

Yes, Zoladex 3.6 Injection can affect your mood and may cause depression, sometimes severe. If you feel very sad or notice mood changes, tell your doctor right away. It can also affect your heart rhythm, so your doctor will monitor you if you have heart problems.

Can Zoladex 3.6 Injection cause problems with bones?

Yes, long-term Zoladex 3.6 Injection use may make bones weaker, especially if you already have risk factors for osteoporosis (bone thinning). Your doctor might check your bone health during treatment.

What serious side effects should I watch for after Zoladex 3.6 Injection?

You should watch for signs of serious side effects of Zoladex 3.6 Injection, such as allergic reactions like rash, swelling, trouble breathing, or sudden chest pain. Also, unexpected severe pain in the injection area, signs of bleeding, or sudden weakness should be reported to a doctor immediately.

Can Zoladex 3.6 Injection cause problems with blood sugar or diabetes?

Zoladex 3.6 Injection might raise your blood sugar levels or cause problems if you have diabetes. Your doctor may check your blood sugar and adjust your diabetes treatment if needed.

What should men watch for during treatment with Zoladex 3.6 Injection?

Men should be aware of possible worsening symptoms at the start of Zoladex 3.6 Injection treatment, like bone pain, urinary blockage, or spinal cord pressure. If these occur, immediate medical attention is needed.

Does Zoladex 3.6 Injection affect mood or mental health?

Yes, Zoladex 3.6 Injection can cause mood swings, depression, or memory problems. If you or your family notice changes in your behavior or thinking, talk to your doctor quickly.

Fact Box

Chemical Class

Oligopeptides

Habit Forming

Therapeutic Class

HORMONES

Action Class

Gonadotropin-releasing hormone (GnRH) Agonists

Related lab tests

Anti Mullerian Hormone

Breast Cancer (CA 15.3/ ER/ PR)

Glycosylated Hemoglobin

Prostate Specific Antigen (Free) PSA

Prostate Specific Antigen (Total) PSA

Testosterone Total

Thyroid Stimulating Hormone

References

User feedback

Patients taking Zoladex 3.6 Injection

Once A Month

78%

Once A Day

Once A Week

Twice A Month

Thrice A week

What are you using Zoladex Injection for?

Female infertility

40%

Breast cancer

36%

Prostate cancer

16%

Others

How much was the improvement?

Average

50%

Excellent

31%

Poor

19%

What were the side-effects while using Zoladex 3.6 Injection?

No Side Effect

38%

Decreased libido

25%

Hot flashes

25%

Increased sweating

12%

How do you take Zoladex Injection?

With or without food

56%

With food

44%

Please rate Zoladex 3.6 Injection on price

Expensive

67%

Average

26%

Not Expensive

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: AstraZeneca
Address: Corporate & Registered Office, Block N1, 12th Floor, Manyata Embassy Business Park, Rachenahalli, Outer Ring Road, 560045, Bangalore

Vendor Details

Country of origin: United kingdom
A licensed vendor partner from your nearest location will deliver Zoladex 3.6 Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

Lab tests offered by us

Why we need a prescription?

Zoladex 3.6 Injection

Payment

Return

Expiry after

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Zoladex Injection

Benefits of Zoladex Injection

Side effects of Zoladex Injection

How to use Zoladex Injection

How Zoladex Injection works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Mizolastine (Oral Route)

Amiodarone (Oral Route)

Amiodarone (Injection Route)

Artemether (Injection Route)

Artemether (Oral Route)

Frequently asked questions

What is Zoladex 3.6 Injection used for?

Are there any serious warnings I should know before using Zoladex 3.6 Injection?

Can Zoladex 3.6 Injection cause problems with bones?

What serious side effects should I watch for after Zoladex 3.6 Injection?

Can Zoladex 3.6 Injection cause problems with blood sugar or diabetes?

What should men watch for during treatment with Zoladex 3.6 Injection?

Does Zoladex 3.6 Injection affect mood or mental health?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Anti Mullerian Hormone

Breast Cancer (CA 15.3/ ER/ PR)

Glycosylated Hemoglobin

Prostate Specific Antigen (Free) PSA

Prostate Specific Antigen (Total) PSA

Testosterone Total

Thyroid Stimulating Hormone

References

User feedback

Patients taking Zoladex 3.6 Injection

What are you using Zoladex Injection for?

How much was the improvement?

What were the side-effects while using Zoladex 3.6 Injection?

How do you take Zoladex Injection?

Please rate Zoladex 3.6 Injection on price

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

In case of any issues, contact us

Lab tests offered by us

Related/Popular tests