Zipio 15 Tablet is a medicine used to treat type 2 diabetes mellitus in adults. It helps control blood sugar levels in people with diabetes. This helps to prevent serious complications of diabetes like kidney damage and blindness.

Zipio 15 Tablet may be used by itself or along with other medicines. It may be taken with or without food. Take it regularly at the same time each day to get the most benefit. Your doctor will decide what dose is best for you and this may change from time to time according to how it is working.

Keep taking this medicine, even if you feel well or your blood sugar levels are controlled. If you stop it without consulting your doctor, your blood sugar levels could rise and put you at risk of kidney damage, blindness, nerve problems, and loss of limbs. Remember that it is only part of a treatment program that should also include a healthy diet, regular exercise, and weight reduction as advised by your doctor. Your lifestyle plays a big part in controlling diabetes.

The most common side effects of taking this medicine include headache, sinusitis, muscle pain, and pharyngitis. Consult your doctor if any of these side effects bother you or persist for a longer duration.

You should not take it if you have type 1 diabetes mellitus, if you have diabetic ketoacidosis (high levels of acid in your blood), or if you have severe kidney or liver disease. Before taking this medicine, tell your doctor if you have ever had heart disease, thyroid disease, or some hormonal conditions. It may not be suitable. Pregnant or breastfeeding women should also consult their doctor before taking it. Your blood sugar levels should be checked regularly and your doctor may also advise blood tests to monitor your blood cell counts and liver function.

Uses of Zipio Tablet

Type 2 diabetes mellitus

Side effects of Zipio Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Zipio

Headache
Sore throat
Sinus inflammation
Muscle pain

How to use Zipio Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Zipio 15 Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Zipio Tablet works

Zipio 15 Tablet is an anti-diabetic medication. It works by increasing the body's sensitivity to insulin, a natural substance that helps control blood sugar levels.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Zipio 15 Tablet.

Pregnancy

CONSULT YOUR DOCTOR

Zipio 15 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CAUTION

Zipio 15 Tablet should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.
Monitor the breastfed baby’s blood sugar during treatment with Zipio 15 Tablet

Driving

SAFE

Zipio 15 Tablet does not usually affect your ability to drive.

Kidney

SAFE IF PRESCRIBED

Zipio 15 Tablet is safe to use in patients with kidney disease. No dose adjustment of Zipio 15 Tablet is recommended.

Liver

CAUTION

Zipio 15 Tablet should be used with caution in patients with liver disease. Dose adjustment of Zipio 15 Tablet may be needed. Please consult your doctor.
Use of Zipio 15 Tablet is not recommended in patients with severe liver disease.

What if you forget to take Zipio Tablet?

If you miss a dose of Zipio 15 Tablet, skip it and continue with your normal schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Zipio 15 Tablet

₹1.84/Tablet

Pioz 15 Tablet

USV Ltd

₹7.4/tablet

302% costlier

Pioglit 15 Tablet

Sun Pharmaceutical Industries Ltd

₹7.41/tablet

303% costlier

Piosys 15 Tablet

Systopic Laboratories Pvt Ltd

₹1.8/tablet

2% cheaper

Pioglar 15 Tablet

Sun Pharmaceutical Industries Ltd

₹7.3/tablet

297% costlier

K-Pio 15 Tablet

Blue Cross Laboratories Ltd

₹2.33/tablet

27% costlier

View all substitutes

Quick tips

Zipio 15 Tablet helps to control blood sugar level and avoid long-term complications.
Take it only as per dose and duration suggested by your doctor.
You should continue to exercise regularly, eat a healthy diet, and take your other diabetes medicines along with Zipio 15 Tablet.
Full effects may be visible after several weeks of starting Zipio 15 Tablet. Keep taking it as prescribed by your doctor.
Monitor your blood sugar level regularly while taking this medicine.
Notify your doctor if you experience shortness of breath, heart problems, or any abnormal swelling.
Your doctor may monitor your liver function. Inform your doctor if you notice symptoms like abdominal pain, yellowing of eyes and loss of appetite.
Zipio 15 Tablet helps to control blood sugar level and avoid long-term complications.
Full effects may be visible after several weeks of starting Zipio 15 Tablet. Keep taking it as prescribed by your doctor.
Weight gain, headache, and swelling due to fluid build-up may occur.
Notify your doctor if you experience shortness of breath, heart problems, or any abnormal swelling.
May not be suitable for patients with a history of heart failure or bladder cancer.
You should continue to exercise regularly, eat a healthy diet, and take your other diabetes medicines along with Zipio 15 Tablet.
Take it only as per dose and duration suggested by your doctor.
Monitor your blood sugar level regularly while taking this medicine.
Your doctor may monitor your liver function. Inform your doctor if you notice symptoms like abdominal pain, yellowing of eyes and loss of appetite.

Fact Box

Chemical Class

Thiazolidinedione Derivative

Habit Forming

Therapeutic Class

ANTI DIABETIC

Action Class

Thiazolidinediones (TZD) and PPAR Gamma Agonists

Interaction with drugs

Taking Zipio with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Disopyramide (Oral Route) Severe

Concurrent use may increase the risk of low blood sugar levels. Elderly, malnourished, diabetic individuals and those with kidney and heart dysfunction are at higher risk. If conc... More

Asparaginase (Oral Route) Moderate

Concurrent use may interfere with control over blood sugar. Your doctor may monitor your diabetic control closely and adjust the doses as per the observations.

Aceclofenac (Oral Route) Moderate

Concurrent use may increase the risk of fluid retention and swelling that may cause or worsen heart failure. Do not use Pioglitazone with Aceclofenac. If concurrent use is essenti... More

Aceclofenac (Injection Route) Moderate

Concurrent use may increase the risk of fluid retention and swelling that may cause or worsen heart failure. Do not use Pioglitazone with Aceclofenac. If concurrent use is essenti... More

Clopidogrel (Oral Route) Moderate

Clopidogrel may raise blood levels of Pioglitazone. watch out for symptoms of Pioglitazone side effects such as headache, nausea, dizziness or weakness and consult your doctor if ... More

View all drug interactions

Patient concerns

Diabetes mellitus type 2 ,thirst

Dr. Sanjay Bhatt

Physician

A person can control his or her sugar levels by doing regular exercise and walk or regular aerobic exercises at least 30 to 45 minutes per day.MEDICAL NUTRITIONAL THERAPY THAT IS TO MAINTAIN CALORIES INTAKE AS PER BMI .TAKE HELP OF DIABETIC EDUCATOR. VISIT YOUR DOCTOR AND FOLLOW ALL WHAT DOCTOR SUGGESTED.IN TIME ALL ROUTINE INVESTIGATIONS SHOULD BE DONE.you should not treat it as disease but a start of a healthy life.Uncontrolled sugar levels for long time leads to lower limb weakness which is neuropathy and which is followed by foot ulcers and other complications like kidney or heart problems .online prescription is not allowed without seeing pt.so contact doctor nearby for any change or dose adjustment or visit my clinic at gurgaon sector 52 RdCity snergy multi speciality clinic near SRS MARKET

Diabetes mellitus type 2 required only ayurvedic medicine

Dr. Sanjay Bhatt

Physician

Go for allopathic medicine

Any latest discoveris for type 1 mellitus Diabetes?

Dr. Sanjay Bhatt

Physician

Diabetes Ireland is delighted to hear of the Harvard success and congratulate Professor Melton and colleagues on figuring out the complex series of steps necessary to turn stem cells into beta cells. Hopefully, they can negotiate the regulations for mass production so that an abundant supply of beta cells is available an new and innovative methods will be developed to cure/treat Type 1 diabetes. Type I diabetes is an autoimmune condition whereby the body kills off its own beta (insulin producing) cells resulting in the need for daily insulin administration through the skin. Replacing beta cells in the first step towards a cure, but the replaced beta cells need to be protected from the body?s autoimmune response. This means protecting them in a coating or taking drugs to prevent the response (possible worse side effects than diabetes).

How to manage diabetes mellitus

Dr. Sanjay Bhatt

Physician

A person can control his or her sugar levels by regular exercise and walk or regular aerobic exercises at least 30 to 45 minutes per day.MEDICAL NUTRITIONAL THERAPY THAT IS TO MAINTAIN CALORIES INTAKE AS PER BMI .TAKE HELP OF DIABETIC EDUCATOR. VISIT YOU DOCTOR AND LOW ALL WHAT DOCTOR SUGGESTED.IN TIME ALL ROUTINE INVESTIGATIONS SHOULD BE DONE.you souls not treat it as disease but start of a healthy life.Uncontrolled sugar levels for long time leads to lower limb weakness which is neuropathy and which is followed by foot ulcers and other complications.online prescription is not allowed without seeing pt.so contact doctor nearby for any change or dose adjustment or visit my clinic at gurgaon sector 52 RdCity snergy multi speciality clinic near SRS MARKET

User feedback

Patients taking Zipio 15 Tablet

Once A Day

87%

Thrice A Day

Twice A Day

Alternate Day

What are you using Zipio Tablet for?

Type 2 diabet*

100%

*Type 2 diabetes mellitus

How much was the improvement?

Average

67%

Poor

33%

What were the side-effects while using Zipio 15 Tablet?

No Side Effec*

100%

*No Side Effect

How do you take Zipio Tablet?

With food

100%

Please rate Zipio 15 Tablet on price

Not Expensive

67%

Average

33%

FAQs

Can Zipio 15 Tablet cause weight gain?

Zipio 15 Tablet commonly causes weight gain which may be dose-related. The reason for this weight gain could be fat accumulation. However, in heart failure patients it could be due to water retention in the body. Therefore, it is important to monitor weight in heart failure cases.

Can Zipio 15 Tablet cause heart failure?

Zipio 15 Tablet can cause fluid retention which may aggravate or speed up heart failure. The doctor usually starts with the lowest available dose and increases the dose gradually while treating patients who have at least one risk factor for heart failure (previous heart attack, coronary artery disease, elderly). Heart failure is more common when Zipio 15 Tablet is used with insulin.

Can you take Zipio 15 Tablet and metformin together?

Yes, Zipio 15 Tablet can be used with metformin where sufficient blood sugar management was not possible with metformin alone. This combination of medicines can be used in adult patients with type 2 diabetes mellitus and overweight patients with poor blood sugar control.

What time of day should you take Zipio 15 Tablet?

It is usually prescribed once daily and can be taken at any time of the day but preferably at the same time each day. It can be taken with or without food. You should take Zipio 15 Tablet exactly as prescribed by your doctor.

How long do I need to take Zipio 15 Tablet? Can I stop the medicine for some time?

Continue taking Zipio 15 Tablet as long as your doctor recommends taking it. Treatment for diabetes mellitus is long-term so you may have to take it lifelong. However, if you have to stop it then consult with your doctor who will suggest an alternative. Do not stop taking it without consulting your doctor as it may cause blood sugar levels to rise, which could be harmful to you.

Does Zipio 15 Tablet affect liver?

Yes, Zipio 15 Tablet may cause an increase in liver enzymes, and treatment with Zipio 15 Tablet should be stopped if liver enzymes increase. Hence, levels of liver enzymes should be periodically checked while on treatment with this medicine. Zipio 15 Tablet should not be prescribed to patients with liver disease.

What kind of medicine is Zipio 15 Tablet? Is it like metformin?

Zipio 15 Tablet belongs to the thiazolidinediones class of anti-diabetic medicines. It helps control blood sugar levels by improving how your body uses a hormone called insulin. This is done by helping your cells become more sensitive to the insulin your body makes.

Can Zipio 15 Tablet cause bladder cancer?

Zipio 15 Tablet may increase the risk of bladder cancer, though it is very rare. Immediately consult your doctor if you experience blood in your urine, pain when urinating or a sudden need to urinate, during treatment with this medicine. Zipio 15 Tablet should not be used in patients with a prior history of bladder cancer or having bladder cancer.

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Related lab tests

Glucose - Fasting Blood

Glucose - Postprandial Blood

Glycosylated Hemoglobin

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References

Powers AC, D’Alessio D. Endocrine Pancreas and Pharmacotherapy of Diabetes Mellitus and Hypoglycemia. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1259-61.
Nolte MS. Pancreatic hormones and antidiabetic drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 742-43.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1124-25.
Pioglitazone. Deerfield, Illinois; Takeda Pharmaceuticals America, Inc.; 1999 [revised Nov. 2013]. [Accessed 28 Jan. 2019] (online) Available from:
Pioglitazone hydrochloride [Product monograph]. Ontario, Canada: Takeda Canada Inc.; 2018. [Accessed 8 Oct. 2021] (online) Available from:
Actos [Summary of Product Characteristics]. County Wicklow, Ireland: Takeda Ireland Limited; 2010. [Accessed 8 October. 2021] (online) Available from:
Pioglitazone hydrochloride [Prescribing Information]. Baddi, Himachal Pradesh: Macleods Pharmaceutical Ltd.; 2022. [Accessed 05 Aug. 2023] (online) Available from:
Pioglitazone hydrochloride [Prescribing Information]. Baddi, Himachal Pradesh, India: Macleods Pharmaceutical Ltd.; 2022. [Accessed 05 Aug. 2023] (online) Available from:

Marketer details

Name: FDC Ltd

Address: B-8, MIDC Area, Waluj - 431 136, Dist. Aurangabad, Maharashtra

Country of origin: India

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