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Zaplon 5mg Capsule

Zaleplon (5mg)
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Zaplon 5mg Capsule is used to treat insomnia. It reduces sleep onset time and frequent awakening at night. This medicine improves sleep maintenance and therefore ensures sound sleep.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 29 Apr 2026 | 11:11 AM (IST)
₹30 MRP ₹32.899% off 
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General Information

The content is shown in English
Zaplon 5mg Capsule image
Zaplon 5mg Capsule image

Product introduction

Zaplon 5mg Capsule should be taken on an empty stomach, preferably before going to bed. However, it is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration as advised by your doctor as it is habit-forming. Do not stop taking it suddenly without talking to your doctor as it may worsen your symptoms.

Some common side effects of this medicine include lightheadedness, impaired coordination, and tingling sensation. However, these are temporary and resolve on their own after some time. It also causes dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you and do not take alcohol with it as it may worsen the dizziness. Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, hallucinations, or suicidal thoughts while taking this medicine.

Before taking Zaplon 5mg Capsule, inform your doctor about all other medicines that you are taking, so that your doctor can advise if taking this medicine is right for you. Consult your doctor before taking this medicine if you are suffering from any liver or kidney problems. You should avoid smoking and alcohol while using this medicine. Pregnant and breastfeeding mothers should not use this medicine. However, if the need arises, please consult your doctor before using it.

Uses of Zaplon Capsule

Benefits of Zaplon Capsule

Insomnia
Zaplon 5mg Capsule is used to treat insomnia by helping people fall asleep faster. It supports better sleep onset without causing grogginess the next day, making it useful for those who have trouble falling asleep but not necessarily staying asleep.

Side effects of Zaplon Capsule

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Zaplon
  • Dizziness
  • Lightheadedness
  • Impaired coordination
  • Paresthesia (tingling or pricking sensation)

How to use Zaplon Capsule

Take this medicine in the dose and duration as advised by your doctor. Zaplon 5mg Capsule is to be taken on an empty stomach.

How Zaplon Capsule works

Zaplon 5mg Capsule is a nonbenzodiazepine hypnotic. Along with sedative, it may also have anxiolytic (panic-reducing or antianxiety), muscle relaxant properties. It works by binding GABA-A/chloride ion channel receptor complex (receptor), thus relaxes the nerves and brain. This is how it helps you to fall asleep.

Quick tips

  • Your doctor has prescribed Zaplon 5mg Capsule to help you fall asleep faster and sleep for longer.
  • It is best taken without food as a high-fat meal can reduce its absorption and effect. 
  • Take it 30 to 45 minutes before bedtime and only when you have time to sleep for at least 7 hours.
  • It makes you feel dizzy next morning. Don't drive or do anything requiring concentration until you know how it affects you.
  • It does not affect total sleep time. However,  it reduces sleep onset time and frequent awakening at night.
  • Never share your medication with any other person who also has a sleep problem.
  • Inform your doctor if your sleep doesn’t improve after 7 to 10 days of treatment.
  • Stop taking medication and inform your doctor If you experience sleep driving or memory loss.
  • Do not stop taking medication suddenly as it may lead to anxiety, mood changes, and restlessness. 
  • Your doctor has prescribed Zaplon 5mg Capsule to help you fall asleep faster and sleep for longer.
  • It is best taken without food as a high-fat meal can reduce its absorption and effect. 
  • Take it 30 to 45 minutes before bedtime and only when you have time to sleep for at least 7 hours.
  • It makes you feel dizzy next morning. Don't drive or do anything requiring concentration until you know how it affects you.
  • It does not affect total sleep time. However,  it reduces sleep onset time and frequent awakening at night.
  • Never share your medication with any other person who also has a sleep problem.
  • Inform your doctor if your sleep doesn’t improve after 7 to 10 days of treatment.
  • Stop taking medication and inform your doctor If you experience sleep driving or memory loss.
  • Inform your doctor if you are on depression medication while starting treatment with Zaplon 5mg Capsule. 
  • Do not stop taking medication suddenly as it may lead to anxiety, mood changes, and restlessness. 

Safety advice

Alcohol

Alcohol

UNSAFE
Do not drink alcohol while you are taking this medicine. Zaplon 5mg Capsule may cause excessive drowsiness when taken with alcohol.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Zaplon 5mg Capsule during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Zaplon 5mg Capsule may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Driving

Driving

UNSAFE
Zaplon 5mg Capsule may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

CAUTION
Zaplon 5mg Capsule should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Limited information is available on the use of Zaplon 5mg Capsule in these patients. No dose adjustment is recommended in patients with mild to moderate kidney disease.
Liver

Liver

UNSAFE
Zaplon 5mg Capsule is unsafe to use in patients with liver disease and should be avoided.
Use of Zaplon 5mg Capsule is not recommended in patients with severe liver disease.

Interaction with drugs

Taking Zaplon with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Severe

Tramadol (Injection Route)

If concurrent use is essential, watch out for symptoms of Zaleplon side effects such as drowsiness, excessive sedation, tiredness, dizziness or slurred speech and consult your doctor if you experience them. They may adjust the dose of Zaleplon as per the observations. It is advised to avoid driving or undertaking other tasks requiring skill and alertness.
Severe

Tramadol (Oral Route)

If concurrent use is essential, watch out for symptoms of Zaleplon side effects such as drowsiness, excessive sedation, tiredness, dizziness or slurred speech and consult your doctor if you experience them. They may adjust the dose of Zaleplon as per the observations. It is advised to avoid driving or undertaking other tasks requiring skill and alertness.
Severe

Morphine (Oral Route)

If concurrent use is essential, watch out for symptoms of Zaleplon side effects such as drowsiness, excessive sedation, tiredness, dizziness or slurred speech and consult your doctor if you experience them. They may adjust the dose of Zaleplon as per the observations. It is advised to avoid driving or undertaking other tasks requiring skill and alertness.
Severe

Codeine (Oral Route)

If concurrent use is essential, watch out for symptoms of Zaleplon side effects such as drowsiness, excessive sedation, tiredness, dizziness or slurred speech and consult your doctor if you experience them. They may adjust the dose of Zaleplon as per the observations. It is advised to avoid driving or undertaking other tasks requiring skill and alertness.
Severe

Buprenorphine (Injection Route)

If concurrent use is essential, watch out for symptoms of Zaleplon side effects such as drowsiness, excessive sedation, tiredness, dizziness or slurred speech and consult your doctor if you experience them. They may adjust the dose of Zaleplon as per the observations. It is advised to avoid driving or undertaking other tasks requiring skill and alertness.

Frequently asked questions

Yes, Zaplon 5mg Capsule has abuse potential. However, it is more commonly seen in patients with a history of drug abuse, alcohol consumption, and drug addiction. Therefore, doctors should carefully take history of drug abuse from the patient. Moreover, patients with a history of drug abuse or addiction should be closely monitored during Zaplon 5mg Capsule therapy.
The symptoms of Zaplon 5mg Capsule overdose include drowsiness, confusion, problems with coordination, floppy muscles, slow or difficult breathing, and even coma (loss of consciousness for a period of time).
Zaplon 5mg Capsule can make you drowsy during the daytime and also decrease your mental alertness. Therefore, you should not drive or operate heavy machinery until and unless you know how Zaplon 5mg Capsule affects you. Do not drink alcohol while you are taking Zaplon 5mg Capsule. Alcohol can make the side effects of Zaplon 5mg Capsule even worse.
You should not take Zaplon 5mg Capsule if you are allergic to it or any of its ingredients. You should also avoid Zaplon 5mg Capsule if you have a history of depression, mental illness, or suicidal thoughts. A person having a history of drug or alcohol abuse or addiction, having kidney or liver disease, having a lung disease or breathing problems should avoid Zaplon 5mg Capsule. Also, its consumption is not recommended if you are pregnant, planning to become pregnant, or breastfeeding.
No, do not take Zaplon 5mg Capsule with or shortly after a heavy, high-fat meal. Zaplon 5mg Capsule may not work well if it is taken with high-fat foods.
Zaplon 5mg Capsule is used for short-term (2-4 weeks) treatment of insomnia (difficulty falling asleep). It should be taken exactly as prescribed by the doctor. The dose and duration of treatment should not be exceeded else it may lead to dependence (addiction towards medicine).
Yes, dry mouth is a common side effect of Zaplon 5mg Capsule, whereas weight gain is less common with Zaplon 5mg Capsule. If you experience weight gain, it could be due to increased appetite.
Zaplon 5mg Capsule starts working as soon as you take it and may make you very sleepy. You may remain sleepy for some time after you take the medication. Plan to go to bed right after you take Zaplon 5mg Capsule and to stay in bed for 7 to 8 hours. Do not take Zaplon 5mg Capsule if you will be unable to go to bed right away.
Do not stop taking Zaplon 5mg Capsule without talking to your doctor. If you suddenly stop taking Zaplon 5mg Capsule, you may experience withdrawal symptoms such as unpleasant feelings, stomach and muscle cramps, vomiting, sweating, shakiness, and rarely, seizures.
You can improve your sleep by avoiding caffeine and nicotine, especially late in the day. Avoid exercise during the four hours before bedtime; daily exercise is beneficial to sleep, but can interfere if done close to bedtime. Avoid large meals in the evening. Avoid taking naps. Go to sleep and wake up at the same time each day. Keep the bedroom as dark as possible and maintain a comfortable temperature. Set aside a time to relax before bed and use relaxation techniques.
Insomnia is a common sleep disorder. People with insomnia experience trouble in falling asleep, staying asleep, or both. As a result, they may get too little sleep or have poor-quality sleep, and they may not feel refreshed after waking up.
Insomnia can be of two types- primary or secondary. In primary insomnia, the cause is not known. It can be triggered by life-style changes including long-lasting stress and emotional upset. Whereas, secondary insomnia can be caused due to various reasons such as certain medical conditions (depression, anxiety, post-traumatic stress disorder, Alzheimer's disease, and Parkinson's disease), medicines, sleep disorders, and substances (caffeine and other stimulants, tobacco and other nicotine products, and alcohol).

Fact Box

Chemical Class

Phenylpyrimidines

Habit Forming

Yes

Therapeutic Class

NEURO CNS

Action Class

Non-Benzodiazepine Hypnotics (Z-Drugs)

References

  1. Stahl SM, editor. Zaleplon. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 739-41.
  2. Mihic SJ, Harris RA. Hypnotics and Sedatives. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 467.
  3. Trevor AJ, Way WL. Sedative-Hypnotic Drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 381.
  4. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1503-504.
  5. Zalepon. Sellersville, PA: TEVA PHARMACEUTICALS USA; 2008. [Accessed 19 Mar. 2019] (online) Available from:
  6. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Zaleplon. [Updated 2018 Oct 31]. [Accessed 20 Feb. 2020] (online) Available from:
  7. Central Drugs Standard Control Organisation (CDSCO). [Accessed 19 Mar. 2019] (online) Available from:
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Torrent Pharmaceuticals Ltd
Address: Off. Ashram Road, Ahmedabad - 380 009., Gujarat, India

Vendor Details

Country of origin: India
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