Vincristine GLS 1 Injection
Prescription Required
Product introduction
Vincristine GLS 1 Injection is an anti-cancer medication used in the treatment of breast cancer, non-small cell lung cancer, pancreatic cancer, kidney cancer, blood cancer, multiple myeloma, lymphomas and bone cancer.
Vincristine GLS 1 Injection is given as an injection into the vein under the supervision of a doctor. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
The most common side effects of this medicine include hair loss, peripheral neuropathy (tingling and numbness of feet and hand), and constipation. This medicine may reduce the number of blood cells (white blood cells) in your blood, thereby, increasing the susceptibility to infections and fever. In some cases, it may also cause kidney disease related to uric acid level. Regular blood tests are required to check your blood cells along with heart, liver, and blood uric acid levels.
Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy. you are suggested to avoid direct contact of medicine with eyes, as it may cause eye irritation.
Vincristine GLS 1 Injection is given as an injection into the vein under the supervision of a doctor. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
The most common side effects of this medicine include hair loss, peripheral neuropathy (tingling and numbness of feet and hand), and constipation. This medicine may reduce the number of blood cells (white blood cells) in your blood, thereby, increasing the susceptibility to infections and fever. In some cases, it may also cause kidney disease related to uric acid level. Regular blood tests are required to check your blood cells along with heart, liver, and blood uric acid levels.
Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy. you are suggested to avoid direct contact of medicine with eyes, as it may cause eye irritation.
Uses of Vincristine GLS Injection
Benefits of Vincristine GLS Injection
In Breast cancer
Vincristine GLS 1 Injection helps to treat breast cancer and it may be used alone or in combination with other medicines or treatment modalities like chemotherapy. It relieves the symptoms of breast cancer such as breast lumps, bloody discharge from nipples or changes in the shape or texture of the breast. Vincristine GLS 1 Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. Discuss with your doctor if any of the side effects bother you.
In Non-small cell lung cancer
Non-small cell lung cancer is one of the major kinds of lung cancer and it affects both smokers as well as non-smokers. Vincristine GLS 1 Injection helps treat non-small cell lung cancer and may be given alone or in combination with other medicines. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.
In Pancreatic cancer
Pancreas are very essential for digestion of whatever you eat and also for metabolism of blood sugar levels as they produce the body’s natural insulin. This medicine will help to control pancreatic cancer, and will relieve the symptoms such as, lack of appetite or unexplained weight loss. Vincristine GLS 1 Injection helps to stop the action of those chemicals that aid in pancreatic cancer growth and spread. It will help you live a longer and healthier life.
In Kidney cancer
Vincristine GLS 1 Injection is used to treat kidney cancer and its associated symptoms such as blood in the urine, unexplained low back pain or weight loss, fatigue, loss of appetite, etc. It stops cancer growth and prevents multiplication of cancer cells. This restricts the advancement of cancer to other unaffected regions. You need to follow your doctor’s instructions very carefully to recover.
In Blood cancer
Blood cancer, also called leukemia, is a cancer of the blood-forming tissues, that decreases the body's ability to fight infection. Vincristine GLS 1 Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.
In Multiple myeloma
If you have multiple myeloma, your body is destroying bone faster than it is being replaced. This makes bones weak and painful and more likely to break. Vincristine GLS 1 Injection may be prescribed along with other cancer treatments such as chemotherapy. It is an important part of your treatment and increases the survival rate of people with multiple myeloma. This medicine will kill the cancerous cells and prevent their further growth as well as spread to other parts of the body. Follow your doctor’s instructions carefully to get the most benefit. Supplements of calcium and Vitamin D3 are also effective and may be prescribed if you do not have high blood calcium levels.
In Lymphomas
Lymphomas are certain types of cancer of the infection fighting cells in our body. Vincristine GLS 1 Injection helps to restrict cancer growth and also blocks the action of other chemicals that are required for cancer growth and further spread. Avoid being in crowds and wash your hands often to prevent any infections. Have plenty of fluids, unless otherwise advised by the doctor not to.
In Bone cancer
Bone cancer as the name suggests refers to the cancer of the bones. These are more commonly seen in children and young adults. Vincristine GLS 1 Injection helps to treat bone cancer and it may be used along with other medicines or treatment modalities such as chemotherapy. This medicine kills the cancer cells and also stops the further multiplication and spread of cancer to other unaffected areas. Consult your doctor if any of the side effects bother you.
Side effects of Vincristine GLS Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Vincristine GLS
- Hair loss
- Peripheral neuropathy (tingling and numbness of feet and hand)
- Constipation
How to use Vincristine GLS Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Vincristine GLS Injection works
Vincristine GLS 1 Injection blocks replication of genetic material (DNA) in the cancer cells. Thus it stops the growth and multiplication of cancer cells.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Vincristine GLS 1 Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Vincristine GLS 1 Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
UNSAFE
Vincristine GLS 1 Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
UNSAFE
Vincristine GLS 1 Injection may cause side effects which could affect your ability to drive.
Kidney
CAUTION
Vincristine GLS 1 Injection should be used with caution in patients with kidney disease. Dose adjustment of Vincristine GLS 1 Injection may be needed. Please consult your doctor.
Liver
CAUTION
Vincristine GLS 1 Injection should be used with caution in patients with liver disease. Dose adjustment of Vincristine GLS 1 Injection may be needed. Please consult your doctor.
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Quick tips
- Vincristine GLS 1 Injection is given as a drip in the vein under the supervision of a doctor.
- Do not skip any dose and complete the course as suggested by your doctor.
- Use an effective method of birth control to avoid pregnancy while taking this medication.
- Your doctor may get regular blood tests done to monitor your blood cell count, platelet count and liver function.
- Inform your doctor if you experience skin rash, swelling of face or lips and trouble breathing.
Fact Box
Chemical Class
Vinca alkaloids
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Antimicrotubule agents- Vinka alkaloid
Interaction with drugs
Taking Vincristine GLS with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Concurrent use may cause a decrease in the ability of the bone marrow to produce blood cells.
Do not consume Vincristine from 1 day before until 1 day after taking Sargramostim. P
Concomitant use may cause a reduction in white blood cell levels.
Do not consume Vincristine with Gefitinib.
Do not consume Vincristine with Erlotinib.
Concurrent use may cause a decrease in the ability of the bone marrow to produce blood cells.
Do not consume Vincristine from 14 days before until 24 days after taking Pegfilgrast
Concurrent use may cause a decrease in the ability of the bone marrow to produce blood cells.
Do not consume Lenograstim from 24 hours before until 24 hours after undergoing cytot
Patient concerns
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1706-707.
- Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 949.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1477-79.
- Vincristine sulfate. South San Francisco, California: Talon Therapeutics, Inc.; 2012 [revised Jul. 2012]. [Accessed 27 Mar. 2019] (online) Available from:
- Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Vincristine. [Updated 2020 Jan 20]. [Accessed 19 Feb. 2020] (online) Available from:
Marketer details
Name: GLS Pharma Ltd.
Address: R-4, Khirki Main Road, Malviya Nagar New Delhi- 110 017, (India)
Country of origin: India
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