Vagestone 100mg Injection
Prescription Required
Product introduction
Vagestone 100mg Injection is used to restore menstrual cycles in women whose periods have stopped. It is a natural female hormone important for regulating ovulation (release of an egg from a woman's ovary) and menstruation. It is used in the treatment of infertility to help you get pregnant.
You should use Vagestone 100mg Injection as your doctor has advised. Do not use more or less than you have been advised and do not use it for longer than recommended. You may be asked to continue taking this medicine for a period after it is confirmed that you are pregnant.
The most common side effects include headache, feeling very tired, weight gain, veginal discharge, stomach cramps, pain or swelling in your abdomen and feeling sick. You may also feel bloated, less interested in sex and get pain or discharge in your vagina. Your doctor or nurse may be able to help you reduce or prevent side effects if they bother you or do not go away. Very occasionally people get a severe allergic reaction which needs urgent medical attention. Using this medicine may increase your risk of blood clots or breast cancer.
Vagestone 100mg Injection may not suit everybody, and you should tell your doctor if you have, or have had, breast cancer, unusual bleeding in the vagina or liver disease. You may be monitored more carefully if you have liver, kidney or heart problems or have diabetes or asthma. Let your doctor know your medical history to be safe. Check with your doctor about all other medicines which may affect, or be affected by, this medicine. You will probably have several tests both before and during treatment to check your womb. This medicine can alter your thinking or reactions and you may feel very tired so be careful if you drive or need to be alert. In general, alcohol is not recommended while taking this medicine.
Uses of Vagestone Injection
Benefits of Vagestone Injection
In Female infertility
Vagestone 100mg Injection contains progesterone, a female hormone that is important in the regulation of ovulation and menstruation. It is used to cause menstrual periods in women who have not reached menopause but are not having periods due to a lack of natural progesterone in the body. This medicine helps to prepare the uterus for pregnancy by causing the uterus lining (endometrium) to thicken. This increases the chance of a successful pregnancy. You should use the medicine as prescribed for it to be effective. You may be asked to continue with this treatment for a period after becoming pregnant.
In Hormone replacement therapy
Hormone placement therapy (HRT) is a treatment to relieve symptoms of menopause such as hot flushes, night sweats, mood swings, vaginal dryness, and reduced sex drive. Since menopause can last for several years, this treatment can make a big improvement to your daily life and mood. Progesterone is one of two important hormones (the other being is estrogen) used in this treatment. However it may not treat all your symptoms, consult with your doctor. You should use this medicine as it is prescribed, and for as long as it is prescribed by your doctor.
Side effects of Vagestone Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Vagestone
- Headache
- Fatigue
- Joint pain
- Cough
- Abnormal menstrual bleeding
- Change in body weight
- Musculoskeletal (bone, muscle or joint) pain
- Slurred speech
- Pain behind eyes
- Vertigo
- Vaginal discharge
How to use Vagestone Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Vagestone Injection works
Vagestone 100mg Injection is a progesterone (female hormone). It works on the lining of the uterus and helps to establish and maintain pregnancy in infertile women. It helps in protecting the uterus from the negative effects of oestrogen when used for the treatment of postmenopausal symptoms.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Vagestone 100mg Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Vagestone 100mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Vagestone 100mg Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Vagestone 100mg Injection may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CONSULT YOUR DOCTOR
There is limited information available on the use of Vagestone 100mg Injection in patients with kidney disease. Please consult your doctor.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Vagestone 100mg Injection in patients with liver disease. Please consult your doctor.
Use of Vagestone 100mg Injection is however not recommended in patients with severe liver disease.
Use of Vagestone 100mg Injection is however not recommended in patients with severe liver disease.
What if you forget to take Vagestone Injection?
If you miss a dose of Vagestone 100mg Injection, consult the doctor.
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For informational purposes only. Consult a doctor before taking any medicines.
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Quick tips
- Vagestone 100mg Injection is used in the treatment of female infertility and as a part of hormone replacement therapy.
- It regulates menstrual cycles, treats heavy bleeding, and prevents thickening of the uterus.
- It is also used to restore menstruation in women with secondary amenorrhea (the absence of menstrual cycles).
- It may cause sleepiness or drowsiness. Don't drive or do anything that requires mental focus until you know how Vagestone 100mg Injection affects you.
- It may cause bleeding or spotting in between menstrual periods. Let your doctor know if this occurs frequently.
Fact Box
Chemical Class
Progesterone Derivative
Habit Forming
No
Therapeutic Class
GYNAECOLOGICAL
Action Class
Natural Progesterone
Interaction with drugs
Taking Vagestone with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Progesterone may reduce the efficacy of Fulvestrant.
Do not consume Fulvestrant with Progesterone if you have or had breast cancer. If essential, consult your doctor.
Progesterone may reduce the efficacy of Anastrozole.
Do not consume Anastrozole with Progesterone if you have or had breast cancer. If essential, consult your doctor.
Progesterone is not recommended in individuals with known, suspected, or history of breast cancer. Progesterone may oppose anticancer effects of Tamoxifen.
Do not consume Tamoxife
Progesterone may reduce the efficacy of Letrozole.
Do not consume Letrozole with Progesterone if you have or had breast cancer. If essential, consult your doctor.
If used together, Darunavir may affect blood levels of Progesterone.
It is recommended to use barrier methods (like condoms), IUDs, or a depot for contraception. Your doctor may m
Patient concerns
FAQs
What is Vagestone 100mg Injection?
Vagestone 100mg Injection contains progesterone, which is a natural female sex hormone. It is used to treat menstrual and pregnancy-related issues that are caused due to hormonal imbalance. It may also be prescribed along with estrogen as a part of hormonal replacement therapy for preventing endometrial hyperplasia (thickening of the lining of the uterus).
What is Vagestone 100mg Injection used to treat?
Vagestone 100mg Injection is used to treat various disorders. It is given to women with secondary amenorrhea (no menstruation for 3 months in women who have had their menses before). It is used to support pregnancy, prevent premature labor, and treat bleeding disorders that may occur before menopause. It may be used as a part of fertility treatment and may be given as hormone replacement therapy after menopause. It is also given to relieve symptoms of premenstrual syndrome and painful bleeding like in dysfunctional uterine bleeding.
How and in what dose should I take Vagestone 100mg Injection?
Vagestone 100mg Injection is to be given by a doctor or nurse only. It is given as an injection into the muscle. The dose will depend on the condition you are being treated for and will be decided by your doctor. Follow your doctor’s instructions carefully to get maximum benefit from Vagestone 100mg Injection.
Does Vagestone 100mg Injection cause weight gain?
Yes, the use of Vagestone 100mg Injection may cause weight gain. The reason for this weight gain could be water retention, however this may not be a serious sign. If you are concerned about weight gain, contact your doctor.
How is Vagestone 100mg Injection beneficial for fertility and pregnancy?
Vagestone 100mg Injection consists of progesterone, which is important for fertility. Progesterone is the hormone secreted by the ovaries that helps prepare the uterus for pregnancy and also maintain it. Vagestone 100mg Injection is given in cases of infertility to support the uterus in preparing itself for the pregnancy and to prevent the abortions in some cases. It is also used to prevent premature labor.
Is Vagestone 100mg Injection effective?
Vagestone 100mg Injection is effective if used in the dose and duration advised by your doctor. Do not stop taking it even if you see improvement in your condition. If you stop using Vagestone 100mg Injection too early, the symptoms may return or worsen.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Chrousos GP. The Gonadal Hormones & Inhibitors. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 706-707.
- Levin ER, Hammes SR. Estrogens and Progestins. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1180-85.
- Progesterone. Lodi, Italy: IBSA Farmaceutici Italia Srl; 2013. [Accessed 21 Jun. 2019] (online) Available from:
- Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 03 Apr. 2019] (online) Available from:
- Progesterone [Product Description]. Corona, CA: Watson Laboratories, Inc.; 2007. [Accessed 28 Mar. 2023] (online) Available from:
Marketer details
Name: Bayer Zydus Pharma Pvt Ltd
Address: Bayer House, Central Avenue, Hiranandani Estate, Thane (west) Thane 400607 India
Country of origin: India
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₹66.9
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MRP₹69.71 4% OFF
1.0 Injection in 1 vial
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