Author Details
Written By
MDS, BDS
Reviewed By
MBA, MD Pharmacology
Last updated
10 Dec 2024 | 01:11 AM (IST)

We provide you with authentic, trustworthy and relevant information

Want to know more

Have issue with the content?

Report Problem

Uptofive Tablet

Prescription Required
Storage
Store below 30°C

Product introduction

Uptofive Tablet is a medicine used to treat uterine fibroids (a non-cancerous growth in the uterus) in premenopausal women who cannot undergo surgical treatment or have not responded to surgical intervention.

Uptofive Tablet reduces symptoms like vaginal bleeding, prolonged periods and lower back pain. It can be taken with or without food, but take it at the same time to get the most benefit. It should be taken in the dose and duration prescribed by your doctor. It is important to note that this medicine makes birth control less effective, so use proper contraceptive methods to avoid pregnancy.

This medicine's most common side effects include amenorrhea (absence of menstrual period), headache, dizziness, fatigue, and nausea. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. Usually, your periods stop within 10 days of taking it, but if you still experience heavy bleeding, consult with your doctor. This medicine might stop your period for some time, but periods generally return within 4 weeks after the end of each treatment course.

Before taking this medicine, let your doctor know if you have had liver problems or severe asthma. Your doctor may perform regular blood tests to monitor your liver function while taking Uptofive Tablet. Inform your doctor about all other medications you are taking, as many of these may make this medicine less effective or change how it works. Inform your doctor if you are pregnant or breastfeeding.




Side effects of Uptofive Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Uptofive

  • Absence of menstrual periods
  • Headache
  • Endometrial hyperplasia
  • Fatigue
  • Dizziness
  • Nausea

How to use Uptofive Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Uptofive Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Uptofive Tablet works

Uptofive Tablet is a selective progesterone receptor modulator. It works by modifying the action of progesterone (natural female hormone). It is used either before surgery of fibroids or for intermittent (at regular intervals) treatment of fibroids. It helps reduce their size, stops or controls bleeding and increases your red blood cell count.

Safety advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Uptofive Tablet. Please consult your doctor.
Pregnancy
UNSAFE
Uptofive Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Breast feeding
CONSULT YOUR DOCTOR
Uptofive Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Uptofive Tablet may cause side effects which could affect your ability to drive.
Kidney
CONSULT YOUR DOCTOR
There is limited information available on the use of Uptofive Tablet in patients with kidney disease. Please consult your doctor.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Uptofive Tablet in patients with liver disease. Please consult your doctor.

What if you forget to take Uptofive Tablet?

If you miss a dose of Uptofive Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine

Quick tips

  • Uptofive Tablet is used for the treatment of uterine fibroids and their associated symptoms, such as painful periods, heavy bleeding and pelvic pain.
  • It considerably reduces or stops your menstrual bleeding within the first 10 days of treatment. Notify your doctor if you continue to have heavy bleeding despite taking Uptofive Tablet.
  • Your periods will usually start again within four weeks of stopping Uptofive Tablet.
  • Use a reliable barrier contraceptive method (such as condoms or a diaphragm) to prevent pregnancy while you are taking Uptofive Tablet as it may make hormonal contraceptives (such as pills) less effective.
  • Your doctor may get routine blood tests done to assess the functioning of your liver. Inform your doctor if you notice yellowing of skin/eye, dark urine, or stomach pain.

Fact Box

Chemical Class
Estradiol Derivative
Habit Forming
No
Therapeutic Class
GYNAECOLOGICAL
Action Class
Selective Progesterone Receptor Modulators (SPRMs)

Interaction with drugs

Taking Uptofive with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Carbamazepine may reduce the efficacy of Ulipristal acetate. Do not consume Ulipristal acetate with Carbamazepine. If Ulipristal acetate is essential, ensure a gap of At least 4 w... More
Apalutamide may reduce the efficacy of Ulipristal acetate. Do not consume Ulipristal acetate with Apalutamide. If Ulipristal acetate is essential, ensure a gap of At least 4 weeks... More
Armodafinil may reduce the efficacy of Ulipristal acetate. Do not consume Ulipristal acetate with Armodafinil. If Ulipristal acetate is essential, ensure a gap of At least 4 weeks... More
Bosentan may reduce the efficacy of Ulipristal acetate. Do not consume Ulipristal acetate with Bosentan. If Ulipristal acetate is essential, ensure a gap of At least 4 weeks after... More
Dabrafenib may reduce the efficacy of Ulipristal acetate. Do not consume Ulipristal acetate with Dabrafenib. If Ulipristal acetate is essential, ensure a gap of At least 4 weeks a... More

Patient concerns

arrow
I am suffering with uterine fibroids & get it treated.
Dr. Megha Tuli
Obstetrics and Gynaecology
Treatment would depend on size and site of the fibroids, age and parity and also on symptoms. A detailed evaluation would be required. I suggest you visit a gynaecologist in your area or you could visit me at my clinic in Gurgaon.
How to get treated for uterine fibroids Is fibroid reason for infertility
Dr. Sonu Balhara Ahlawat
Obstetrics and Gynaecology
Maybe it can cause but site of fibroid and the size is important
arrow

FAQs

How does Uptofive Tablet work for fibroids?

Uptofive Tablet acts by blocking the receptors of progesterone, which decreases the levels of progesterone and therefore it is helpful in decreasing the size of fibroids. Fibroids are non-cancerous development around the uterus. When given at a certain prescribed dose, Uptofive Tablet inhibits ovulation leading to stopping of periods. As a result, it may benefit women who have heavy bleeding due to fibroids.

Does Uptofive Tablet stop periods?

No, taking a single tablet of Uptofive Tablet does not stop periods, but it may delay or prepone your periods. In some cases you may have bleeding in between your periods. Consult your doctor if this happens.

Can ulipristal be used as regular birth control medicine?

No, Uptofive Tablet cannot be used as a regular contraceptive. It is meant for occasional use as an emergency contraceptive. It is important to know that the safety and effectiveness of Uptofive Tablet have not been established for repeated use in one menstrual cycle. Hence, its repeated use is not recommended.

How and when should Uptofive Tablet be taken?

Uptofive Tablet should be taken orally as soon as possible after unprotected sex or contraceptive failure and not later than 120 hours (5 days). It can be taken at anytime of the day and before, during or after food. It can be taken at anytime during your menstrual cycle.

What if I vomit after taking Uptofive Tablet?

If you vomit immediately after taking Uptofive Tablet or within 3 hours of taking it, take another tablet of Uptofive Tablet. However, if you have vomited after 3 hours of taking the medicine you need not take another tablet.

Do I need to continue with my regular birth control method?

Uptofive Tablet may make your birth control pills less effective and therefore in addition to birth control pills you should continue using condoms till your next period (menses).

What other important points I need to remember regarding Uptofive Tablet?

While taking Uptofive Tablet you should be aware of some important points such as it does not work if you are already pregnant and it is not effective if you have unprotected sex after taking the tablet. It is also important to know that Uptofive Tablet does not protect against sexually transmitted diseases such as HIV, syphilis etc.

Want to share the information?

Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 1413.
  2. Ulipristal acetate. London: Gedeon Richter (UK) Ltd.; 2012 [revised 26 Jul. 2018]. [Accessed 03 Apr. 2019] (online) Available from:External Link
  3. Ulipristal acetate [Prescribing Information]. Morristown, NJ: Watson Pharma, Inc.; 2010. [Accessed 20 Feb. 2024] (online) Available from: External Link

Marketer details

Name: German Remedies
Address: Zydus Tower, Satellite Cross Roads, Ahmedabad – 380015, Gujarat, India.
Country of origin: India

291
Inclusive of all taxes
MRP300  3% OFF
1.0 Tablet in 1 strip
SOLD OUT
Notify me

INDIA’S LARGEST HEALTHCARE PLATFORM

260m+
Visitors
31m+
Orders Delivered
1800+
Cities
Get the link to download App
Reliable

All products displayed on Tata 1mg are procured from verified and licensed pharmacies. All labs listed on the platform are accredited

Secure

Tata 1mg uses Secure Sockets Layer (SSL) 128-bit encryption and is Payment Card Industry Data Security Standard (PCI DSS) compliant

Affordable

Find affordable medicine substitutes, save up to 50% on health products, up to 80% off on lab tests and free doctor consultations.

LegitScript approved
India's only LegitScript and ISO/ IEC 27001:2022 certified online healthcare platform

Know more about Tata 1mgdownArrow

Access medical and health information

Tata 1mg provides you with medical information which is curated, written and verified by experts, accurate and trustworthy. Our experts create high-quality content about medicines, diseases, lab investigations, Over-The-Counter (OTC) health products, Ayurvedic herbs/ingredients, and alternative remedies.

Order medicines online

Get free medicine home delivery in over 1800 cities across India. You can also order Ayurvedic, Homeopathic and other Over-The-Counter (OTC) health products. Your safety is our top priority. All products displayed on Tata 1mg are procured from verified and licensed pharmacies.

Book lab tests

Book any lab tests and preventive health packages from certified labs and get tested from the comfort of your home. Enjoy free home sample collection, view reports online and consult a doctor online for free.

Consult a doctor online

Got a health query? Consult doctors online from the comfort of your home for free. Chat privately with our registered medical specialists to connect directly with verified doctors. Your privacy is guaranteed.