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    Information about Bosentan

    Bosentan uses

    Bosentan is used in the treatment of pulmonary arterial hypertension (PAH).

    How bosentan works

    Bosentan is an endothelin receptor antagonist. It works by suppressing the action of endothelin, a natural substance that tightens the blood vessels and prevents normal blood flow in patients who have pulmonary hypertension.

    Common side effects of bosentan

    Respiratory tract infection, Anemia (low number of red blood cells)

    Available Medicine for Bosentan

    • ₹760
      Cipla Ltd
      1 variant(s)
    • ₹920
      Lupin Ltd
      1 variant(s)
    • ₹690 to ₹1140
      Sun Pharmaceutical Industries Ltd
      2 variant(s)
    • ₹694 to ₹1900
      Lupin Ltd
      2 variant(s)
    • ₹730
      Natco Pharma Ltd
      1 variant(s)

    Expert advice for Bosentan

    • Your doctor has prescribed Bosentan to treat the high pressure in the blood vessels (the pulmonary arteries) that carry blood from the heart to the lungs.
    • Can help improve your quality of life and exercise ability.
    • Notify your doctor if you are pregnant or planning to conceive or breastfeeding.
    • It is necessary to get routine blood tests done to check for anaemia and to assess the functioning of your liver.

    Frequently asked questions for Bosentan


    Q. What is Bosentan used for/ what is Bosentan therapy?

    Bosentan is used in adults and children to treat high blood pressure in the vessels that carry blood to the lungs (pulmonary arterial hypertension). It is also used in adults for the treatment of painful and difficult to heal open sores on fingers and toes (digital ulcers)

    Q. Does Bosentan work?

    Bosentan is effective if taken at recommended dosage and duration as advised by your doctor

    Q. Is Bosentan an orphan drug?

    Yes, Bosentan is an orphan drug

    Q. Is Bosentan cytotoxic?

    Bosentan is not a cytotoxic drug. However, studies have shown that Bosentan induces liver injury by accumulation of cytotoxic bile salts

    Q. Is Bosentan available in India?

    Yes, it is available in India.

    Content on this page was last updated on 15 January, 2018, by Dr. Varun Gupta (MD Pharmacology)