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Trunap Syrup

Written By Dr. Anuj Saini, MMST, MBBS
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS
Last updated on 30 Mar 2026 | 10:36 AM (IST)
Trunap Syrup is a medicine used in the treatment of insomnia and jet lag (a sleep disorder due to frequent travel to different time zones). It reduces jet lag symptoms such as irritability, indigestion, daytime tiredness, and sleep disturbances.
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General Information

The content is shown in English
Trunap Syrup image
Trunap Syrup image
Trunap Syrup image
Trunap Syrup image

Product introduction

Trunap Syrup helps to synchronize the body’s biological day-night rhythm. It should be taken either 2 hours before or 2 hours after food, preferably at bedtime. However, it is advised to take it at a fixed time each day to maintain a consistent level of medicine in the blood. You should never skip any doses and finish the full course of treatment even if you feel better. This medicine should not be stopped suddenly without talking to your doctor.

Some common side effects of this medicine include headache and drowsiness. It even causes dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. It is important to note that this medicine should not be used for daily naps.

Consult your doctor before taking this medicine if you are suffering from any liver or kidney problems. You should avoid smoking and alcohol while using this medicine. Pregnant and breastfeeding mothers should not use this medicine. However, if the need arises, please consult your doctor before using it.

Uses of Trunap Syrup

Benefits of Trunap Syrup

Treatment of Insomnia
Insomnia is a condition where a person has difficulty falling asleep or staying asleep. Trunap Syrup is often used to support better sleep in individuals facing this issue. It helps regulate the body’s natural sleep-wake cycle, making it easier to fall asleep at night and improving overall sleep quality without causing grogginess the next day.
Treatment of Jet lag
Jet lag occurs when traveling across time zones disrupts the body's internal clock, leading to sleep disturbances and fatigue. Trunap Syrup can help reset this internal clock more quickly by signaling to the body that it is time to sleep, thus reducing the time it takes to adapt to a new schedule and improving alertness during travel.

Side effects of Trunap Syrup

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Trunap
  • Headache
  • Sleepiness

How to use Trunap Syrup

Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. Trunap Syrup is to be taken on an empty stomach.

How Trunap Syrup works

Melatonin is a hormone produced by the body that synchronizes the body’s biological day-and-night rhythm. The biological rhythm can be disturbed by travelling across time zones. This is known as jet lag. The symptoms and their severity vary between individuals, but are generally worse and last longer the more time zones are crossed. Trunap Syrup can help restore the normal day-and-night rhythm and reduce the symptoms.

All substitutes for Trunap Syrup

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

  • Take it with or without food or at least 2 hours before bedtime. 
  • It may affect the blood sugar level. Take caution while taking this medicine if you are suffering from diabetes.
  • It may cause dizziness. Don't drive or do anything requiring concentration until you know how it affects you. 
  • Smoking may make Trunap Syrup less effective since it can increase the metabolism (breakdown) of it by the liver.
  • Avoid alcohol while taking this medicine, as it may decrease the activity of the drug.
  • Inform your doctor if you are taking seizure medicine, as Trunap Syrup may increase the frequency of seizures.
  • Do not take this medicine if you are allergic to Trunap Syrup, suffering from liver or kidney disease, or if you have an intolerance to some sugars.

Safety advice

Alcohol

Alcohol

UNSAFE
It is unsafe to consume alcohol with Trunap Syrup
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Trunap Syrup is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Trunap Syrup may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Driving

Driving

UNSAFE
Trunap Syrup may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

CONSULT YOUR DOCTOR
There is limited data available on the use of Trunap Syrup in patients with kidney disease. Please consult your doctor.
However, based on the limited information available, it is advised that Trunap Syrup should be used with caution in patients with kidney disease.
Liver

Liver

UNSAFE
Trunap Syrup is unsafe to use in patients with liver disease and should be avoided.

Interaction with drugs

Taking Trunap with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Severe

Fluvoxamine (Oral Route)

Do not consume Melatonin with Fluvoxamine. Fluvoxamine may raise blood levels of Melatonin.
Moderate

Thioridazine (Oral Route)

Talk to your doctor if you notice any unusual symptoms.Doctor may monitor your liver function. Melatonin may raise blood levels of Thioridazine.
Moderate

Alprazolam (Oral Route)

Do not drive or do anything requiring concentration or alertness until you know how the medicines affect you.
Moderate

Aripiprazole (Oral Route)

Talk to your doctor if you notice any unusual symptoms.Doctor may monitor your kidney function. Melatonin may decrease the metabolism of Aripiprazole.
Moderate

Pimozide (Oral Route)

Talk to your doctor if you notice any unusual symptoms. Melatonin may raise blood levels of the active form of Pimozide.

Frequently asked questions

The advantages of Trunap Syrup over other sleep agents include that this medicine does not make the patient develop tolerance (after some time of use of Trunap Syrup, it is no longer effective at the same dose). Unlike other similar hypnotic drugs, Trunap Syrup does not cause unwanted effects such as hangovers and physical dependence.
Yes, it may cause weight gain, but it is uncommon. Consult your doctor if you are concerned about putting on weight after taking Trunap Syrup.
Yes, you can take it every night, but consult your doctor for the duration of treatment. If you are taking it for jet lag, you will be advised to take a minimum effective dose for 5 days only. In other cases of insomnia, it can be taken for a little longer, for about 3 months.
Yes, Trunap Syrup may cause an increase in blood pressure, though it is an uncommon side effect. Therefore, if you are hypertensive, keep a watch on your blood pressure during treatment with Trunap Syrup. Consult your doctor as soon as you notice a change in blood pressure.
Usually, Trunap Syrup is taken once a day, before going to bed. Take it exactly as prescribed by your doctor. Trunap Syrup is a natural hormone produced by the body, which peaks at its highest levels at night.
Yes, Trunap Syrup can cause palpitations but only rarely. If you have any concerns regarding palpitations, consult your doctor.
No, unlike other medicines used to help people fall asleep, Trunap Syrup does not cause withdrawal symptoms.
Abnormal dreams are an uncommon side effect of Trunap Syrup. The reason for abnormal dreams is not known, but Trunap Syrup increases the duration of rapid eye movement (REM) sleep. This phase of sleep is usually associated with dreams. This increase in duration of REM could be the reason for abnormal dreams that occur while taking Trunap Syrup.
Yes, Trunap Syrup tablets can be used for treatment of jet-lag in adults. The biological day and night rhythm can be disturbed by travelling to countries lying in different time zones. This is known as jet-lag. The symptoms and their severity vary from person to person, but are generally worse and last longer the more time zones are crossed. Trunap Syrup tablets can help restore the normal day-and-night rhythm and reduce the symptoms.
Early morning awakening is a rare side effect of Trunap Syrup. If this is persistent and is bothering you, consult your doctor.

Fact Box

Chemical Class

3- alkylindoles

Habit Forming

No

Therapeutic Class

NEURO CNS

Action Class

Melatonin Receptor Agonists

References

  1. Dennehy CE, Tsourounis CT. Dietary Supplements & Herbal Medications. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 1123-25.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 857-58.
  3. Melatonin [EMC SmPC]. Barcarena, Portugal: Iberfar - Indústria Farmacêutica S.A; 2018. [Accessed 25 Mar. 2019] (online) Available from:
  4. Melatonin [EMC SmPC]. Dublin 2, Republic of Ireland: Flynn Pharma Ltd.; 2018. [Accessed 25 Mar 2019] (online) Available from:
  5. Central Drugs Standard Control Organisation (CDSCO). [Accessed 25 Mar. 2019] (online) Available from:
  6. Melatonin [Package Leaflet]. London, UK: Colonis Pharma Ltd.; 2021. [Accessed 20 Feb. 2024] (online) Available from:
  7. Melatonin [Summary of Product Characteristics]. Lund, Sweden: AGB-Pharma AB; 2021.
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Manufacturer details

Name: A)Ceego Labs Pvt Ltd
Address: A)S.No:84/1A1,86/3A1, 86/3A2,86/3B1, Manjamedu Village, Thenneri PT - 631 604 Kanchipuram

Marketer details

Name: Shield Health Care Pvt Ltd
Address: No.66, II Cross Street, Pallavan Nagar Extension, Maduravoyal, Chennai 600095, Tamilnadu, India / 15/1, AVN Complex, Vanagaram Service Road, Vanagaram, Maduravoyal, Chennai - 600 095.

Vendor Details

Country of origin: India
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