Tolrina 50mg Tablet

Tofisopam (50mg)

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Tolrina 50mg Tablet belongs to a class of medicines called benzodiazepines. It is used to treat anxiety and depression. It helps relieve anxiety and tension without typically causing significant drowsiness or affecting alertness, memory, or concentration.

Written By Dr. Swati Mishra, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 21 Jul 2026 | 01:02 AM (IST)

₹158 MRP ₹173.629% off

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General Information

Contains

Tofisopam (50mg)

Marketer

Arinna Lifescience Pvt Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Tolrina 50mg Tablet may be taken with or without food. Take it exactly as prescribed by your doctor and try to take it at the same time each day to help you remember your dose. Do not change the dose or stop taking the medicine without consulting your doctor.

The most common side effects include loss of appetite, nausea, constipation, dry mouth, headache, insomnia, and vomiting. These are usually mild and may improve as your body adjusts to the medicine. Consult your doctor if these side effects persist or worsen.

Tell your doctor if you have kidney or liver disease, epilepsy, chronic breathing problems, glaucoma, or any other mental health condition before starting this medicine. Avoid drinking alcohol while taking Tolrina 50mg Tablet, as it may increase the effects of medicines acting on the central nervous system. Also, inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding before taking this medicine.

Uses of Tolrina Tablet

Benefits of Tolrina Tablet

Treatment of Anxiety
Tolrina 50mg Tablet helps relieve anxiety and tension, making you feel calmer and more comfortable in everyday situations. Unlike many other anti-anxiety medicines, it usually does not cause significant drowsiness or affect alertness, memory, or concentration. This allows most people to continue their daily activities with less interference from anxiety symptoms.

Treatment of Depression
Tolrina 50mg Tablet is used to treat depression, especially when it occurs with anxiety. It helps relieve symptoms such as anxiety, tension, fatigue, and apathy, making it easier to carry out daily activities. Regular treatment, as advised by your doctor, may help improve your overall emotional well-being and quality of life.

Side effects of Tolrina Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Tolrina

Constipation
Headache
Loss of appetite
Nausea
Allergic reaction
Insomnia (difficulty in sleeping)
Muscle pain

How to use Tolrina Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Tolrina 50mg Tablet may be taken with or without food.

How Tolrina Tablet works

Tolrina 50mg Tablet helps reduce anxiety by acting on the brain, although its exact way of working is not fully understood. Unlike many other anti-anxiety medicines, it usually does not cause significant drowsiness, muscle relaxation, or affect alertness, memory, or concentration. It helps relieve anxiety and tension while allowing most people to remain mentally alert.

Quick tips

Take Tolrina 50mg Tablet exactly as prescribed by your doctor. Do not change the dose or stop taking it without medical advice.
Tolrina 50mg Tablet usually does not cause significant drowsiness or affect alertness, memory, or concentration. However, avoid driving or operating machinery until you know how it affects you.
Avoid drinking alcohol while taking Tolrina 50mg Tablet, as it may increase the effects of medicines acting on the central nervous system.
Inform your doctor if you have kidney or liver disease, epilepsy, chronic breathing problems, glaucoma, or any other mental health condition before starting treatment.
Tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding before taking this medicine.
The addiction / habit-forming potential of this medicine is very high. Take it only as per the dose and duration advised by your doctor
It may cause dizziness. Do not drive or do anything that requires mental focus until you know how this medicine affects you.
Avoid consuming alcohol as it may increase dizziness and drowsiness.
Inform your doctor if you are pregnant, planning to conceive or breastfeeding.
Do not stop taking medication suddenly without talking to your doctor as that may lead to nausea, anxiety, agitation, flu-like symptoms, sweating, tremor, and confusion.

Safety advice

Alcohol

CAUTION

Alcohol should be used with caution while taking Tolrina 50mg Tablet.

Pregnancy

CONSULT YOUR DOCTOR

Tolrina 50mg Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

UNSAFE

Tolrina 50mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving

SAFE

Tolrina 50mg Tablet does not usually affect your ability to drive.
However, high doses can cause hyperactivity and aggressiveness; therefore, limitations depend on individual patient response.

Kidney

CAUTION

Tolrina 50mg Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.

Liver

CAUTION

Tolrina 50mg Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Tolrina with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Severe

Tramadol (Injection Route)

If concurrent use is essential, watch out for symptoms of Tofisopam side effects such as drowsiness, excessive sedation, tiredness, dizziness or slurred speech and consult your doctor if you experience them. They may adjust the dose of Tofisopam as per the observations. It is advised to avoid driving or undertaking other tasks requiring skill and alertness.

Severe

Clozapine (Oral Route)

If concurrent use is essential, watch out for symptoms such as dizziness, headaches, tremors, sleep disturbances or mood changes and consult your doctor if you experience them. They may adjust the doses as per the observations.

Severe

Tramadol (Oral Route)

Severe

Morphine (Oral Route)

Severe

Codeine (Oral Route)

Frequently asked questions

What is Tolrina 50mg Tablet used for?

Tolrina 50mg Tablet is mainly used to treat anxiety and stress-related symptoms without causing significant sedation. It helps improve mood, mental alertness, and overall daily functioning in people with anxiety disorders.

How does Tolrina 50mg Tablet work for anxiety?

Tolrina 50mg Tablet belongs to a unique class of medicines called benzodiazepines. Unlike traditional benzodiazepines, it reduces anxiety without causing strong drowsiness or affecting mental clarity, making it suitable for daytime use.

Can Tolrina 50mg Tablet cause dependence or withdrawal symptoms?

Tolrina 50mg Tablet has a lower risk of dependence compared to traditional anti-anxiety medicines, but long-term or high-dose use can still lead to dependence. It should only be stopped gradually under a doctor’s supervision.

Who should not take Tolrina 50mg Tablet?

Individuals should not take Tolrina 50mg Tablet if they are allergic to it, have severe liver problems, uncontrolled seizures, or certain rare genetic disorders related to sugar metabolism.

Can Tolrina 50mg Tablet be taken with alcohol?

No, you should avoid alcohol while taking Tolrina 50mg Tablet, as it can increase drowsiness, dizziness, and reduce mental alertness.

Does Tolrina 50mg Tablet interact with other medicines?

Yes, Tolrina 50mg Tablet can interact with medicines such as antipsychotics, antidepressants, anti-seizure medicines, and certain antibiotics. Always inform your doctor about all medicines and supplements you are taking.

Is Tolrina 50mg Tablet safe for elderly patients?

Elderly patients should take Tolrina 50mg Tablet with caution, as they may be more sensitive to its effects, including dizziness and changes in coordination, which can increase the risk of falls.

Can Tolrina 50mg Tablet be used in patients with epilepsy?

Tolrina 50mg Tablet may have some anti-seizure properties, but its use in epilepsy should be carefully monitored by a doctor, especially if combined with other anti-epileptic medicines.

What precautions should people with liver or kidney problems take before using Tolrina 50mg Tablet?

Patients with liver or kidney impairment may need dose adjustments and close monitoring while taking Tolrina 50mg Tablet to avoid side effects.

Can Tolrina 50mg Tablet be used for depression?

Tolrina 50mg Tablet is not an antidepressant, but it may be prescribed alongside antidepressants in patients who have both anxiety and depression to improve overall mood and reduce tension.

Fact Box

Chemical Class

Benzodiazepines

Habit Forming

Yes

Therapeutic Class

NEURO CNS

Action Class

Benzodiazepines

References

User feedback

Patients taking Tolrina 50mg Tablet

Twice A Day

50%

Once A Day

50%

What are you using Tolrina Tablet for?

Depression

100%

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Arinna Lifescience Pvt Ltd
Address: A – 504, Shapath-4, B/S Hotel Crowne Plaza, Opp. Karnavati Club, S. G. Highway ,Ahmedabad 380 051 Gujarat

Vendor Details

Country of origin: India

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Tolrina 50mg Tablet

Tolrina 50mg Tablet

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Tolrina Tablet

Benefits of Tolrina Tablet

Side effects of Tolrina Tablet

How to use Tolrina Tablet

How Tolrina Tablet works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Tramadol (Injection Route)

Clozapine (Oral Route)

Tramadol (Oral Route)

Morphine (Oral Route)

Codeine (Oral Route)

Frequently asked questions

What is Tolrina 50mg Tablet used for?

How does Tolrina 50mg Tablet work for anxiety?

Can Tolrina 50mg Tablet cause dependence or withdrawal symptoms?

Who should not take Tolrina 50mg Tablet?

Can Tolrina 50mg Tablet be taken with alcohol?

Does Tolrina 50mg Tablet interact with other medicines?

Is Tolrina 50mg Tablet safe for elderly patients?

Can Tolrina 50mg Tablet be used in patients with epilepsy?

What precautions should people with liver or kidney problems take before using Tolrina 50mg Tablet?

Can Tolrina 50mg Tablet be used for depression?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

References

User feedback

Patients taking Tolrina 50mg Tablet

What are you using Tolrina Tablet for?

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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