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Tofisern 50mg Tablet

Tofisopam (50mg)
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Tofisern 50mg Tablet belongs to a class of medicines called benzodiazepines. It is used to treat anxiety and depression. It helps relieve anxiety and tension without typically causing significant drowsiness or affecting alertness, memory, or concentration.

Written By Dr. Swati Mishra, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 10 Aug 2026 | 01:04 AM (IST)
₹122 MRP ₹135.9410% off 
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General Information

The content is shown in English
Tofisern 50mg Tablet image
Tofisern 50mg Tablet image

Product introduction

Tofisern 50mg Tablet may be taken with or without food. Take it exactly as prescribed by your doctor and try to take it at the same time each day to help you remember your dose. Do not change the dose or stop taking the medicine without consulting your doctor.


The most common side effects include loss of appetite, nausea, constipation, dry mouth, headache, insomnia, and vomiting. These are usually mild and may improve as your body adjusts to the medicine. Consult your doctor if these side effects persist or worsen.


Tell your doctor if you have kidney or liver disease, epilepsy, chronic breathing problems, glaucoma, or any other mental health condition before starting this medicine. Avoid drinking alcohol while taking Tofisern 50mg Tablet, as it may increase the effects of medicines acting on the central nervous system. Also, inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding before taking this medicine.

Benefits of Tofisern Tablet

Treatment of Anxiety
Tofisern 50mg Tablet helps relieve anxiety and tension, making you feel calmer and more comfortable in everyday situations. Unlike many other anti-anxiety medicines, it usually does not cause significant drowsiness or affect alertness, memory, or concentration. This allows most people to continue their daily activities with less interference from anxiety symptoms.
Treatment of Depression
Tofisern 50mg Tablet is used to treat depression, especially when it occurs with anxiety. It helps relieve symptoms such as anxiety, tension, fatigue, and apathy, making it easier to carry out daily activities. Regular treatment, as advised by your doctor, may help improve your overall emotional well-being and quality of life.

Side effects of Tofisern Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Tofisern
  • Limited data available

How to use Tofisern Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Tofisern 50mg Tablet may be taken with or without food.

How Tofisern Tablet works

Tofisern 50mg Tablet helps reduce anxiety by acting on the brain, although its exact way of working is not fully understood. Unlike many other anti-anxiety medicines, it usually does not cause significant drowsiness, muscle relaxation, or affect alertness, memory, or concentration. It helps relieve anxiety and tension while allowing most people to remain mentally alert.

Quick tips

  • Take Tofisern 50mg Tablet exactly as prescribed by your doctor. Do not change the dose or stop taking it without medical advice.
  • Tofisern 50mg Tablet usually does not cause significant drowsiness or affect alertness, memory, or concentration. However, avoid driving or operating machinery until you know how it affects you.
  • Avoid drinking alcohol while taking Tofisern 50mg Tablet, as it may increase the effects of medicines acting on the central nervous system.
  • Inform your doctor if you have kidney or liver disease, epilepsy, chronic breathing problems, glaucoma, or any other mental health condition before starting treatment.
  • Tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding before taking this medicine.
  • The addiction / habit-forming potential of this medicine is very high. Take it only as per the dose and duration advised by your doctor
  • It may cause dizziness. Do not drive or do anything that requires mental focus until you know how this medicine affects you.
  • Avoid consuming alcohol as it may increase dizziness and drowsiness.
  • Inform your doctor if you are pregnant, planning to conceive or breastfeeding.
  • Do not stop taking medication suddenly without talking to your doctor as that may lead to nausea, anxiety, agitation, flu-like symptoms, sweating, tremor, and confusion.

Safety advice

Alcohol

Alcohol

CAUTION
Alcohol should be used with caution while taking Tofisern 50mg Tablet.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Tofisern 50mg Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.
Breast feeding

Breast feeding

UNSAFE
Tofisern 50mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving

Driving

SAFE
Tofisern 50mg Tablet does not usually affect your ability to drive.
However, high doses can cause hyperactivity and aggressiveness; therefore, limitations depend on individual patient response.
Kidney

Kidney

CAUTION
Tofisern 50mg Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Liver

Liver

CAUTION
Tofisern 50mg Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.
All

Interaction with drugs

Taking Tofisern with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Severe

Tramadol (Injection Route)

If concurrent use is essential, watch out for symptoms of Tofisopam side effects such as drowsiness, excessive sedation, tiredness, dizziness or slurred speech and consult your doctor if you experience them. They may adjust the dose of Tofisopam as per the observations. It is advised to avoid driving or undertaking other tasks requiring skill and alertness.
Severe

Clozapine (Oral Route)

If concurrent use is essential, watch out for symptoms such as dizziness, headaches, tremors, sleep disturbances or mood changes and consult your doctor if you experience them. They may adjust the doses as per the observations.
Severe

Tramadol (Oral Route)

If concurrent use is essential, watch out for symptoms of Tofisopam side effects such as drowsiness, excessive sedation, tiredness, dizziness or slurred speech and consult your doctor if you experience them. They may adjust the dose of Tofisopam as per the observations. It is advised to avoid driving or undertaking other tasks requiring skill and alertness.
Severe

Morphine (Oral Route)

If concurrent use is essential, watch out for symptoms of Tofisopam side effects such as drowsiness, excessive sedation, tiredness, dizziness or slurred speech and consult your doctor if you experience them. They may adjust the dose of Tofisopam as per the observations. It is advised to avoid driving or undertaking other tasks requiring skill and alertness.
Severe

Codeine (Oral Route)

If concurrent use is essential, watch out for symptoms of Tofisopam side effects such as drowsiness, excessive sedation, tiredness, dizziness or slurred speech and consult your doctor if you experience them. They may adjust the dose of Tofisopam as per the observations. It is advised to avoid driving or undertaking other tasks requiring skill and alertness.

Frequently asked questions

Tofisern 50mg Tablet is mainly used to treat anxiety and stress-related symptoms without causing significant sedation. It helps improve mood, mental alertness, and overall daily functioning in people with anxiety disorders.
Tofisern 50mg Tablet belongs to a unique class of medicines called benzodiazepines. Unlike traditional benzodiazepines, it reduces anxiety without causing strong drowsiness or affecting mental clarity, making it suitable for daytime use.
Tofisern 50mg Tablet has a lower risk of dependence compared to traditional anti-anxiety medicines, but long-term or high-dose use can still lead to dependence. It should only be stopped gradually under a doctor’s supervision.
Individuals should not take Tofisern 50mg Tablet if they are allergic to it, have severe liver problems, uncontrolled seizures, or certain rare genetic disorders related to sugar metabolism.
No, you should avoid alcohol while taking Tofisern 50mg Tablet, as it can increase drowsiness, dizziness, and reduce mental alertness.
Yes, Tofisern 50mg Tablet can interact with medicines such as antipsychotics, antidepressants, anti-seizure medicines, and certain antibiotics. Always inform your doctor about all medicines and supplements you are taking.
Elderly patients should take Tofisern 50mg Tablet with caution, as they may be more sensitive to its effects, including dizziness and changes in coordination, which can increase the risk of falls.
Tofisern 50mg Tablet may have some anti-seizure properties, but its use in epilepsy should be carefully monitored by a doctor, especially if combined with other anti-epileptic medicines.
Patients with liver or kidney impairment may need dose adjustments and close monitoring while taking Tofisern 50mg Tablet to avoid side effects.
Tofisern 50mg Tablet is not an antidepressant, but it may be prescribed alongside antidepressants in patients who have both anxiety and depression to improve overall mood and reduce tension.

Fact Box

Chemical Class

Benzodiazepines

Habit Forming

Yes

Therapeutic Class

NEURO CNS

Action Class

Benzodiazepines
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Consern Pharma Limited
Address: 70-71, Ramnik Estate, Village Gonspur, P.O. Nurpur - 141008; H.O.: 308-C, BRS Nagar, Ludhiana, Punjab - 141012, India

Vendor Details

Country of origin: India
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