TIGAtel 12mg Tablet

Tiagabine (12mg)

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TIGAtel 12mg Tablet is an anti-epileptic medicine that is used to treat seizures in adults and children. It may be used alone or in combination with other medicines. It increases the level of a chemical in the brain, which prevents or reduces the number of seizures (epileptic events).

Written By Dr. Lipika Khurana, PGDHHM, BDS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 23 Jan 2026 | 10:15 AM (IST)

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General Information

Contains

Tiagabine (12mg)

Marketer

Sun Pharmaceutical Industries Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

TIGAtel 12mg Tablet must be taken with food, at the same time each day to get the most benefit. The dose will depend on your condition and how you respond to the medicine. Your doctor will advise the right dose for you. You should continue taking it for as long as your doctor has told you to, even if you feel well. If you stop or miss doses your seizures could get worse. It is advised not to change the brand of medication without doctor consultation, and always keep a stock of medicine with you.

The most common side effects of this medicine include impaired concentration, dizziness, low energy, stomach pain, nausea, and nervousness. Some people may also have tremors, altered thinking, drowsiness, and difficulty paying attention. Side effects are more common during the first few weeks and usually lessen as your body gets used to the medicine. Let your doctor know if they persist or bother you. A small number of people being treated with this medicine have had thoughts of harming or killing themselves. Contact your doctor if your mood changes for the worse.

Before taking it, you should tell your doctor if you have kidney problems, depression, or suicidal thoughts and if you are pregnant or planning to become pregnant. You should not breastfeed while taking this medicine. Alcohol may increase the risk of seizures and worsen the side effects such as drowsiness and dizziness. Avoid alcohol while taking this medicine. Drowsiness and dizziness may affect your ability to drive or operate machinery. Your kidney function may need to be tested often while taking this medicine.

Uses of TIGAtel Tablet

Benefits of TIGAtel Tablet

Treatment and prevention of Epilepsy/Seizures
TIGAtel 12mg Tablet slows down electrical signals in the brain which cause seizures (fits). It can also help reduce symptoms such as confusion, uncontrollable jerking movements, loss of awareness, and fear or anxiety. The medicine can allow you to do some activities that you would otherwise be forbidden or scared to do (such as swimming and driving). It can take a few weeks for this medicine to work (because the dose has to be increased slowly) and during this time you may still have seizures. Do not stop using this medicine even if you feel well until your doctor advises you to. Missing doses may trigger a seizure.

Side effects of TIGAtel Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of TIGAtel

Impaired concentration
Dizziness
Low energy
Stomach pain
Nausea
Nervousness
Tremors
Altered thinking
Drowsiness
Difficulty in paying attention

How to use TIGAtel Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. TIGAtel 12mg Tablet should be taken with or after food.

How TIGAtel Tablet works

TIGAtel 12mg Tablet controls seizures by increasing the levels of GABA, a chemical messenger which suppresses the abnormal and excessive activity of the nerve cells in the brain.

Quick tips

It should be taken with food.
Take your medication regularly as directed by your doctor as missing doses can trigger seizures.
Do not change the brand of your medicine and make sure that you have sufficient amount of medicine present with you.
Some healthy tips to prevent seizures:
- Take a healthy diet along with regular exercise.
- Practice yoga every day.
- Get enough sleep at nighttime.
- Limit the use of screen time such as mobile/ laptop.
- Take your medication on time.
Do not drive or do anything that requires mental focus until you know how TIGAtel 12mg Tablet affects you.
Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts or behavior.
Do not stop taking the medication suddenly without talking to your doctor as it may increase the seizure frequency.
You have been prescribed TIGAtel 12mg Tablet for the treatment and prevention of seizures.
Do not change the brand of your medicine and make sure that you have sufficient amount of medicine present with you.
It should be taken with food.
Take your medication regularly as directed by your doctor as missing doses can trigger seizures.
Do not drive or do anything that requires mental focus until you know how TIGAtel 12mg Tablet affects you.
Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts or behavior.
Do not stop taking the medication suddenly without talking to your doctor as it may increase the seizure frequency.
Some healthy tips to prevent seizures:
- Take a healthy diet along with regular exercise.
- Practice yoga every day.
- Get enough sleep at nighttime.
- Limit the use of screen time such as mobile/ laptop.
- Take your medication on time.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with TIGAtel 12mg Tablet. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

TIGAtel 12mg Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of TIGAtel 12mg Tablet during breastfeeding is not available. Please consult your doctor.

Driving

UNSAFE

TIGAtel 12mg Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

SAFE IF PRESCRIBED

TIGAtel 12mg Tablet is safe to use in patients with kidney disease. No dose adjustment is recommended.

Liver

CAUTION

TIGAtel 12mg Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.
Use of TIGAtel 12mg Tablet is not recommended in patients with severe liver disease.

Interaction with drugs

Taking TIGAtel with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Moderate

Sevelamer (Oral Route)

To take Tiagabine, ensure a gap of at least 1 hour before or 3 hours after taking Sevelamer. Your doctor may monitor your treatment and adjust the doses as per the observations.

Moderate

Orlistat (Oral Route)

Watch out for symptoms such as tremors. seizures or impaired coordination and consult your doctor if you experience them. Your doctor may consider separating the administration of Orlistat and Tiagabine. Orlistat may reduce efficacy of Tiagabine.

Moderate

Carbamazepine (Oral Route)

If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations. Carbamazepine may reduce blood levels of Tiagabine.

Moderate

Fosphenytoin (Injection Route)

If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations. Fosphenytoin may reduce blood levels of Tiagabine.

Moderate

Phenobarbitone (Oral Route)

If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations. Phenobarbitone may reduce blood levels of Tiagabine.

Frequently asked questions

Can TIGAtel 12mg Tablet cause addiction?

No, TIGAtel 12mg Tablet is not habit forming. There are no reports of it causing any physical or psychological dependence.

What if I forget to take TIGAtel 12mg Tablet?

Take the missed dose as soon as you remember it. But, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one. If you have missed more than one dose, call your doctor for instructions about re-starting your medication.

How should I take TIGAtel 12mg Tablet when I cross time zones? How should I carry my medicine when I travel? Will I get TIGAtel 12mg Tablet abroad?

It is important to take TIGAtel 12mg Tablet at prescribed interval. Plan ahead and ask your doctor to help you adjust to time zone changes. Carry TIGAtel 12mg Tablet in its original packaging along with doctor’s prescription. TIGAtel 12mg Tablet may be available abroad depending on your destination. But, it is advisable that you carry enough stock for yourself.

How can I watch for early symptoms of suicidal thoughts and actions with TIGAtel 12mg Tablet?

Pay attention to any changes, especially sudden changes in mood, behavior, thoughts or feelings. You should stick to the schedule of all follow-up visits with your doctor. Contact your doctor immediately if your symptoms worsen or bother you.

Can TIGAtel 12mg Tablet have any effect on memory or concentration?

Yes, TIGAtel 12mg Tablet may affect memory and concentration but not in everyone. There may be other factors that may contribute to memory problems like depression, anxiety, sleep disturbance and frequent seizures. Talk to your doctor if you have any of these.

What if I accidentally take more than the recommended dose of TIGAtel 12mg Tablet?

Taking higher than the recommended doses of TIGAtel 12mg Tablet may cause headache, vomiting, shaking, twitching, sleepiness, dizziness, confusion and aggressive behavior. Similarly, it may even make the person silent and withdrawn. High doses of TIGAtel 12mg Tablet may even cause seizures (fits), loss of consciousness, difficulty in breathing or stopped breathing and coma. It is necessary to seek immediate medical attention or go to a nearby hospital.

What if I vomit after taking TIGAtel 12mg Tablet?

If vomiting has occurred within 1 hour of taking TIGAtel 12mg Tablet, then you can repeat the dose. In case you vomit after an hour of taking the medicine, then it must have been absorbed and you need not take another dose. Contact your doctor in case of any queries and worries.

Can phenytoin and TIGAtel 12mg Tablet be taken together?

Phenytoin may interfere with the working of TIGAtel 12mg Tablet. Therefore, the dose of TIGAtel 12mg Tablet may have to be adjusted if both are taken together.

Fact Box

Chemical Class

Piperidinecarboxylic acids

Habit Forming

Therapeutic Class

NEURO CNS

Action Class

GABA Reuptake Inhibitors- Antiepileptic Drugs (AEDs)

References

Stahl SM, editor. Tigabine. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 659-62.
McNamara JO. Pharmacotherapy of the Epilepsies. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 600-601.
Porters RJ, Meldrum BS. Antiseizure Drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 411-12.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 1358.
Tiagabine.North Wales, PA: Teva Pharmaceuticals USA, Inc.; 2015. [Accessed 19 Mar 2019] (online) Available from:
Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Tiagabine. [Updated 2018 Oct 31]. [Accessed 20 Feb. 2020] (online) Available from:
Tiagabine. Harlow, Essex: Cephalon (UK) Limited; 2002 [revised Jul. 2016]. [Accessed 19 Mar. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 22 Mar. 2019] (online) Available from:

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Sun Pharmaceutical Industries Ltd
Address: Khasra No. 1335-1340,Near EPIP- I, Vill - Bhatoli Kalan ,Baddi, Solan, Himachal Pradesh, 173205 || Plot no 107/108,Namli block , Ranipool, East Sikkim 737135

Vendor Details

Country of origin: India

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Why we need a prescription?

TIGAtel 12mg Tablet

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of TIGAtel Tablet

Benefits of TIGAtel Tablet

Side effects of TIGAtel Tablet

How to use TIGAtel Tablet

How TIGAtel Tablet works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Sevelamer (Oral Route)

Orlistat (Oral Route)

Carbamazepine (Oral Route)

Fosphenytoin (Injection Route)

Phenobarbitone (Oral Route)

Frequently asked questions

Can TIGAtel 12mg Tablet cause addiction?

What if I forget to take TIGAtel 12mg Tablet?

How should I take TIGAtel 12mg Tablet when I cross time zones? How should I carry my medicine when I travel? Will I get TIGAtel 12mg Tablet abroad?

How can I watch for early symptoms of suicidal thoughts and actions with TIGAtel 12mg Tablet?

Can TIGAtel 12mg Tablet have any effect on memory or concentration?

What if I accidentally take more than the recommended dose of TIGAtel 12mg Tablet?

What if I vomit after taking TIGAtel 12mg Tablet?

Can phenytoin and TIGAtel 12mg Tablet be taken together?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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