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    Information about Orlistat

    Orlistat uses

    Orlistat is used in obesity. It should be taken along with a low-calorie diet.

    How orlistat works

    Orlistat is a lipase inhibitor. It works in the stomach and small intestine by blocking the absorption of fat from food by blocking enzymes responsible for the breakdown of fat.

    Common side effects of orlistat

    Abdominal pain, Fat in stool , Bowel incontinence, Flatus with discharge, Oily spotting, Diarrhoea, Abdominal cramp, Flatulence, Soft stools

    Available Medicine for Orlistat

    • ₹291 to ₹491
      Meyer Organics Pvt Ltd
      2 variant(s)
    • ₹326 to ₹494
      Lupin Ltd
      2 variant(s)
    • ₹179 to ₹345
      Aristo Pharmaceuticals Pvt Ltd
      2 variant(s)
    • ₹258 to ₹570
      Intas Pharmaceuticals Ltd
      2 variant(s)
    • ₹263 to ₹507
      Torrent Pharmaceuticals Ltd
      2 variant(s)
    • ₹274 to ₹418
      2 variant(s)
    • ₹266 to ₹457
      Eris Life Sciences Pvt Ltd
      2 variant(s)
    • ₹252 to ₹456
      Franco-Indian Pharmaceuticals Pvt Ltd
      2 variant(s)
    • ₹218 to ₹523
      Intas Pharmaceuticals Ltd
      2 variant(s)
    • ₹255 to ₹430
      Sinsan Pharmaceuticals
      2 variant(s)

    Expert advice for Orlistat

    • Safe for long-term use. If taken along with a calorie restricted diet, Orlistat can help decrease nearly 10% of body weight in 1 year.
    • Decreases fat absorption by about 30%.
    • Take during or up to 1 hour after meal.
    • Skip dose if you miss a meal or if your meal contains no fat.
    • A multivitamin supplement containing vitamins A, D, and K, and β-carotene is recommended when taking Orlistat.

    Frequently asked questions for Orlistat


    Q. Is Orlistat available in India?

    Orlistat is available in India with the brand names Orlean, Vyfat, Lipocut, Olistat, Obelit, Orlica, Reeshape, Xenical and Zerofat

    Q. Is Orlistat safe and effective?

    Orlistat is safe and effective if used at prescribed doses for the prescribed duration as advised by your doctor

    Q. Is Orlistat available without prescription?

    Orlistat as Alli is available without prescription but Xenical is available only with prescription. Always consult your doctor regarding its use

    Q. How long can I take Orlistat?

    Therapy should not continue for more than 6 months along with diet and exercise. If the patient does not lose weight in 12 weeks he/she should consult the doctor and follow his advice

    Q. Can I take Orlistat with anti-depressants, antibiotics, gabapentine, levothyroxine, venlafaxine, metformin, raspberry ketones?

    All these drugs are known to have some drug-drug interactions with Orlistat and hence should be taken together only based on doctor's recommendation

    Q. Does Orlistat burn existing fat or reduce appetite?

    Orlistat prevents absorption of fat from the food in the intestine. It does not burn fat. Orlistat may cause reduction of appetite

    Q. Does Orlistat affect the liver or cause cancer?

    No studies of Orlistat affecting the liver or causing cancer have been reported.

    Content on this page was last updated on 15 February, 2018, by Dr. Varun Gupta (MD Pharmacology)