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Orlistat is used in obesity

How it works

Orlistat inhibits enzymes responsible for the breakdown of fats in the intestine. As a result, Orlistat prevents the digestion and absorption of fats in the intestine.

Common side effects

Abdominal pain, Fat in stool , Bowel incontinence, Flatus with discharge, Oily spotting, Diarrhoea, Abdominal cramp, Flatulence, Soft stools

Available Medicine

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  • ₹272 to ₹464
    Meyer Organics Pvt Ltd
    2 variant(s)
  • ₹297 to ₹450
    Lupin Ltd
    2 variant(s)
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    Aristo Pharmaceuticals Pvt Ltd
    2 variant(s)
  • ₹237 to ₹523
    Intas Pharmaceuticals Ltd
    2 variant(s)
  • ₹263 to ₹461
    Torrent Pharmaceuticals Ltd
    2 variant(s)
  • ₹250 to ₹380
    2 variant(s)
  • ₹242 to ₹415
    Eris Life Sciences Pvt Ltd
    2 variant(s)
  • ₹229 to ₹415
    Franco-Indian Pharmaceuticals Pvt Ltd
    2 variant(s)
  • ₹523
    Intas Pharmaceuticals Ltd
    1 variant(s)
  • ₹410
    Sinsan Pharmaceuticals
    1 variant(s)

Expert advice

  • Orlistat should not be taken if patient is allergic to orlistat.
  • It should not be taken by those who have malabsorption (poor absorption) issues.
  • It should not be taken by women who are breast feeding.
  • It should not be taken with a high fat meal.
  • Do not use this drug if you are pregnant.

Frequently asked questions



Is Orlistat available in India?
Orlistat is available in India with the brand names Orlean, Vyfat, Lipocut, Olistat, Obelit, Orlica, Reeshape, Xenical and Zerofat


Is Orlistat safe and effective?
Orlistat is safe and effective if used at prescribed doses for the prescribed duration as advised by your doctor


Is Orlistat available without prescription?
Orlistat as Alli is available without prescription but Xenical is available only with prescription. Always consult your doctor regarding its use

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How long can I take Orlistat?
Therapy should not continue for more than 6 months along with diet and exercise. If the patient does not lose weight in 12 weeks he/she should consult the doctor and follow his advice


Can I take Orlistat with anti-depressants, antibiotics, gabapentine, levothyroxine, venlafaxine, metformin, raspberry ketones?
All these drugs are known to have some drug-drug interactions with Orlistat and hence should be taken together only based on doctor's recommendation


Does Orlistat burn existing fat or reduce appetite?
Orlistat prevents absorption of fat from the food in the intestine. It does not burn fat. Orlistat may cause reduction of appetite


Does Orlistat affect the liver or cause cancer?
No studies of Orlistat affecting the liver or causing cancer have been reported.

Content on this page was last updated on 22 February, 2017, by Dr. Varun Gupta (MD Pharmacology)