Thiepin 25mg Tablet

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Primarily used for

Depression, Neuropathic pain (Pain due to damage of nerves), Anxiety disorder
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Medicine Overview of Thiepin Tablet

uses

Uses of Thiepin Tablet

Thiepin 25mg Tablet is used in the treatment of depression, neuropathic pain and anxiety disorder.
It is used in patients intolerant of or unresponsive to alternative treatment options for depression.
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Side effects of Thiepin Tablet

Common

Dry mouth, Blurred vision, Sleepiness, Increased heart rate, Orthostatic hypotension (sudden lowering of blood pressure on standing), Weight gain, Difficulty in urination, Constipation.

uses

How to use Thiepin Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. It can be taken with or without food, but it is better to take Thiepin 25mg Tablet at a fixed time.

How Thiepin Tablet works

Thiepin 25mg tablet increases the levels of chemical messengers in the brain that help in regulating the mood and treat depression.

In Depth Information on Thiepin Tablet

Expert advice for Thiepin Tablet

  • The main dose should be taken at night as this drug may produce drowsiness or sleepiness.
  • It can take 4 to 6 weeks for Thiepin to start working.
  • You should continue the treatment for at least 6 months after you feel better to stop depression from coming back.
  • If your doctor asks you to stop Thiepin, you should reduce the dose slowly over 4 weeks. You should not discontinue it abruptly.
  • Avoid driving or operating machinery as it may decrease alertness.
  • Avoid consuming alcohol when taking the Thiepin, as it may cause excessive drowsiness and calmness.
  • The addiction/dependence potential of Thiepin is very less.
  • It may be extremely dangerous in overdose.
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Warnings
Special precautions for Thiepin 25mg Tablet
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Alcohol
Interaction with alcohol is unknown. Please consult your doctor.
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Pregnancy
WEIGH RISKS VS BENEFITS
Thiepin 25mg Tablet may be unsafe to use during pregnancy.

Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
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Lactation
CAUTION
Thiepin 25mg Tablet is probably usafe to use during lactatio
n. Limited human data suggests that the drug could represent a significant risk to the baby.
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Driving
It is not known whether Thiepin 25mg Tablet alters the abili
ty to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
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Kidney
There is limited information available on the use of Thiepin 25mg Tablet in patients with kidney disease. Please consult your doctor.

However, some studies suggest a cautious use of this medicine in patients with kidney disease.
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Liver
There is limited information available on the use of Thiepin
25mg Tablet in patients with liver disease. Please consult your doctor.
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Severely interacts with other drugs like
Linowin 200mg Injection, Mezolam 7.5mg Injection, Tramazac HP 50mg Injection, Medzol 1mg Injection

Missed Dosageuses

If you miss a dose of Dosulepin / Dothiepin, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Patient Concerns

Frequently asked questions for Thiepin 25mg Tablet

Frequently asked questions for Dosulepin / Dothiepin

No. Thiepin is an antidepressant (TCA) that is used to treat depression, nerve pain, and anxiety disorder. It can cause drowsiness or sedation as a side effect. Therefore caution is advised when driving or operating dangerous machinery and even when getting out of bed at night.
No. Thiepin is not a muscle relaxant. It is a tricyclic antidepressant (TCA) used in the treatment of depression, nerve pain, and anxiety disorder.
Q. What is the difference between Thiepin and amitriptyline?
Thiepin is chemically related to Amitriptyline and both are tricyclic antidepressant (TCA) medicine. There is overlap in pharmacological property of this medicine.
Q. Is Thiepin the same as doxepin?
Thiepin and doxepin are different medicines but belong to the similar chemical class. Doxepin, at low doses, can improve sleep in patients with insomnia. It is also available in the topical form for use in various neuro-dermatitis syndrome, especially itching.
If your doctor asks you to stop Thiepin, you should reduce the dose slowly over 4 weeks. You should not discontinue it abruptly. Sudden discontinuation may cause aggression, anxiety, blurred vision, concentration impairment, constipation and crying spell.
Yes. Thiepin can be fatal (can cause death) in overdose. This is due to a life-threatening or dangerous side effect in overdose like hyperthermia, seizure, arrhythmia, tachycardia, orthostatic hypotension or sudden death. That's why it is generally not considered a first-line option for depression because of side effect profile.
Q. Can Thiepin be used along with mirtazapine?
It is better to avoid Thiepin with mirtazapine. Mirtazapine, which is used in the treatment of depression, can potentiate the sedative effects of Thiepin.
Q. Can Thiepin be used with citalopram?
No. Citalopram and Thiepin both are the antidepressant. Citalopram may increase the high blood level of Thiepin. This may lead to a life-threatening or dangerous side effect of hyperthermia, seizure, arrhythmia, tachycardia, orthostatic hypotension or sudden death.
Q. Can Thiepin be used with sertraline?
No. Sertraline and Thiepin both are the anti-depressant. Sertraline may increase the high blood level of Thiepin. This may lead to a life-threatening or dangerous side effect of hyperthermia, seizure, arrhythmia, tachycardia, orthostatic hypotension or sudden death.
Q. Can I take Thiepin with diazepam?
It is better to avoid this combination. Diazepam is a sedative drug and Thiepin may cause sedation as a side effect too. Taking both of them together can increase the drowsiness or sleepiness. Inform your doctor if you are taking diazepam.
No. Thiepin is not approved for the treatment of trigeminal neuralgia. Trigeminal neuralgia is a chronic pain condition that affects the trigeminal or 5th cranial nerve, one of the most widely distributed nerves in the head.
No. Thiepin is not approved for the treatment of burning mouth syndrome. Burning mouth syndrome is a painful condition of mouth that is burning, scalding, tingling or feeling of numbness that may occur every day for months or longer.
Yes. Thiepin is indicated for the treatment of depression. It has a potential advantage in the patient with depression if associated with insomnia and anxiety. It is generally not considered a first-line option for depression because of side effect profile but very useful for severe or treatment-resistant depression.
No. Thiepin is not approved for the treatment of Irritable Bowel Syndrome (IBS). Irritable Bowel Syndrome is a functional gastrointestinal disorder characterised by chronic or recurrent abdominal pain or discomfort associated with altered bowel habits.
Yes. Thiepin may be used for the treatment of insomnia (too much arousal both at night and during the day) associated with depression. Because it can cause drowsiness or sedation as side effects, it is effective in treating insomnia associated with depression.
Yes. Thiepin is not approved for the treatment of fibromyalgia. Fibromyalgia is a pain syndrome with tenderness but no structural pathology in muscles, ligamanets or joints.
Yes. Thiepin is indicated for the treatment of nerve pain/neuropathic pain. Chronic pain/Neuropathic pain is described as pain that arises from damage to, or dysfunction of, any part of peripheral or central nervous system. It is associated with the disease which can affect nerves like diabetes mellitus or herpes infections.
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