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MD Pharmacology, MBBS
Last updated
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Systroin 10 Capsule

Prescription Required
Manufacturer/ Marketer
SALT COMPOSITION
Storage
Store below 30°C
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Product introduction

Systroin 10 Capsule belongs to a group of medicines called retinoids (vitamin A derivative). It is used to treat severe acne that has not responded to other treatments.

Systroin 10 Capsule should be used in the dose and duration as advised by your doctor. Take it with food, preferably at the same time each day to avoid a missed dose. It may take several weeks for your symptoms to improve but keep taking the medicine regularly to get the most benefit. If you notice no improvement after a few weeks, see your doctor again.

The most common side effects include dry skin, rash, and increased liver enzymes. They are not usually serious and often disappear after getting used to the medicine but if they bother you or do not go away, tell your doctor.

Systroin 10 Capsule may make you more sensitive to sunlight so you should limit your exposure to the sun. It may also make your skin more fragile. Avoid any waxing (hair removal), or laser treatments during treatment. Additionally, it may cause dryness of the mouth, lips, and eyes so drink plenty of water and use a moisturizer. This medicine may lead to birth defects, do consult your doctor if you are pregnant or planning pregnancy.

Uses of Systroin Capsule

Benefits of Systroin Capsule

In Treatment of Acne

Systroin 10 Capsule helps treat acne by reducing the production of sebum (a natural substance) that causes acne. This kills acne-causing bacteria and prevents spots or pimples from appearing. It usually takes a few weeks to have a noticeable effect so keep taking it even if it appears not to be working. Sometimes acne may get worse before it gets better, however, with proper use, your skin will get clearer. This medicine will help improve your mood and uplift your confidence as your skin becomes acne-free.

Side effects of Systroin Capsule

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Systroin

  • Dry skin
  • Increased liver enzymes
  • Rash

How to use Systroin Capsule

Take this medicine in the dose and duration as advised by your doctor. Systroin 10 Capsule is to be taken with food.

How Systroin Capsule works

Systroin 10 Capsule is a derivative of vitamin A. It acts on glands (sebaceous) to reduce the production of a natural substance (sebum) that causes acne. Also, the controlled sebum production kills acne-causing bacteria. It also works as an anti-inflammatory to decrease inflammation (redness and swelling).

Safety advice

Alcohol
CAUTION
Caution is advised when consuming alcohol with Systroin 10 Capsule. Please consult your doctor.
Pregnancy
UNSAFE
Systroin 10 Capsule is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Breast feeding
CONSULT YOUR DOCTOR
Systroin 10 Capsule is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Systroin 10 Capsule may cause side effects which could affect your ability to drive.
Your night vision may get worse during your treatment. This can happen suddenly. Drowsiness and dizziness have been reported very rarely. This may affect your driving ability.
Kidney
SAFE IF PRESCRIBED
Systroin 10 Capsule is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Systroin 10 Capsule may not be needed in these patients. Please consult your doctor.
If you experience excessive tiredness, puffy eyes and difficulty in urination while taking this medicine, inform your doctor and stop the therapy.
Liver
UNSAFE
Systroin 10 Capsule is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.

What if you forget to take Systroin Capsule?

If you miss a dose of Systroin 10 Capsule, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Systroin 10 Capsule
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Cutitret 10mg Capsule
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Sebostop 10 Capsule
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Resoten 10 Capsule
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Isoace 10mg Capsule
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Quick tips

  • You have been prescribed Systroin 10 Capsule for the treatment of severe acne.
  • Take it with food.
  • Avoid exposure to sunlight while using Systroin 10 Capsule. Use protective measures such as sun-cream or protective clothing.
  • Avoid face waxing and laser treatment while using this medicine as it makes your skin more fragile.
  • It may cause dryness of mouth, lips, and eyes. Drink plenty of water, use moisturiser and avoid wearing contact lenses. Inform your doctor if it bothers you.
  • Do not take Systroin 10 Capsule if you are pregnant, planning pregnancy or breastfeeding.

Fact Box

Chemical Class
Retinoid
Habit Forming
No
Therapeutic Class
DERMA
Action Class
Retinoids- First generation

Patient concerns

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Hi, 3 months back I was diagnosed with PCOD and Hypothyroidsm. My doctor has prescribed Okamet, Acenchio and Systroin for PCOD ( I have acne problem and eltrxin 50 mg for hypothroidsm. I have been asked to apply clindamycin, benzoyl peroxide and a de pigmentation cream for my acne and its marks. I am also using a prescribed facewash and sunprotect sunscreen. The results are good. However, I still get a pimple or two before my periods. I have been told it will happen. I also get pains in pelvic region due to pcod, I know there is no cure for this but I wish something could be done about this. Isnt there any way to get rid of acne as whole. I have a healthy diet, I drink ample water, eat 2 fruits a day, walk a lot and eat junk food once a month. But, I dont know why I am not satisfied. Where am I going wrong? PS: My marks are clearing but I've stopped using the cream. I apply fresh aloe vera on my scars overnight.
Dr. Sonu Balhara Ahlawat
Obstetrics and Gynaecology
Kindly go to the same doctor again
Please suggest better treatment for acne and piles
Dr. Atul Jain
Dermatology
For acne-use Nadoxin gel at night over acne For piles-pls visit near general surgeon
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User feedback


FAQs

Q. Is Systroin 10 Capsule safe to use?

Systroin 10 Capsule should be used with care since it is associated with significant adverse reactions. It should be used only for patients with severe nodular acne who are unresponsive to conventional therapy, including systemic antibiotics. In addition, Systroin 10 Capsule should not be used by pregnant women because it can cause severe birth defects.

Q. Is Systroin 10 Capsule a steroid?

No, Systroin 10 Capsule is a retinoid (vitamin A) which is used to treat severe types of acne.

Q. What are the recommended tests during Systroin 10 Capsule therapy?

Your liver enzymes and serum lipids will be checked before the treatment is started. These levels will also be monitored 1 month after the start of treatment and subsequently at 3 monthly intervals unless more frequent monitoring is clinically indicated.

Q. Is the effect of Systroin 10 Capsule permanent?

It has been observed in many patients that a single 15-20-week course effectively cures the condition and prevents it from coming back. If at all a second course is required, one should wait for at least 8 weeks after completion of the first course. This is because experience with Systroin 10 Capsule has shown that the symptoms in the patients with acne may continue to improve following treatment with Systroin 10 Capsule.

Q. Why is Systroin 10 Capsule so dangerous during pregnancy?

If pregnancy occurs during treatment with Systroin 10 Capsule then, there is an extremely high risk that the baby may be born with severe birth defects.

Q. Can Systroin 10 Capsule cause cancer?

No, there are no reports of Systroin 10 Capsule causing cancer. In fact, it may be useful in some forms of head, skin, and neck cancers.

Q. What are the long-term side effects of Systroin 10 Capsule?

A normal course of treatment of Systroin 10 Capsule is 15–20 weeks. Therefore, the long-term effects of low doses have not been studied. However, it may have some effect on bone mineral density. It may decrease bone mineral density in some patients, resulting in osteoporosis or fractures.

Q. Does Systroin 10 Capsule affect male fertility?

No, Systroin 10 Capsule does not affect the fertility of male patients. No significant effects were seen on ejaculate volume, sperm count, total sperm motility, morphology, or seminal plasma fructose.

Q. Does Systroin 10 Capsule damage your liver?

There may be a transient increase in liver enzymes with Systroin 10 Capsule use. Therefore, regular laboratory tests are required. These values generally return to normal after some time. If the levels remain elevated for a long time, your doctor may discontinue the use of Systroin 10 Capsule.

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Robertson DB, Maibach HI. Dermatologic Pharmacology. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 1056.
  2. Burkhart C, Morrell D, Goldsmith L. Dermatological Pharmacology. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1812.
  3. Sardana K, Madan A. How to Treat Acne. Sardana K, editor. In: Clinical Approach to Acne Vulgaris. 1st ed. New Delhi: CBS Publishers & Distributors Pvt. Ltd.; 2015. pp. 64-67.
  4. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 745-47.
  5. Isotretinoin. Hayes, UK; Ranbaxy (UK) Limited a Sun Pharmaceutical Company; 2006 [revised 17 Nov. 2017]. [Accessed 23 Jan. 2019] (online) Available from:External Link
  6. Isotretinoin. Nutley, New Jersey: Roche Laboratories Inc.; 2002. [Accessed on 2 Apr. 2019] (online) Available from:External Link
  7. Central Drugs Standard Control Organisation (CDSCO). [Accessed 03 Apr. 2019] (online) Available from:External Link

Manufacturer/Marketer address

104, sarja market, Naharpur, sector 7, Rohini, Delhi - 110085, Near pnb bank (Map)
Country of origin: India
Expires on or after: September, 2023

A licensed vendor partner from your nearest location will deliver Systroin 10 Capsule. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
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