Srgest 300mg Capsule

Reviewed By Dr. Rajeev Sharma, MBA, MBBS

Last updated on 15 Dec 2025 | 05:54 PM (IST)

Srgest 300mg Capsule provides progesterone, which is a natural hormone essential for reproductive health. It is used to support pregnancy in female infertility and as part of hormone replacement therapy. It helps regulate the menstrual cycle, prepares the uterus for pregnancy, and balances hormones.

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General Information

Contains

Progesterone (300mg)

Marketer

Ordain Health Care Global Pvt Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

You should use Srgest 300mg Capsule as your doctor has advised. Do not use more or less than you have been advised, and do not use it for longer than recommended. You may be asked to continue taking this medicine for a certain period after it is confirmed that you are pregnant.

The most common side effects include headache, stomach cramps, irregular vaginal bleeding or spotting, fluid retention, and nausea. Your doctor may be able to help you reduce or prevent side effects if they bother you or do not go away. Very occasionally, people get a severe allergic reaction that needs urgent medical attention.

Using this medicine may increase your risk of blood clots or breast cancer. Srgest 300mg Capsule may not suit everybody, and you should tell your doctor if you have, or have had, breast cancer, unusual bleeding in the vagina, or liver disease. You may be monitored more carefully if you have liver, kidney, or heart problems or have diabetes or asthma.

Let your doctor know your medical history to make sure it is safe for you. Check with your doctor about all other medicines that may affect, or be affected by, this medicine. You will probably have several tests both before and during treatment to check your womb. This medicine can alter your thinking or reactions, and you may feel very tired, so be careful if you drive or need to be alert.

Uses of Srgest Capsule

Benefits of Srgest Capsule

Female infertility
Srgest 300mg Capsule contains progesterone, a female hormone that is important in the regulation of ovulation and menstruation. It is used to cause menstrual periods in women who have not reached menopause but are not having periods due to a lack of natural progesterone in the body. Progesterone helps to prepare the uterus for pregnancy by causing the uterus lining (endometrium) to thicken. This increases the chance of a successful pregnancy. You should use the medicine as prescribed for it to be effective. You may be asked to continue with this treatment for a period after becoming pregnant.

Hormone replacement therapy
Hormone Placement Therapy (HRT) is a treatment to relieve symptoms of menopause such as hot flushes, night sweats, mood swings, vaginal dryness and reduced sex drive. Since menopause can last for several years, this treatment can make a big improvement to your daily life and mood. You should use this medicine as it is prescribed, and for as long as it is prescribed by your doctor.

Side effects of Srgest Capsule

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Srgest

Headache
Breast pain
Irregular menstrual cycle
Abdominal cramp
Bloating
Nausea
Vomiting
Hair loss
Vaginal yeast infection

How to use Srgest Capsule

Take this medicine in the dose and duration as advised by your doctor. Srgest 300mg Capsule is to be taken on an empty stomach.

How Srgest Capsule works

Srgest 300mg Capsule works by preparing the uterus for pregnancy and maintaining a healthy environment for fetal development. It thickens the uterine lining to support implantation and prevents contractions that could lead to early pregnancy loss. Additionally, it helps regulate the menstrual cycle and balances other reproductive hormones. In hormone therapy, it supports overall hormonal stability and helps manage symptoms related to hormonal imbalances.

Quick tips

Srgest 300mg Capsule helps regulate menstrual cycles, treats heavy bleeding, and prevents thickening of the uterus.
Srgest 300mg Capsule is also used to restore menstruation in women with secondary amenorrhea (the absence of menstrual cycles).
Srgest 300mg Capsule is best taken without food, preferably in the evening or at bedtime.
It may cause sleepiness or drowsiness. Do not drive or do anything that requires mental focus until you know how Srgest 300mg Capsule affects you.
It may cause bleeding or spotting between menstrual periods. Let your doctor know if this occurs frequently.

Safety advice

Alcohol

UNSAFE

Do not drink alcohol while you are taking this medicine. Srgest 300mg Capsule may cause excessive drowsiness when taken with alcohol.

Pregnancy

CONSULT YOUR DOCTOR

Srgest 300mg Capsule is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

CONSULT YOUR DOCTOR

Srgest 300mg Capsule may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

Driving

UNSAFE

Srgest 300mg Capsule may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CONSULT YOUR DOCTOR

There is limited data available on the use of Srgest 300mg Capsule in patients with kidney disease. Please consult your doctor.

Liver

CAUTION

Srgest 300mg Capsule should be used with caution in patients with liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Srgest with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Severe

Darunavir (Oral Route)

It is recommended to use barrier methods (like condoms), IUDs, or a depot for contraception. Your doctor may monitor your treatment closely and adjust the doses as per the observations. Use barrier methods (like condoms) for contraception to reduce the risk of HIV infection.

Severe

Mycophenolate mofetil (Oral Route)

Effective contraception must be used before, during, and for at least 6 weeks after stopping Mycophenolate mofetil. It is recommended to consult your doctor. Mycophenolate mofetil may reduce the efficacy of Progesterone.

Severe

Perampanel (Oral Route)

Severe

Saquinavir (Oral Route)

Severe

Tamoxifen (Oral Route)

Do not consume Tamoxifen with Progesterone if you have or had breast cancer. If essential, consult your doctor.

Frequently asked questions

Does Srgest 300mg Capsule cause weight gain?

Yes, taking Srgest 300mg Capsule may cause weight gain. The weight gain may be due to water retention and may not be a serious sign. However, contact your doctor in case your weight gain is worrying you. The risk of weight gain is generally less if Srgest 300mg Capsule is taken with estrogen as a combined pill. But, do not start any hormonal therapy without consulting your doctor.

How is progesterone beneficial for fertility and pregnancy?

Progesterone is a very important hormone in fertility. It is a hormone secreted by the ovaries that helps prepare and maintain the uterus for pregnancy. Srgest 300mg Capsule (a form of progesterone) is given as a medicine in cases of infertility to support the uterus in preparing itself for the pregnancy and to prevent abortions in some cases. It is also used to prevent premature labor.

Fact Box

Chemical Class

Gluco/mineralocorticoids, progestogin derivative

Habit Forming

Therapeutic Class

GYNAECOLOGICAL

Action Class

Natural Progesterone

Related lab tests

Anti Mullerian Hormone

Glycosylated Hemoglobin

Testosterone Total

Thyroid Stimulating Hormone

References

Chrousos GP. The Gonadal Hormones & Inhibitors. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 706-707.
Levin ER, Hammes SR. Estrogens and Progestins. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1180-85.
Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 03 Apr. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 04 Apr. 2019] (online) Available from:
Progesterone [Prescribing Information]. St. Petersburg, FL: Catalent Pharma Solutions; 2009. [Accessed 28 Mar. 2023] (online) Available from:
Progesterone [Prescribing Information]. Hyderabad, India: Eugia Pharma Specialities Limited; 2024. [Accessed 04 Mar. 2024] (online) Available from:

User feedback

Patients taking Srgest 300mg Capsule

Once A Day

73%

Twice A Day

18%

Thrice A Day

What are you using Srgest Capsule for?

Hormone replacement therapy

100%

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Ordain Health Care Global Pvt Ltd
Address: Exeltis - Ordain Health Care Global Pvt Ltd , Khivraj Complex - II, 4th Floor, No: 480, Anna Salai, Nandanam, Chennai - 600 035, Tamil Nadu, India.

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Srgest 300mg Capsule

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Srgest Capsule

Benefits of Srgest Capsule

Side effects of Srgest Capsule

How to use Srgest Capsule

How Srgest Capsule works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Darunavir (Oral Route)

Mycophenolate mofetil (Oral Route)

Perampanel (Oral Route)

Saquinavir (Oral Route)

Tamoxifen (Oral Route)

Frequently asked questions

Does Srgest 300mg Capsule cause weight gain?

How is progesterone beneficial for fertility and pregnancy?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Anti Mullerian Hormone

Glycosylated Hemoglobin

Testosterone Total

Thyroid Stimulating Hormone

References

User feedback

Patients taking Srgest 300mg Capsule

What are you using Srgest Capsule for?

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

Related/Popular tests