Information about Perampanel

Perampanel Uses

Perampanel is used to prevent seizures.

How Perampanel works

Perampanel is an antiepileptic medication. It prevents seizures in patients with epilepsy by blocking a receptor in the brain known as the glutamate receptor, thereby suppressing the abnormal and excessive activity of the nerve cells in the brain.

Common side effects of Perampanel

Dizziness, Sleepiness, Fatigue, Anger, Fall, Nausea, Weight gain, Vertigo, Impaired coordination, Altered walking, Balance disorder (loss of balance)
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Last updated:
16 Mar 2020 | 12:04 PM (UTC)
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Available Medicine for Perampanel

FycompaEisai Pharmaceuticals India Pvt Ltd
245 to ₹21525 variant(s)

Expert advice for Perampanel

  • Take your medication regularly as directed by your doctor as missing doses can trigger seizures.
  • Do not change the brand of your medicine and make sure that you have sufficient amount of medicine present with you.
  • Some healthy tips to prevent seizures:
    • Take a healthy diet along with regular exercise.
    • Practice yoga every day.
    • Get enough sleep at nighttime.
    • Limit the use of screen time such as mobile/ laptop.
    • Take your medication on time.
  • Do not drive or do anything that requires mental focus until you know how Perampanel affects you.
  • It may cause weight gain. Hence, monitor your weight regularly.
  • Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts or behavior.
  • Do not stop taking the medication suddenly without talking to your doctor as it may increase the seizure frequency.

Frequently asked questions for Perampanel


Q. Does Perampanel have abuse potential?

Yes, Perampanel has abuse potential in addition to its rewarding psychological or physiological effects. If a patient has a history of drug abuse then monitoring for Perampanel abuse should be done.

Q. What are the most serious side effects of Perampanel?

Perampanel may cause some serious psychiatric and behavioral side effects such as aggression, hostility, irritability, anger, and suicidal and murderous thoughts.

Q. What are the withdrawal symptoms of Perampanel?

Perampanel may cause physical dependence which means that suddenly stopping it may cause withdrawal symptoms which include anxiety, nervousness, irritability, fatigue, weakness, lethargy, mood swings, and sleeplessness.

Q. Does Perampanel cause weight gain?

Yes, Perampanel may cause weight gain. It is a common side effect of Perampanel. Talk to a dietician if you start gaining weight while taking Perampanel.

Q. What should I avoid while taking Perampanel?

Perampanel may cause sleepiness and dizziness, so alcohol consumption should be avoided as it may make you more sleepy and dizzy. You should avoid driving and using heavy machinery until and unless you know how Perampanel affects you. You should also avoid getting pregnant and breastfeeding your baby.

Q. Can I crush Perampanel or cut it into half?

No, you should not stop taking perampanel without consulting your doctor. Discontinuing the use of perampanel suddenly or reducing its dose significantly may lead to unpleasant effects

Q. Can I stop taking Perampanel on my own?

No, you should not stop taking Perampanel without consulting your doctor. Sudden discontinuity of Perampanel or significant dose reduction may cause occurrence of unpleasant effects.


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