Sortex 20mg Capsule

Reviewed By Dr. Mekhala Chandra, MD, MBBS

Last updated on 19 Jan 2026 | 06:30 PM (IST)

Sortex 20mg Capsule belongs to a group of medicines called retinoids (vitamin A derivative). It is used to treat severe acne that has not responded to other treatments.

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₹155 MRP ₹175.3112% off

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Sortex 20mg Capsule

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₹155

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Same composition

Clinsol I 20mg Capsule

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Isotretinoin (20mg)

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General Information

Contains

Isotretinoin (20mg)

Marketer

Osnat Pharmaceuticals

Storage

Store below 30°C

The content is shown in English

Product introduction

Sortex 20mg Capsule should be used in the dose and duration as advised by your doctor. Take it with or without food, preferably at the same time each day to avoid a missed dose. It may take several weeks for your symptoms to improve but keep taking the medicine regularly to get the most benefit. If you notice no improvement after a few weeks, see your doctor again.

The most common side effects include dry skin, rash, and increased liver enzymes. They are not usually serious and often disappear after getting used to the medicine but if they bother you or do not go away, tell your doctor.

Sortex 20mg Capsule may make you more sensitive to sunlight so you should limit your exposure to the sun. It may also make your skin more fragile. Avoid any waxing (hair removal), or laser treatments during treatment. Additionally, it may cause dryness of the mouth, lips, and eyes so drink plenty of water and use a moisturizer. This medicine may lead to birth defects, do consult your doctor if you are pregnant or planning pregnancy.

Uses of Sortex Capsule

Treatment of Acne

Benefits of Sortex Capsule

Treatment of Acne
Sortex 20mg Capsule helps treat acne by reducing the production of sebum (a natural substance) that causes acne. This kills acne-causing bacteria and prevents spots or pimples from appearing. It usually takes a few weeks to have a noticeable effect so keep taking it even if it appears not to be working. Sometimes acne may get worse before it gets better, however, with proper use, your skin will get clearer. This medicine will help improve your mood and uplift your confidence as your skin becomes acne-free.

Side effects of Sortex Capsule

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Sortex

Increased liver enzymes
Rash
Dry skin

How to use Sortex Capsule

Take this medicine in the dose and duration as advised by your doctor. Sortex 20mg Capsule may be taken with or without food.

How Sortex Capsule works

Sortex 20mg Capsule is a derivative of vitamin A. It acts on glands (sebaceous) to reduce the production of a natural substance (sebum) that causes acne. Also, the controlled sebum production kills acne-causing bacteria. It also works as an anti-inflammatory to decrease inflammation (redness and swelling).

All substitutes for Sortex 20mg Capsule

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

You have been prescribed Sortex 20mg Capsule for the treatment of severe acne.
Take it with food.
Avoid exposure to sunlight while using Sortex 20mg Capsule. Use protective measures such as sunscreen or protective clothing.
Avoid face waxing and laser treatment while using this medicine as it makes your skin more fragile.
It may cause dryness of mouth, lips, and eyes. Drink plenty of water, use moisturiser and avoid wearing contact lenses. Inform your doctor if it bothers you.
Do not take Sortex 20mg Capsule if you are pregnant, planning pregnancy or breastfeeding.

Safety advice

Alcohol

CAUTION

Alcohol should be used with caution while taking Sortex 20mg Capsule.

Pregnancy

UNSAFE

Sortex 20mg Capsule is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.

Breast feeding

UNSAFE

Sortex 20mg Capsule is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving

UNSAFE

Sortex 20mg Capsule may cause temporary visual disturbances. Do not drive until your vision is clear.

Kidney

CAUTION

Sortex 20mg Capsule should be used with caution in patients with kidney disease. Dose adjustment may be needed.

Liver

UNSAFE

Sortex 20mg Capsule is unsafe to use in patients with liver disease and should be avoided.

Interaction with drugs

Taking Sortex with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Severe

Doxycycline (Oral Route)

Do not consume Isotretinoin with Doxycycline.

Severe

Demeclocycline (Oral Route)

Do not consume Isotretinoin with Demeclocycline.

Severe

Doxycycline (Oral Route)

Do not consume Isotretinoin with Doxycycline.

Severe

Doxycycline (Injection Route)

Do not consume Isotretinoin with Doxycycline.

Severe

Lymecycline (Oral Route)

Do not consume Isotretinoin with Lymecycline.

Frequently asked questions

Is Sortex 20mg Capsule safe to use?

Sortex 20mg Capsule should be used with care since it is associated with significant adverse reactions. It should be used only for patients with severe nodular acne who are unresponsive to conventional therapy, including systemic antibiotics. In addition, Sortex 20mg Capsule should not be used by pregnant women because it can cause severe birth defects.

Is Sortex 20mg Capsule a steroid?

No, Sortex 20mg Capsule is a retinoid (vitamin A) which is used to treat severe types of acne.

What are the recommended tests during Sortex 20mg Capsule therapy?

Your liver enzymes and serum lipids will be checked before the treatment is started. These levels will also be monitored 1 month after the start of treatment and subsequently at 3 monthly intervals unless more frequent monitoring is clinically indicated.

Is the effect of Sortex 20mg Capsule permanent?

It has been observed in many patients that a single 15-20-week course effectively cures the condition and prevents it from coming back. If at all a second course is required, one should wait for at least 8 weeks after completion of the first course. This is because experience with Sortex 20mg Capsule has shown that the symptoms in the patients with acne may continue to improve following treatment with Sortex 20mg Capsule.

Why is Sortex 20mg Capsule so dangerous during pregnancy?

If pregnancy occurs during treatment with Sortex 20mg Capsule then, there is an extremely high risk that the baby may be born with severe birth defects.

Can Sortex 20mg Capsule cause cancer?

No, there are no reports of Sortex 20mg Capsule causing cancer. In fact, it may be useful in some forms of head, skin, and neck cancers.

What are the long-term side effects of Sortex 20mg Capsule?

A normal course of treatment of Sortex 20mg Capsule is 15–20 weeks. Therefore, the long-term effects of low doses have not been studied. However, it may have some effect on bone mineral density. It may decrease bone mineral density in some patients, resulting in osteoporosis or fractures.

Does Sortex 20mg Capsule affect male fertility?

No, Sortex 20mg Capsule does not affect the fertility of male patients. No significant effects were seen on ejaculate volume, sperm count, total sperm motility, morphology, or seminal plasma fructose.

Does Sortex 20mg Capsule damage your liver?

There may be a transient increase in liver enzymes with Sortex 20mg Capsule use. Therefore, regular laboratory tests are required. These values generally return to normal after some time. If the levels remain elevated for a long time, your doctor may discontinue the use of Sortex 20mg Capsule.

Fact Box

Chemical Class

Retinoids

Habit Forming

Therapeutic Class

DERMA

Action Class

First-Generation Retinoids

References

Robertson DB, Maibach HI. Dermatologic Pharmacology. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 1056.
Burkhart C, Morrell D, Goldsmith L. Dermatological Pharmacology. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1812.
Sardana K, Madan A. How to Treat Acne. Sardana K, editor. In: Clinical Approach to Acne Vulgaris. 1st ed. New Delhi: CBS Publishers & Distributors Pvt. Ltd.; 2015. pp. 64-67.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 745-47.
Isotretinoin. Nutley, New Jersey: Roche Laboratories Inc.; 2002. [Accessed on 2 Apr. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 03 Apr. 2019] (online) Available from:
Central Drugs Standard Control Organization. Safety guidelines for isotretinoin. 2018. [Accessed 05 Jul. 2023]. (online) Available from:
Isotretinoin [Prescribing Information]. East Windsor, NJ: Aurobindo Pharma Ltd.; 2024 [Accessed 19 Jan. 2026]. (online). Available from:

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Osnat Pharmaceuticals
Address: LOT NO-108, 379/A, SECTOR-39, WEST, Maloya, Chandigarh, 160025

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Provide right medicines

Prescriptions are complex documents. We proof read and recheck at various steps to provide you the right medication in the correct form and dose

In accordance with the law

Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945

Sortex 20mg Capsule

Save more with additional offers

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Sortex Capsule

Benefits of Sortex Capsule

Side effects of Sortex Capsule

How to use Sortex Capsule

How Sortex Capsule works

All substitutes for Sortex 20mg Capsule

Sotret 20mg Capsule

TRETiva 20 Capsule

aCUTRet 20 Capsule

IsoIN 20 Capsule

Isac 20mg Capsule

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Doxycycline (Oral Route)

Demeclocycline (Oral Route)

Doxycycline (Oral Route)

Doxycycline (Injection Route)

Lymecycline (Oral Route)

Frequently asked questions

Is Sortex 20mg Capsule safe to use?

Is Sortex 20mg Capsule a steroid?

What are the recommended tests during Sortex 20mg Capsule therapy?

Is the effect of Sortex 20mg Capsule permanent?

Why is Sortex 20mg Capsule so dangerous during pregnancy?

Can Sortex 20mg Capsule cause cancer?

What are the long-term side effects of Sortex 20mg Capsule?

Does Sortex 20mg Capsule affect male fertility?

Does Sortex 20mg Capsule damage your liver?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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