Sildaflow 20mg Tablet is a medicine used to treat high blood pressure in the blood vessels that supply the lungs (pulmonary arterial hypertension). It works by relaxing blood vessels, improving blood flow, reducing strain on the heart, and easing symptoms like breathlessness.

Sildaflow 20mg Tablet may be taken on an empty stomach or with a meal, but it should be taken at a fixed time each day. The dose and duration will be decided by your doctor so that you get the right amount to control your symptoms. Follow the advice of your doctor. It is important to take this medicine regularly and for as long as you are advised, even if you feel well. Missing doses may lead to the worsening of your condition.

The most common side effects of this medicine include flushing, headache, muscle pain, diarrhea, pain in limbs, back pain, and blurred vision. If they bother you or if you experience any other side effects, talk to your doctor. They may be able to help you reduce or prevent the side effects.

This medicine can be dangerous to take along with medicines called nitrates (often given for chest pain). Do not take this medicine if you have severe heart or liver problems, if you have recently had a stroke or heart attack, or if you have low blood pressure. Let your doctor know if you suffer from these or any other health problems. Pregnant or breastfeeding women should also consult their doctor before taking it. Avoid drinking alcohol while taking this medicine, as it increases the chances of side effects.

Uses of Sildaflow Tablet

Treatment of Pulmonary arterial hypertension (PAH)

Benefits of Sildaflow Tablet

In Treatment of Pulmonary arterial hypertension (PAH)

Sildaflow 20mg Tablet helps improve breathing in people with pulmonary arterial hypertension (PAH). It helps in relaxing the lung arteries and reduces blood pressure in the lungs, making it easier for the heart to pump blood. This helps relieve breathlessness, fatigue, and dizziness, improving overall quality of life.

Side effects of Sildaflow Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Sildaflow

Flushing (sense of warmth in the face, ears, neck and trunk)
Headache
Blurred vision
Muscle pain
Diarrhea
Indigestion
Limb pain

How to use Sildaflow Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Sildaflow 20mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Sildaflow Tablet works

Sildaflow 20mg Tablet is a phosphodiesterase (PDE-5) inhibitor. It works by relaxing the blood vessels in your lungs, thereby reducing the high blood pressure in the lungs. This allows your heart to work less to pump blood into your lungs.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Sildaflow 20mg Tablet.

Pregnancy

CONSULT YOUR DOCTOR

Sildaflow 20mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CAUTION

Sildaflow 20mg Tablet should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.
Use of Sildaflow 20mg Tablet is not indicated in women.

Driving

UNSAFE

Sildaflow 20mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

SAFE IF PRESCRIBED

Sildaflow 20mg Tablet is safe to use in patients with kidney disease. No dose adjustment of Sildaflow 20mg Tablet is recommended.
However, inform your doctor if you have any underlying kidney disease. A lowering of dose may be considered if it is not well-tolerated.

Liver

CAUTION

Sildaflow 20mg Tablet should be used with caution in patients with severe liver disease. Dose adjustment of Sildaflow 20mg Tablet may be needed. Please consult your doctor.

What if you forget to take Sildaflow Tablet?

If you miss a dose of Sildaflow 20mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Sildaflow 20mg Tablet

₹9.7/Tablet

Vasosure Tablet

Lupin Ltd

₹34.7/tablet

258% costlier

PAH 20 Tablet

MSN Laboratories

₹18.87/tablet

95% costlier

Assurans Tablet

Cipla Ltd

₹25.93/tablet

167% costlier

Pulmoday 20mg Tablet

Aprica Pharmaceuticals Pvt Ltd

₹14.1/tablet

45% costlier

Assurans Tablet

Cipla Ltd

₹19.4/tablet

100% costlier

Quick tips

When taken regularly, Sildaflow 20mg Tablet can help improve your quality of life and exercise ability.
Do not use other medicines (nitrates or nitroglycerin) when taking Sildaflow 20mg Tablet, as it could drop your blood pressure to a dangerous level.
Do not consume alcohol while taking Sildaflow 20mg Tablet, as that may increase the blood pressure-lowering effects of Sildaflow 20mg Tablet.
Stop taking Sildaflow 20mg Tablet and immediately inform your doctor if you notice a loss of vision in one or both eyes or sudden loss of hearing with a ringing sensation in your ear.
Do not stop taking the medication suddenly without talking to your doctor, as that may lead to a worsening of your symptoms.

Fact Box

Chemical Class

Benzenesulfonamide Derivative

Habit Forming

Therapeutic Class

CARDIAC

Action Class

Phosphodiesterase-V (PDE-5) Inhibitors

Interaction with drugs

Taking Sildaflow with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Escitalopram Oxalate (Oral Route) Life-threatening

Do not consume Escitalopram Oxalate with Sildenafil. Concomitant use may affect heart rhythm and may be fatal.

Chlorpromazine (Oral Route) Life-threatening

Do not consume Chlorpromazine with Sildenafil. Concomitant use may affect heart rhythm and can be fatal.

Ranolazine (Oral Route) Life-threatening

Do not consume Ranolazine with Sildenafil. Concomitant use may affect heart rhythm and may be fatal.

Amiodarone (Oral Route) Life-threatening

Do not consume Amiodarone with Sildenafil. Concomitant use may affect heart rhythm and may be fatal.

Pimozide (Oral Route) Life-threatening

Do not consume Pimozide with Sildenafil. Concomitant use may affect heart rhythm and may be fatal.

View all drug interactions

Patient concerns

Having high Pulmonary Atrial Hypertension

Dr. Nabajit Talukdar

Cardiology

What medicines r u on

Hiii my wife having hurt patient ( pulmonary hypertension ) she's taking pulmonext 5mg tablet but this tablet is very costly for me of Rs. 1450/- 10tab. I want to know any another tablet available in same drugs with low price

Dr. Sfurti Mann

Internal Medicine

This can't be decided online Your doctor is the best judge about your patients pulmonary hypertension

Hello Dr. My Dad is facing High Pulmonary Hypertension of 63 and average is 32. He has liver cirrhosis as well, he is advised for liver transplant. As the PAH is high cannot proceed with the surgery. Can you please advise if there is any way out. Age : 49yrs. Medicines for heart taken at present is : Ambrisentan 5mg Assurance 20mg Trimium Inhaler.

Dr. Nabajit Talukdar

Cardiology

Currently no other treatment apart from ambrisantan n assurance will have to wait n see response to medicines if pulmonary pressure comes down only then surgery possible

User feedback

Patients taking Sildaflow 20mg Tablet

Twice A Day

43%

Once A Day

30%

Thrice A Day

26%

What are you using Sildaflow Tablet for?

Erectile dysf*

56%

Others

39%

Pulmonary art*

*Erectile dysfunction, Pulmonary arterial hypertension (PAH)

How much was the improvement?

Average

42%

Excellent

33%

Poor

25%

What were the side-effects while using Sildaflow 20mg Tablet?

Headache

33%

No Side Effec*

33%

Flushing (sen*

33%

*No Side Effect, Flushing (sense of warmth in the face, ears, neck and trunk)

How do you take Sildaflow Tablet?

With food

83%

Empty stomach

17%

Please rate Sildaflow 20mg Tablet on price

Average

61%

Expensive

28%

Not Expensive

11%

FAQs

Can I take Sildaflow 20mg Tablet for the rest of my life?

Sildaflow 20mg Tablet is a prescription medicine and should only be taken for the duration that is advised by your doctor.

Why is the use of Sildaflow 20mg Tablet contraindicated with nitrates?

Use of Sildaflow 20mg Tablet is harmful for patients taking nitrates or blood pressure-lowering medicines, as their combined use can cause a severe fall in blood pressure, which can also result in death.

Why does Sildaflow 20mg Tablet cause a fall in blood pressure (hypotension)?

Sildaflow 20mg Tablet has the property of relaxing the smooth muscle of the blood vessels and widening them, which can cause a fall in blood pressure (hypotension). So, when used with blood pressure-lowering medicines or nitrates, it can cause a severe fall in blood pressure, which could be fatal. Sildaflow 20mg Tablet should not be taken if you are taking nitrates for chest pain or you have a history of heart attack or stroke in the past 6 months.

Is Sildaflow 20mg Tablet safe to use in patients with diabetes?

Yes, if prescribed by your doctor, then Sildaflow 20mg Tablet is safe to use in patients with diabetes.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Michel T, Hoffman BB. Treatment of Myocardial Ischemia and Hypertension. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 752-53.
Katzung BG, Chatterjee K. Vasodilator & the Treatment of Angina Pectoris. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 197.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1261-62.
Sildenafil [Prescribing Information]. New York, New York: Pfizer; 2014]. [Accessed 02 May 2025] (online) Available from:
Sildenafil [Prescribing Information]. Piscataway, NJ: Hetero Labs Limited; 2024. [Accessed 17 Mar. 2025] (online) Available from:

Marketer details

Name: Mankind Pharma Ltd

Address: 208, Okhla Industrial Estate, Phase III, New Delhi - 110020

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.