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MRP: Rs. 110 for 1 bottle(s) (60 ML suspension each)
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Composition for SIBOFIX

Rifaximin(100 mg)

food interaction for SIBOFIX

alcohol interaction for SIBOFIX

pregnancy interaction for SIBOFIX

lactation interaction for SIBOFIX

It can be taken with or without food, but it is better to take it at a fixed time.
Interaction with alcohol is unknown. Please consult your doctor.
It may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The potential benefits may outweigh the risks. Please consult your doctor.
Unknown. Human and animal studies are not available. Please consult your doctor.


Rifaximin(100 mg)


Sibofix suspension is an antibiotic used to treat bacterial infections of the intestine (traveller's  diarrhea). Sibofix suspension is also used to lower the risk of worsened brain function in adults with liver failure. Brain function can be affected when the liver stops working and cannot remove toxic substances from the body.

How it works

Sibofix suspension is a broad spectrum antibacterial drug that fights bacterial infection only in the intestines. Sibofix suspension stops the growth of bacteria that produce toxins and that may worsen liver disease.

Common side effects

Vomiting, Nausea, Abdominal pain, Allergic reaction, Itching, Constipation, Skin rash, Fever, Hypersensitivity reaction


1 Substitutes
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    (60 ML suspension in bottle)
    Merck Ltd
    Rs. 1.79/ML of suspension
    Rs. 107.50
    save 2% more per ML of suspension

Expert advice for SIBOFIX

While you are taking rifaximin, it may cause a reddish discolouration of the urine. This is quite normal. If you are using oral contraceptives take additional precautions while taking rifaximin. Oral contraceptives may not work as well when you are taking this medicine and/or when you have diarrhea. Rifaximin does not normally affect the ability to drive and use machines, but may cause dizziness in some patients. If you feel dizzy you should not drive or operate machinery. if you are pregnant or breast feeding speak to your doctor before starting the drug. To make sure rifaximin is safe for you, tell your doctor if you have:
  • liver disease
  • diarrhea with a fever
  • watery or bloody diarrhea
Treatment with any antibiotic including rifaximin may cause severe diarrhea. You should stop taking it and contact your doctor immediately. Diarrhea may even occur few months after the drug has been stopped.

Frequently asked questions for SIBOFIX


Q. Is rifaximin an antibiotic/ is rifaximin FDA approved for irritable bowel syndrome (IBS)/help in IBS?
Yes, rifaximin (also available as Rifagut) is an antibiotic. It is not yet approved by the FDA for the treatment of IBS.
 Q. Is rifaximin the same as rifampin?
Rifaximin is a structural analog of rifampin.
Q. Is rifagut an antibiotic?
Rifagut is a brand name for rifaximin. Yes, it is an antibiotic.
Q. Can I take xifaxan with amoxicillin/ibuprofen?
Xifaxan is the brand name for rifaximin and can be taken with ibuprofen, but not with amoxicillin, as it is antibiotic. If taken with other antibiotics, rifaximin causes diarrhea.
Q. Does rifaximin cause diarrhea/gas/constipation?
It may rarely cause these side effects.
Q. Does rifaximin kill parasites/yeast?
It is antibiotic and doesn’t kill parasites and yeast.

Top Medicines Prescribed with SIBOFIX SUSPENSION


Content on this page was last updated on 09 September, 2015, by Dr. Varun Gupta (MD Pharmacology)