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Rifaximin is used in the treatment of diarrhoea and hepatic encephalopathy

How it works

Rifaximin kills bacteria by stopping the growth of bacteria that cause infections.

Common side effects

Nausea, Fatigue, Headache, Dizziness, Tenesmus (Urge to defecate but little passage of stool), Abdominal pain, Flatulence, Edema, Difficulty in controlling bowel movements, Ascites (accumulation of fluid in the abdominal cavity)

Available Medicine

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    Sun Pharmaceutical Industries Ltd
    3 variant(s)
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    Torrent Pharmaceuticals Ltd
    3 variant(s)
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    Dr Reddy's Laboratories Ltd
    4 variant(s)
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    Alembic Pharmaceuticals Ltd
    3 variant(s)
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    Cipla Ltd
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    Mankind Pharma Ltd
    2 variant(s)
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    Zydus Cadila
    3 variant(s)
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    Intas Pharmaceuticals Ltd
    3 variant(s)
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    Zuventus Healthcare Ltd
    4 variant(s)
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    Abbott India Ltd
    2 variant(s)

Expert advice

While you are taking rifaximin, it may cause a reddish discolouration of the urine. This is quite normal. If you are using oral contraceptives take additional precautions while taking rifaximin. Oral contraceptives may not work as well when you are taking this medicine and/or when you have diarrhea. Rifaximin does not normally affect the ability to drive and use machines, but may cause dizziness in some patients. If you feel dizzy you should not drive or operate machinery. if you are pregnant or breast feeding speak to your doctor before starting the drug. To make sure rifaximin is safe for you, tell your doctor if you have:
  • liver disease
  • diarrhea with a fever
  • watery or bloody diarrhea
Treatment with any antibiotic including rifaximin may cause severe diarrhea. You should stop taking it and contact your doctor immediately. Diarrhea may even occur few months after the drug has been stopped.

Frequently asked questions



Is rifaximin an antibiotic/ is rifaximin FDA approved for irritable bowel syndrome (IBS)/help in IBS?
Yes, rifaximin (also available as Rifagut) is an antibiotic. It is not yet approved by the FDA for the treatment of IBS


Is rifaximin the same as rifampin?
Rifaximin is a structural analog of rifampin


Is rifagut an antibiotic?
Rifagut is a brand name for rifaximin. Yes, it is an antibiotic

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Can I take xifaxan with amoxicillin/ibuprofen?
Xifaxan is the brand name for rifaximin and can be taken with ibuprofen, but not with amoxicillin, as it is antibiotic. If taken with other antibiotics, rifaximin causes diarrhea


Does rifaximin cause diarrhea/gas/constipation?
It may rarely cause these side effects


Does rifaximin kill parasites/yeast?
It is antibiotic and doesn't kill parasites and yeast.

Content on this page was last updated on 14 February, 2017, by Dr. Varun Gupta (MD Pharmacology)