Sevren 400 Tablet
Prescription Required
Product introduction
Sevren 400 Tablet is used to treat increased phosphate levels in the blood. It is used in patients who are on dialysis due to severe kidney disease. It inhibits the absorption of phosphate from the intestine and lowers the phosphate levels in the blood.
Sevren 400 Tablet should be taken with food. Take it in the dose and duration as advised by your doctor. Take it regularly and at a fixed time each day to get the maximum benefit of the medicine.
Sevren 400 Tablet may cause side effects such as nausea, vomiting, abdominal pain, constipation, and diarrhea. You may also develop low levels of calcium, folic acid, and vitamins A, D, E, and K in your blood. Take necessary supplements as advised by your doctor.
Uses of Sevren Tablet
Side effects of Sevren Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Sevren
- Abdominal pain
- Diarrhea
- Flatulence
- Vomiting
- Constipation
- Nausea
How to use Sevren Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Sevren 400 Tablet is to be taken with food.
How Sevren Tablet works
Sevren 400 Tablet inhibits the absorption of phosphate from the intestine and lower the phosphate levels in the blood.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Sevren 400 Tablet. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Sevren 400 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
SAFE IF PRESCRIBED
Sevren 400 Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
CONSULT YOUR DOCTOR
It is not known whether Sevren 400 Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
SAFE IF PRESCRIBED
Sevren 400 Tablet is safe to use in patients with kidney disease. No dose adjustment of Sevren 400 Tablet is recommended.
However, regular monitoring of calcium levels is advisable in these patients.
However, regular monitoring of calcium levels is advisable in these patients.
Liver
SAFE IF PRESCRIBED
Sevren 400 Tablet is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Sevren 400 Tablet may not be needed in these patients. Please consult your doctor.
What if you forget to take Sevren Tablet?
If you miss a dose of Sevren 400 Tablet, skip it and continue with your normal schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Sevren 400 Tablet
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Quick tips
- Sevren 400 Tablet is used to control blood phosphate level in patients that are on dialysis treatment.
- You must take it with food and stick to the diet prescribed by your doctor.
- You may develop low levels of calcium, folic acid, and vitamins A,D,E, and K in your blood. Your doctor may prescribe supplements, if necessary.
- Avoid taking any other medicine 1 hour before or 3 hours after taking Sevren 400 Tablet.
- Inform your doctor if you have nausea, vomiting, constipation, pain in the abdomen, or if you have undergone any major stomach surgery.
- Sevren 400 Tablet is used to control blood phosphate level in patients that are on dialysis treatment.
- You must take it with food and stick to the diet prescribed by your doctor.
- You may develop low levels of calcium, folic acid, and vitamins A,D,E, and K in your blood. Your doctor may prescribe supplements, if necessary.
- Avoid taking any other medicine 1 hour before or 3 hours after taking Sevren 400 Tablet.
- Inform your doctor if you have nausea, vomiting, constipation, pain in the abdomen, or if you have undergone any major stomach surgery.
Fact Box
Chemical Class
Epoxide
Habit Forming
No
Therapeutic Class
BLOOD RELATED
Action Class
Phosphorous binder
Interaction with drugs
Taking Sevren with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Sevelamer may reduce blood levels of Sparfloxacin.
To take Sparfloxacin, ensure a gap of at least 1 hour before and 3 hours after taking Sevelamer.
Sevelamer may reduce blood levels of Norfloxacin.
To take Norfloxacin, ensure a gap of at least 1 hour before and 3 hours after taking Sevelamer.
Sevelamer may reduce blood levels of Levofloxacin.
To take Levofloxacin, ensure a gap of at least 1 hour before and 3 hours after taking Sevelamer.
Sevelamer may reduce blood levels of Ciprofloxacin.
To take Ciprofloxacin, ensure a gap of at least 1 hour before and 6 hours after taking Sevelamer.
Sevelamer may reduce blood levels of Ofloxacin.
To take Ofloxacin, ensure a gap of at least 1 hour before and 3 hours after taking Sevelamer.
Patient concerns
FAQs
Is Sevren 400 Tablet taken with food?
Yes, Sevren 400 Tablet can be taken with food. It is recommended to take 1-2 tablets (based on individual needs) thrice daily. It is important to take it with meals because Sevren 400 Tablet works by binding to phosphate from food. Take it exactly as advised by your doctor.
Can Sevren 400 Tablet be crushed?
No, you should not crush, chew, or break Sevren 400 Tablet into pieces. You should swallow it as a whole with water.
Why is it important for me to take Sevren 400 Tablet?
It is important to take Sevren 400 Tablet as patients undergoing dialysis cannot control the phosphate levels in their blood, especially after a meal. When the level of phosphate exceeds above the range in the blood, it may cause problems such as itchy skin, red eyes, high blood pressure, bone pain, and also increase the risk of fractures. These increased serum phosphate levels are reduced by Sevren 400 Tablet, as it binds phosphate from food in the digestive tract.
Does Sevren 400 Tablet cause constipation?
A common side effect of Sevren 400 Tablet is constipation, though it does not occur in everyone. The other common side effects of the stomach and intestine include diarrhea, indigestion, flatulence, and pain in the abdomen. Immediately consult your doctor if these side effects become severe and disturb you.
Who should not take Sevren 400 Tablet?
Patients who are allergic to Sevren 400 Tablet and who have low levels of phosphate in blood should avoid taking Sevren 400 Tablet. Additionally, patients having intestinal obstruction should also avoid using Sevren 400 Tablet.
Can I take ciprofloxacin while I am taking Sevren 400 Tablet?
Ciprofloxacin may interfere with the working of Sevren 400 Tablet and therefore it should not be taken at the same time as Sevren 400 Tablet. However, if taken together then a gap of at least 2 hours before or 6 hours after taking Sevren 400 Tablet should be maintained.
How long do I need to take Sevren 400 Tablet?
Continue taking Sevren 400 Tablet as long as recommended by your doctor. Sevren 400 Tablet lowers your dietary phosphate levels but does not cure your disease. Hence, you may have to take it lifelong, as stopping Sevren 400 Tablet may increase your phosphate levels.
Do I need to have any tests while taking Sevren 400 Tablet?
Yes, serum phosphate levels should be monitored regularly while you are taking Sevren 400 Tablet. Also, the use of Sevren 400 Tablet may decrease the levels of vitamin D, A, E, K, and folic acid and hence the levels need to be monitored during the treatment.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 1259.
- Medscape. Sevelamer. [Accessed 6 Apr. 2019] (online) Available from:
- Sevelamer hydrochloride. Guildford, Surrey: SANOFI; 2000 [revised 20 Dec. 2018]. [Accessed 30 Jan. 2019] (online) Available from:
- Sevelamer. Cambridge, USA: Genzyme Corporation; 1998. [Accessed 6 Apr. 2019] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 6 Apr. 2019] (online) Available from:
- Sevelamer Carbonate [Product Information]. Ahmedabad, Gujarat: La Renon. [Accessed 06 Aug. 2023]. (online) Available from:
- National Center for Biotechnology Information. PubChem Compound Summary for , Sevelamer. [Accessed 06 Aug. 2023]. (online) Available from:
Marketer details
Name: Renace Pharmaceuticals
Address: Hannanth Petro Chem (P) Ltd. Basutia, Near HMT D Type Colony, Nainital, Uttarakhand, India
Country of origin: India
The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.
The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.
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