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29 Sep 2020 | 10:25 AM (IST)
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Sevelabind 400mg Tablet

Prescription Required
SALT COMPOSITION
Storage
Store at room temperature (10-30°C)

Introduction

Sevelabind 400mg Tablet is used to treat increased phosphate level in the blood. It is used in patients who are on dialysis due to severe kidney disease. It inhibits the absorption of phosphate from the intestine and lower the phosphate levels in the blood.

Sevelabind 400mg Tablet should be taken with food. Take it in the dose and duration as advised by your doctor. Take it regularly and at a fixed time each day to get maximum benefit of the medicine.

Using of Sevelabind 400mg Tablet may cause side effects such as nausea, vomiting, abdominal pain, constipation and diarrhea. You may also develop low levels of calcium, folic acid and vitamins A, D, E and K in your blood. Take necessary supplements as advised by your doctor.

Uses of Sevelabind Tablet

Benefits of Sevelabind Tablet

In High phosphate levels in blood

Our body needs phosphate for various life functions such as strengthening of bones and teeth, production of energy and forming outer layers of cells in our body called cell membrane. But too much phosphate in our blood can cause serious complications such as heart attack, stroke as well as kidney damage. Sevelabind 400mg Tablet helps to lower the phosphate levels in our blood and prevents these complications particularly in patients who are on dialysis and are unable to get rid of excess phosphate levels through kidneys. Take Sevelabind 400mg Tablet as prescribed by the doctor to get the most of this medicine.

Side effects of Sevelabind Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Sevelabind

  • Nausea
  • Vomiting
  • Upper abdominal pain
  • Flatulence
  • Constipation
  • Diarrhea

How to use Sevelabind Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Sevelabind 400mg Tablet is to be taken with food.

How Sevelabind Tablet works

Sevelabind 400mg Tablet inhibits the absorption of phosphate from the intestine and lower the phosphate levels in the blood.

Safety Advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Sevelabind 400mg Tablet. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Sevelabind 400mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breastfeeding
SAFE IF PRESCRIBED
Sevelabind 400mg Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
CONSULT YOUR DOCTOR
It is not known whether Sevelabind 400mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
SAFE IF PRESCRIBED
Sevelabind 400mg Tablet is safe to use in patients with kidney disease. No dose adjustment of Sevelabind 400mg Tablet is recommended.
However, regular monitoring of calcium levels is advisable in these patients.
Liver
SAFE IF PRESCRIBED
Sevelabind 400mg Tablet is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Sevelabind 400mg Tablet may not be needed in these patients. Please consult your doctor.

What if you forget to take Sevelabind Tablet?

If you miss a dose of Sevelabind 400mg Tablet, skip it and continue with your normal schedule. Do not double the dose.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
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Quick Tips

  • Sevelabind 400mg Tablet is used to control blood phosphate level in patients that are on dialysis treatment.
  • You must take it with food and stick to the diet prescribed by your doctor.
  • You may develop low levels of calcium, folic acid, and vitamins A,D,E, and K in your blood. Your doctor may prescribe supplements, if necessary.
  • Avoid taking any other medicine 1 hour before or 3 hours after taking Sevelabind 400mg Tablet.
  • Inform your doctor if you have nausea, vomiting, constipation, pain in the abdomen, or if you have undergone any major stomach surgery.

Fact Box

Chemical Class
Epoxide
Habit Forming
No
Therapeutic Class
OTHERS

Interaction with Drugs

Taking Sevelabind with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Healgraft, Graftide-M, Mycocel S
SERIOUS
Brand(s): Imunotac, Emgraf, Tacrefite LS
SERIOUS
Brand(s): Imudrops, Neoral, Aurosporine
SERIOUS

Patient Concerns

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##High blood Uric Acid levels.
Shikha Mishra
Dietetics/Nutrition
What exactly u want to know
i have high homocystine levels even my blood levels counts are irregular. how do they affect my health and what should I do about them
Dr. Nabajit Talukdar
Cardiology
Add vit b12 n folic acid tablet cut down carbs n regularly exercisr
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Do you have any questions related to Sevelabind 400mg Tablet ?

User Feedback


FAQs

Q. Is Sevelabind 400mg Tablet taken with food?

Yes, Sevelabind 400mg Tablet can be taken with food. It is recommended to take 1-2 tablets (based on individual needs) thrice daily. It is important to take it with meals because Sevelabind 400mg Tablet works by binding to phosphate from food. Take it exactly as advised by your doctor.

Q. Can Sevelabind 400mg Tablet be crushed?

No, you should not crush, chew, or break Sevelabind 400mg Tablet into pieces. You should swallow it as a whole with water.

Q. Why is it important for me to take Sevelabind 400mg Tablet?

It is important to take Sevelabind 400mg Tablet as patients undergoing dialysis cannot control the phosphate levels in their blood, especially after a meal. When the level of phosphate exceeds above the range in the blood, it may cause problems such as itchy skin, red eyes, high blood pressure, bone pain, and also increase the risk of fractures. These increased serum phosphate levels are reduced by Sevelabind 400mg Tablet, as it binds phosphate from food in the digestive tract.

Q. Does Sevelabind 400mg Tablet cause constipation?

A common side effect of Sevelabind 400mg Tablet is constipation, though it does not occur in everyone. The other common side effects of stomach and intestine include diarrhea, indigestion, flatulence, and pain in abdomen. Immediately consult your doctor if these side effects become severe and disturb you.

Q. Who should not take Sevelabind 400mg Tablet?

Patients who are allergic to Sevelabind 400mg Tablet and who have low levels of phosphate in blood should avoid taking Sevelabind 400mg Tablet. Additionally, patients having intestinal obstruction should also avoid using Sevelabind 400mg Tablet.

Q. Can I take ciprofloxacin while I am taking Sevelabind 400mg Tablet?

Ciprofloxacin may interfere with the working of Sevelabind 400mg Tablet and therefore it should not be taken at the same time as Sevelabind 400mg Tablet. However, if taken together then a gap of at least 2 hours before or 6 hours after taking Sevelabind 400mg Tablet should be maintained.

Q. How long do I need to take Sevelabind 400mg Tablet?

Continue taking Sevelabind 400mg Tablet as long as recommended by your doctor. Sevelabind 400mg Tablet lowers your dietary phosphate levels but does not cure your disease. Hence, you may have to take it life long, as stopping Sevelabind 400mg Tablet may result in an increase in your phosphate levels.

Q. Do I need to have any tests while taking Sevelabind 400mg Tablet?

Yes, serum phosphate levels should be monitored regularly while you are taking Sevelabind 400mg Tablet. Also, the use of Sevelabind 400mg Tablet may decrease the levels of vitamin D, A, E, K, and folic acid and hence the levels need to be monitored during the treatment.

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Disclaimer:

1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 1259.
  2. Medscape. Sevelamer. [Accessed 6 Apr. 2019] (online) Available from:External Link
  3. Sevelamer. Richmond upon Thames, Surrey: Consilient Health Ltd.; 2014 [revised 7 May 2018]. [Accessed 6 Apr. 2019] (online) Available from:External Link
  4. Sevelamer hydrochloride. Guildford, Surrey: SANOFI; 2000 [revised 20 Dec. 2018]. [Accessed 30 Jan. 2019] (online) Available from:External Link
  5. Sevelamer. Cambridge, USA: Genzyme Corporation; 1998. [Accessed 6 Apr. 2019] (online) Available from:External Link
  6. Central Drugs Standard Control Organisation (CDSCO). [Accessed 6 Apr. 2019] (online) Available from:External Link
Expires on or after: February, 2021

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