Sentral 25mg Tablet is a type of antidepressant belonging to the selective serotonin reuptake inhibitor (SSRI) group of medicines. It is prescribed for depression and anxiety-related conditions like panic disorder, obsessive-compulsive disorder, and post-traumatic stress disorder (PTSD).

Sentral 25mg Tablet is also used to treat premenstrual dysphoric disorder (depression and irritability before menstrual period in women). It can be taken with or without food. The dose and how often you need it will be decided by your doctor so that you get the right amount to control your symptoms.

Your doctor may start you on a lower dose and increase it gradually. Do not change the dose or stop taking it without talking to your doctor, even if you feel well. Doing so may make your condition worse or you may suffer from unpleasant withdrawal symptoms (anxiety, restlessness, palpitations, dizziness, sleep disturbances, etc).

To get the most benefit, take this medicine regularly at the same time each day. Your doctor may advise you to take it in the morning if you have trouble sleeping. It may take a few weeks before you start feeling better. Let your doctor know if you do not see any improvement even after 4 weeks.

Some common side effects of Sentral 25mg Tablet include nausea, indigestion, loss of appetite, increased sweating, tremors, insomnia (difficulty in sleeping), and diarrhea. Sexual side effects like decreased sexual drive, delayed ejaculation, and erectile dysfunction may also be seen. Let your doctor know straight away if you develop any sudden worsening of mood or any thoughts about harming yourself.

Before taking this medicine, you should tell your doctor if you have epilepsy (seizure disorder or fits), diabetes, liver or kidney disease, heart problems, or glaucoma. These may affect your treatment. Pregnant or breastfeeding women should also consult their doctor before taking it. Some other medicines may affect the way it works, especially other antidepressants and medicines called MAO inhibitors. Please tell your doctor about all the medicines you are taking to make sure you are safe.

Uses of Sentral Tablet

Depression
Panic disorder
Premenstrual dysphoric disorder
Anxiety disorder

Benefits of Sentral Tablet

In Depression

Sentral 25mg Tablet works by increasing the level of a chemical called serotonin in the brain. This improves your mood, relieves anxiety, tension, and helps you sleep better. It has fewer side effects than older antidepressants. It usually takes 4-6 weeks for this medicine to work so you need to keep taking it even if you feel it is not working. Do not stop taking it, even if you feel better unless your doctor advises you to.

In Panic disorder

Sentral 25mg Tablet can help relieve symptoms of many panic disorders including panic attacks. It can help you feel calmer and improve your ability to deal with problems. Do not stop taking it, even when you feel better, unless your doctor advises you to.

In Premenstrual dysphoric disorder

Sentral 25mg Tablet helps relieve depression and irritability that may occur in women before menstrual periods. It helps you feel calm and improves your mood. Keep taking the medicine until your doctor advises you to stop.

In Anxiety disorder

Sentral 25mg Tablet helps relieve symptoms of many anxiety disorders including obsessive-compulsive disorder and generalised anxiety disorder by increasing the level of a chemical called serotonin in your brain. It has fewer side effects than older antidepressants and is normally taken once a day. It helps you feel calm with a better ability to deal with problems. Exercise and a healthy diet can also improve your mood. Keep taking the medicine until your doctor advises you to stop.

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Side effects of Sentral Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Sentral

Delayed ejaculation
Erectile dysfunction
Indigestion
Insomnia (difficulty in sleeping)
Low sexual desire
Nausea
Tremor
Diarrhea
Increased sweating
Loss of appetite

How to use Sentral Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Sentral 25mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Sentral Tablet works

Sentral 25mg Tablet is a selective serotonin reuptake inhibitor (SSRI) antidepressant. It works by increasing the levels of serotonin, a chemical messenger in the brain. This improves mood and physical symptoms of depression and also relieves symptoms of post traumatic stress disorder, obsessive-compulsive disorder, panic disorder, premenstrual dysphoric disorder and anxiety.

Safety Advice

Alcohol

UNSAFE

Sentral 25mg Tablet may cause excessive drowsiness with alcohol.

Pregnancy

CONSULT YOUR DOCTOR

Sentral 25mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breastfeeding

CONSULT YOUR DOCTOR

Sentral 25mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

UNSAFE

Sentral 25mg Tablet may cause side effects which could affect your ability to drive.

Kidney

SAFE IF PRESCRIBED

Sentral 25mg Tablet is safe to use in patients with kidney disease. No dose adjustment of Sentral 25mg Tablet is recommended.
However, inform your doctor if you have an underlying kidney disease as you may be given a smaller dose initially and then increased slowly as required.

Liver

CAUTION

Sentral 25mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Sentral 25mg Tablet may be needed. Please consult your doctor.
Use of Sentral 25mg Tablet is not recommended in patients with severe liver disease.

What if you forget to take Sentral Tablet?

If you miss a dose of Sentral 25mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.

Sentral 25mg Tablet

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Quick Tips

Do not drive or do anything requiring concentration until you know how Sentral 25mg Tablet affects you.
Talk to your doctor if you notice sudden mood changes or develop suicidal thoughts.
The addiction/dependence potential of Sentral 25mg Tablet is very less.
Inform your doctor if you experience decreased sex drive or difficulty having an orgasm.
Do not stop taking the medication suddenly without talking to your doctor.

Fact Box

Chemical Class

Tametraline Derivative

Habit Forming

Therapeutic Class

NEURO CNS

Action Class

Selective Seretonin Reuptake inhibitors (SSRIs)

Interaction with Drugs

Taking Sentral with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Linezolid

Brand(s): Lizolan, Lidoford, Zenlid

LIFE-THREATENING

Moclobemide

Brand(s): Trima, Rimarex, Morex

LIFE-THREATENING

Rasagiline

Brand(s): Rasalect, Relgin, Rasipar

LIFE-THREATENING

Reboxetine

Brand(s): Rebotin

LIFE-THREATENING

View all interactions

Patient Concerns

PANIC ATTACK ANXIETY DISORDER T

Dr. Jyoti Kapoor Madan

Psychiatry

Anxiety is the result of a hyperarousal state of nervous system due to a low threshold for threat perception. In simpler words, it's an ongoing flight or fight response. It can elicit a neuro-hormonal response understood as Flight or Fright reaction kicking in physiological cascade of symptoms ranging from palpitations, tachycardia, breathlessness, increased bowel movement, increase frequency of urination, dizziness, muscle tension or pain, trembling, dizziness, blurring of vision to restlessness, confusion and fainting spells. Chronic stress causes prolonged anxiety response with the consequences of slowed me ration, lack of concentration, headaches, fluctuations in blood pressure and increased wear and tear of body tissues. Identifying your stressors, learning to deal with them, de stressing regularly by doing something that makes one feel good, yoga and meditation are some non pharmacological strategies to deal with it. If the condition is persisting for a long time, it's better to see a psychiatrist.

Mental Depression , Anxiety disorder

Dr. Jyoti Kapoor Madan

Psychiatry

Depression is a persistent state of sadness that is the result of interaction between one's inner biological and psychological state and gets triggered of with environmental stressors. Reactive depression is in response to a situation like loss, sickness, trauma etc. Endogenous depression occurs without any noticeable environmental stressors. Psychological symptoms include lack of interest, negative thinking, irritability, frustration, feeling demotivated etc. Somatic symptoms like fatigue/ weakness/ lack of sleep/ lack of appetite and other physical symptoms are common. Anxiety is common. In severe cases one may feel helpless and hopeless enough to wish for death or attempt suicide. Treatment includes physical and psychiatric work up following which medicines can be prescribed. In milder cases, psychotherapy or counselling is recommended.

Mixed anxiety depressive disorder

Dr. Jyoti Kapoor Madan

Psychiatry

I am suffering from acute anxiety disorder and panic attack kindly suggest me I am suffering from acute anxiety disorder and panic attack kindly suggest me

Dr. Manju Singh

Homeopathy

Dear PATIENT the basis of information you have provided you can consider following homeopathic medicine:Gelsemium 30, Dilution, ADEL Dosage: 4 drops in 1 teaspoon of water, 3 times a day. LINK: http://www.1mgayush.com/products/Gelsemium./Standard

What are possible physical symptoms of anxiety disorder and depression.

Dr. Subrata Naskar

Psychiatry

Hi PATIENT me clear that for you. Depression is usually associated with a lot of physical symptoms like increased fatigue, decreased amount of sleep or interrupted sleep, loss of appetite usually cause more than 5% body weight loss, loss of libido. But its effect is mainly psychological whivh causes persist low mood, inability to enjoy pleasurable activities, low self esteem, bleak view of the future, guilty feeling etc. These symptoms have to be present persistently for 2 weeks to be called depression. On the other hand, anxiety has two main components, worry and fear. The common physical complaints are extreme sweating, butterfly like feeling in stomach, fidgetiness, increased frequency of urination. If associated with panic attacks, there is often palpitation, respiratory distress, dryness of throat, a sense of doom. Anxiety disorders are of various types and each have varied specific set of symptoms, but these are usually in common.

I had sleep disorder due to panic disorder. Every day feeling discomfort of gastric die to not getting sound sleep

Dr. Jyoti Kapoor Madan

Psychiatry

Sleep problems are often caused by underlying physical and/ or psychological cause. This requires examination of the patient so that proper treatment can be initiated. Often stress/ anxiety/ depression or mood disorder needs to be dealt with and sleeping pills are not adequate treatment. Please go through the link below for further understanding- Sleep Disorders ? Demythifying http://drjyotikapoor.com/2015/01/26/sleep-disorders/

Do you have any questions related to Sentral 25mg Tablet ?

CONSULT A DOCTOR ONLINE

FAQs

Q. Does Sentral 25mg Tablet cause weight gain?

Sentral 25mg Tablet commonly causes weight gain as the patient is unable to stop the urge to eat. Additionally, use of Sentral 25mg Tablet may also lead to weight loss, though it occurs rarely. The reason for weight loss could be loss of appetite. Consult your doctor in case of any concerns regarding your weight.

Q. How long does it take for Sentral 25mg Tablet to work?

You may start noticing an improvement in symptoms within 7 days of taking Sentral 25mg Tablet. However, it may take longer to show full response and will vary from person to person.

Q. How long do I need to take Sentral 25mg Tablet?

You should continue taking Sentral 25mg Tablet as long as your doctor recommends to take it which may be for several months. Doctors usually recommend the medicine for 6 months to a year after you no longer feel depressed. It is important to know that stopping the medication before the suggested time may cause depression to come back.

Q. When is the best time to take Sentral 25mg Tablet?

Sentral 25mg Tablet is usually taken once a day and can be taken at any time of the day. It can be taken with or without food. Take it as per your convenience but preferably at the same time each day. Some people who have sleep difficulty after taking Sentral 25mg Tablet, they should take it in the morning. Whereas, some take it at night to limit the side effects of nausea and vomiting.

Q. Does Sentral 25mg Tablet cause sleepiness?

Yes, Sentral 25mg Tablet may commonly cause sleepiness. In case you feel dizzy, sleepy or tired after taking Sentral 25mg Tablet, you should avoid driving or using heavy machinery. This generally happens within the first few days and weeks after starting Sentral 25mg Tablet, which may disappear after 2-3 months of use of Sentral 25mg Tablet.

Q. What does Sentral 25mg Tablet do for anxiety?

Sentral 25mg Tablet belongs to selective serotonin reuptake inhibitor (SSRI) class of medicines. It increases the levels of serotonin which is an important chemical and a neurotransmitter. This increase in serotonin levels can help to improve and regulate your mood, resulting in an improvement in the symptoms of anxiety.

Q. Can I stop taking Sentral 25mg Tablet if I am better now?

No, you should not stop taking Sentral 25mg Tablet without consulting your doctor. This is because sudden discontinuation of Sentral 25mg Tablet may cause withdrawal symptoms. Hence, it is important to gradually reduce the dose with time (over several weeks or months).

Q. What are the withdrawal symptoms of Sentral 25mg Tablet?

The withdrawal symptoms of Sentral 25mg Tablet include dizziness, nausea, numbness or tingling in the hands or feet, trouble sleeping, feeling agitated or anxious, headaches and shaking. However, these symptoms are generally mild to moderate and disappear after 1-2 weeks of discontinuing Sentral 25mg Tablet.

Q. What are the symptoms of overdose of Sentral 25mg Tablet?

The symptoms of overdose of Sentral 25mg Tablet include nausea, dizziness, fever, vomiting, confusion, shakiness, and a rapid heartbeat. Whereas, serious side effects include fainting, delirium, heart problems, and changes in blood pressure. If you experience such symptoms immediately contact your doctor or seek emergency medical services in a nearby hospital.

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Disclaimer:

1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Stahl SM, editor. Sertraline. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 625-30.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1253-58.
Sertaline.New York, New York: Pfizer; [revised May 2014]. [Accessed 22 Mar. 2019] (online) Available from:
Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 22 Mar. 2019] (online) Available from:
Sertaline. Beverley, Hull: Dr. Reddy's Laboratories (UK) Ltd.; 2008 [revised 18 Apr. 2018]. [Accessed 22 Mar. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 22 Mar. 2019] (online) Available from:

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