Ributin Capsule is an antibiotic, used in the treatment of tuberculosis with HIV (human immunodeficiency virus) infection. It helps to fight germs (bacteria) called mycobacteria, which cannot be destroyed by other antibiotics in people who have a weaker immunity.

Ributin Capsule may be used alone or in combination with other medicines to help prevent serious infections caused by microorganisms like mycobacterium avium complex (MAC). It should be taken in the dose and duration as advised by the doctor. This medicine should be taken on an empty stomach. It is better to take it at the same time each day to get the most benefit and you should keep on taking this medicine for as long as you are prescribed. Stopping it early may make the infection to come back and harder to treat.

Some people may develop side effects like decreased white blood cells, anemia, rash, nausea, and fever. These side effects are usually temporary and go away during treatment as your body adjusts to the medicine. Consult your doctor if these side effects bother you or do not go away.

Before starting treatment with this medicine, you should tell your doctor if you are pregnant, breastfeeding, or suffering from any liver, kidney, or heart problems or if you are allergic to any medicine. You may be regularly monitored with blood tests and chest x-rays to check that you do not have active tuberculosis or any other mycobacterial disease. Your doctor may advise for regular eye examination and liver function tests while using it.

Uses of Ributin Capsule

Tuberculosis with HIV infection

Benefits of Ributin Capsule

In Tuberculosis with HIV infection

Ributin Capsule helps treat Mycobacterium avium complex disease (MAC; a bacterial infection that may cause serious symptoms) in patients with human immunodeficiency virus (HIV) infection. It kills as well as stops the growth of infection causing bacteria and helps in treating the infection. Take it in the dose and duration advised by the doctor. Your symptoms may improve before the infection is completely cured. Do not stop taking it without consulting your doctor as doing so may cause the infection to return or worsen. Follow your doctor’s instructions carefully to get maximum benefit.

Side effects of Ributin Capsule

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Ributin

Nausea
Rash
Fever
Anemia (low number of red blood cells)
Decreased white blood cell count

How to use Ributin Capsule

Take this medicine in the dose and duration as advised by your doctor. Ributin Capsule is to be taken empty stomach.
Avoid Ributin Capsule with acidic food and beverages such as sugar, certain dairy products, fish, processed foods, fresh meats and processed meats,sodas and other sweetened beverages.

How Ributin Capsule works

Ributin Capsule works by inhibiting an enzyme DNA-dependent RNA polymerase in bacteria, leading to the suppression of RNA synthesis that is required for survival and this leads to cell death of infection-causing bacteria. This helps treat Mycobacterium avium complex disease (tuberculosis) in patients with human immunodeficiency virus (HIV) infection.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Ributin Capsule. Please consult your doctor.

Pregnancy

SAFE IF PRESCRIBED

Ributin Capsule is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Breast feeding

SAFE IF PRESCRIBED

Ributin Capsule is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Driving

SAFE

Ributin Capsule does not usually affect your ability to drive.

Kidney

CAUTION

Ributin Capsule should be used with caution in patients with severe kidney disease. Dose adjustment of Ributin Capsule may be needed. Please consult your doctor.

Liver

CAUTION

Ributin Capsule should be used with caution in patients with severe liver disease. Dose adjustment of Ributin Capsule may be needed. Please consult your doctor.

What if you forget to take Ributin Capsule?

If you miss a dose of Ributin Capsule, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

No substitutes found for this medicine

Quick tips

Ributin Capsule is used to treat tuberculosis in patients with HIV.
Seek immediate medical attention if you develop sudden wheeziness, difficulty in breathing, pain in the chest, swelling of eyelids, face, or lips, rash or itching.
Taking Ributin Capsule may change the color of your urine to red/orange. You may also experience coloring of the skin and other body fluids and also of soft contact lenses.
You may be regularly monitored with blood tests and chest X-rays to check that you do not have active tuberculosis or any other mycobacterial disease.
You may also undergo regular eye examinations while using Ributin Capsule.
Use non-hormonal birth control techniques (condom, diaphragm with spermicide) to prevent pregnancy, as Ributin Capsule can make birth control pills less effective.

Fact Box

Chemical Class

Macrolactams

Habit Forming

Therapeutic Class

ANTI INFECTIVES

Action Class

RNA polymerase inhibitors- Rifamycins

Interaction with drugs

Taking Ributin with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Sirolimus

Brand(s): Rapasim, Siropan, Rapacan

Life-threatening

Acenocoumarol

Brand(s): Altrom, Cenorol, Cgtrom

Serious

Aripiprazole

Brand(s): Arifril, Biozol, Elrip

Serious

Atazanavir

Brand(s): Atazor

Serious

View all interactions

Patient concerns

i have unprotected sex with my friend. Can I take any drugs now to prevent any STD/HIV infection

Dr. Shyam Gupta

Obstetrics and Gynaecology

Hello PATIENT to 1mg. There is some medicine for prophylactic but you need to see physician for prescription and better you check HIV status of both partner

hello, one of my frnd suffering with hiv infection from last 2yrs her cd4 is more than 470 and viral load is zero undetectable now she is using art medicines i have doubt that can we have to use art medicine in the whole life or can we stop it once we get viral load zero

Dr. Atula Gupta

Dermatology

You still need to be on ART even if the viral load is undetectable

He is suffering from Lungs problem Actually he's a smoker & Diabetic. Before 2 week his left lung was collapsed and left lung got shrink . Doctor had done chest tube & after he got pneumonitis doctor has starting Antibiotic(Tazomac 4.5gm TDS +linezolid 600 BD) with Nebulizer of Foracort & Duolin + Doxyphillin 400 tab.TDS Doctor gave this treatment for 10 day after . After this CBC was Normal. but chest tube Bag was bubbling . Doctor remove chest tube becoz the Bag was looking normal But after three Days lungs collapse and Again Doctor Is doing same process . I am attaching report (CECT, Sputum complete Examination , CBC ,Blood culture etc.) with this. Please guide me the Better way to improve. What shoul we do.

Dr. Sunil Sekhri

Diabetology

Patient has Pneumothorax with pleural effusion and mild pericardial effusion. there are cavitation in lungs. cause could be Tuberculosis, Malignancy, fungal infection most likely. You need to consult a Doctor specialising in respiratory diseases.

User feedback

Patients taking Ributin Capsule

Once A Day

89%

Twice A Day

11%

What are you using Ributin Capsule for?

Tuberculosis *

57%

Tuberculosis *

29%

Others

14%

*Tuberculosis with HIV infection, Tuberculosis (TB)

How much was the improvement?

Average

67%

Excellent

33%

What were the side-effects while using Ributin Capsule?

Muscle pain

50%

Rash

25%

No Side Effec*

25%

*No Side Effect

How do you take Ributin Capsule?

Empty stomach

50%

With food

50%

Please rate Ributin Capsule on price

Expensive

50%

Average

50%

Related lab tests

HIV 1 - Quantitative (Viral Load)

HIV 1 And 2 Antibody - ELISA

Mycobacterium Tuberculosis DNA PCR - Qualitative

Top Physicians

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4.4 ★

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Gumbo T. Chemotherapy of Tuberculosis, Mycobacterium Avium Complex Disease, and Leprosy. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1550-554.
Chambers HF, Deck DH. Antimycobacterial Drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 829.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1212-13.
Rifabutin. Sandwich, Kent: Pfizer Limited; 2003 [revised Dec. 2015]. [Accessed 25 Jan. 2019] (online) Available from:
Medscape. Rifabutin. [Accessed 01 Apr. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 01 Apr. 2019] (online) Available from:

Manufacturer/Marketer address

Lupin Ltd, 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India

Country of origin: India

NOT FOR SALE

We do not facilitate sale of this product at present