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Repa X1 Tablet

Written By Dr. Swati Mishra, BDS
Reviewed By Dr. Mekhala Chandra, MD, MBBS
Last updated on 19 Jan 2026 | 04:21 PM (IST)
Repa X1 Tablet is used to lower blood sugar levels in adults with type 2 diabetes mellitus. It is usually prescribed along with other diabetes medicines to achieve adequate blood sugar control. It also prevents serious complications of diabetes like kidney damage and blindness.
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General Information

The content is shown in English
Repa X1 Tablet image
Repa X1 Tablet image

Product introduction

Repa X1 Tablet is normally prescribed when diet and exercise alone or other medicines have not been enough to control your blood sugar level. It works best when taken before meals. The dose will depend on your condition, and blood sugar levels, but you should take it as advised by your doctor.

Take Repa X1 Tablet regularly, at the same time each day, to get the most benefit and you should not stop unless your doctor recommends it. It is controlling your blood sugar levels and helping to prevent serious complications in the future. It is important to stay on the diet and exercise program recommended by your doctor while taking this medicine. Your lifestyle plays a big part in controlling diabetes.

The most common side effects of this medicine is hypoglycemia (low blood sugar levels). You can carry sugar or glucose candy to control low blood sugar levels. Other common side effects that may be seen while taking this medicine include abdominal pain, inflammation of sinus, joint pain, back pain, nausea, and diarrhea. Contact your doctor if the side effects worry you or if they do not go away.

Before taking this medicine, let your doctor know if you have ever had kidney disease, heart or pancreas problems, or if you drink a lot of alcohol. Pregnant or breastfeeding women should also consult their doctor before taking it. Some other medicines you are taking may interfere with it so make sure your doctor knows about all the other medicines you are taking. You may need regular tests such as kidney function and blood glucose levels to check that the medicine is working properly.

Benefits of Repa X Tablet

Treatment of Type 2 diabetes mellitus
Type 2 diabetes happens when the body cannot use insulin properly or does not make enough of it, leading to high blood sugar levels. Repa X1 Tablet helps lower blood sugar by stimulating the pancreas to release more insulin after meals. This improves blood sugar control and reduces the risk of diabetes-related complications.

Side effects of Repa X Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Repa X
  • Hypoglycemia (low blood glucose level)
  • Abdominal pain
  • Nausea
  • Sinus inflammation
  • Back pain
  • Upper respiratory tract infection
  • Headache
  • Diarrhea
  • Joint pain

How to use Repa X Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Repa X1 Tablet is to be taken on an empty stomach.

How Repa X Tablet works

Repa X1 Tablet is an anti-diabetic medication. It increases the amount of insulin released by the pancreas which prevents blood glucose from rising very high after meals.

Quick tips

  • For best results, take Repa X1 Tablet 15 to 30 minutes before a meal.
  • You should continue to exercise regularly, eat a healthy diet, and take your other diabetes medicines along with Repa X1 Tablet
  • It may cause dizziness. Do not drive or do anything that requires mental focus until you know how  Repa X1 Tablet affects you.
  • It may cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal.
  • Always carry some sugary food or fruit juice with you in case you experience hypoglycemic symptoms such as cold sweats, cool pale skin, tremor, and anxiety.
  • Monitor your blood sugar levels regularly while you are taking this medicine.
  • Inform your doctor if you are pregnant, planning pregnancy or breastfeeding. 

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Repa X1 Tablet. Please consult your doctor.
Pregnancy

Pregnancy

SAFE IF PRESCRIBED
Repa X1 Tablet is generally considered safe to use during pregnancy. Animal studies do not indicate harmful effects. However, there are limited human studies.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Information regarding the use of Repa X1 Tablet during breastfeeding is not available. Please consult your doctor.
Driving

Driving

CAUTION
Repa X1 Tablet may affect your driving ability if your blood sugar becomes too low or too high. Monitor your blood glucose and avoid driving if affected.
Kidney

Kidney

CAUTION
Repa X1 Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Liver

Liver

CAUTION
Repa X1 Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.
Use of Repa X1 Tablet is not recommended in patients with severe liver disease.

Interaction with drugs

Taking Repa X with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Life-threatening

Gemfibrozil (Oral Route)

Do not consume Repaglinide with Gemfibrozil. Gemfibrozil may raise blood levels of Repaglinide.
Severe

Disopyramide (Oral Route)

If concurrent use is essential, watch out for symptoms such as confusion, headache, nausea, dizziness or faintness and consult your doctor if you experience them.
Moderate

Mifepristone (Oral Route)

Watch out for symptoms of Repaglinide side effects such as headache, nausea, dizziness or weakness and consult your doctor if you experience them. Mifepristone may raise blood levels of Repaglinide.
Moderate

Clopidogrel (Oral Route)

Do not consume Clopidogrel with Repaglinide. If concurrent use is essential, your doctor may monitor your blood glucose levels frequently and adjust the dose of Repaglinide as per the observations. Clopidogrel may raise blood levels of Repaglinide.
Moderate

Asparaginase (Injection Route)

Your doctor may monitor your diabetic control closely and adjust the doses as per the observations.

Frequently asked questions

Repa X1 Tablet starts working 30 minutes after it has been taken. After you take Repa X1 Tablet, the insulin levels increase causing a decrease in the blood sugar levels. The effect usually lasts for 4 hours.
No, you should avoid alcohol while taking Repa X1 Tablet since alcohol interferes with the working of Repa X1 Tablet. You may experience signs and symptoms of low blood sugar levels which include weakness, shakiness, cold sweat, cool pale skin, rapid heartbeat, tremors, extreme hunger, dizziness, headache, and anxiety.
Yes, it can be taken with other antidiabetic drugs but according to your doctor’s advice. But since all these drugs lower blood sugar levels, regular monitoring of blood sugar levels is recommended.
No, you should not breastfeed your baby because if Repa X1 Tablet passes in breast milk, your baby may experience low blood sugar levels which is harmful to your baby. Ask your doctor for advice.
You should inform your doctor and take his advice. If you cannot avoid using clopidogrel with Repa X1 Tablet, take 0.5 mg Repa X1 Tablet before each meal. The total daily dose should not be more than 4 mg. Monitor your blood sugar levels more frequently.

Fact Box

Chemical Class

Phenylpiperidines

Habit Forming

No

Therapeutic Class

ANTI DIABETIC

Action Class

Meglitinides (Insulin Secretagogues)

References

  1. Powers AC, D’Alessio D. Endocrine Pancreas and Pharmacotherapy of Diabetes Mellitus and Hypoglycemia. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1257.
  2. Nolte MS. Pancreatic hormones and antidiabetic drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 740-41.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1206-207.
  4. Repaglinide [Product Monograph]. Ontario, Canada: Novo Nordisk Canada Inc.; 2015. [Accessed 4 Oct. 2021] (online) Available from:
  5. DailyMed. Repaglinide [Prescription Drug Label]. [Accessed 4 Oct. 2021] (online) Available from:
  6. Repaglinide [Summary of Product Characteristics]. Debrecen, Hungary: Teva Pharmaceutical Works Private Limited Company; 2014. [Accessed 4 Oct. 2021] (online) Available from:
  7. Milner Z, Akhondi H. Repaglinide. [Updated 2021 Jul 10]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2021 Jan. Available from:
  8. Repaglinide [Prescribing Information]. Princeton, NJ: Macleods Pharma USA, INC; 2023. [Accessed 25 Jul. 2023] (online) Available from:
  9. Repaglinide [Prescribing Information]. Saddle Brook, NJ: Rising Pharma Holdings, Inc.; 2024. [Accessed 19 Jan. 2026] (online). Available from:
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: AAR ESS Remedies Pvt Ltd
Address: Aar Ess Remedies Private Limited, C-28, Sector-65, Noida-201301, Uttar Pradesh, India

Vendor Details

Country of origin: India
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