Pyriphen 250mg Dry Syrup

Paracetamol (250mg/5ml)

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Pyriphen 250mg Dry Syrup is a medicine that helps to ease pain and bring down a high body temperature (fever). In children, it treats conditions like headache, toothache, body aches, fever, and the common cold.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 02 Aug 2026 | 01:01 AM (IST)

MRP ₹42.19

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General Information

Storage

Store below 30°C

The content is shown in English

Your child’s medicine at a glance

Pyriphen 250mg Dry Syrup is given orally, preferably at a fixed time every day. Though this medicine can be taken with or without food, it is best given after food, as Pyriphen 250mg Dry Syrup can irritate the inner lining of an empty stomach. The dose and duration will depend upon your child’s age, body weight, and severity of the infection, so stick to the dose, time, and way prescribed by your child’s doctor. If your child vomits within 30 minutes of taking the medicine, let the child calm down and repeat the same dose. Redosing is not recommended if your child experiences any allergic reaction within 30 minutes after taking a dose.

Do not give your child Pyriphen 250mg Dry Syrup along with other medicines (many cold and flu medicines and other painkillers) that contain paracetamol, as this may result in overdosing and cause dangerous side effects such as hepatotoxicity (liver damage). Always check the ingredients of any other medicines before giving them to your child in combination with this medicine.

Generally, Pyriphen 250mg Dry Syrup is well-tolerated by the children. However, temporary side effects such as indigestion, nausea, and vomiting may occur in some children. Consult your doctor in case these episodes become bothersome for your child.

Pyriphen 250mg Dry Syrup is often considered safe and effective, but may not be suitable for everybody. Inform your doctor if your child is undergoing treatment for any blood-related disorder, is allergic to any medicinal compound, or has any birth defects, liver impairment, or kidney dysfunction. This will help your child’s doctor evaluate the dose and suitability of this medicine in a better way.

Uses of Pyriphen 250mg Dry Syrup in children

Benefits of Pyriphen 250mg Dry Syrup for your child

Pain relief
Pyriphen 250mg Dry Syrup is a common painkiller used to treat aches and pains. It works by blocking chemical messengers in the brain that tell us we have pain. It is effective in relieving pain caused by headache, migraine, nerve pain, toothache, sore throat, period (menstrual) pains, arthritis, and muscle aches. This medicine is very widely used and very rarely causes side effects if taken at the right dosage. Take it as it is prescribed to get the most benefit. Do not take more or for longer than needed as that can be dangerous. In general, you should take the lowest dose that works, for the shortest possible time. It is also the first choice of painkiller during pregnancy or breastfeeding.

Treatment of Fever
Pyriphen 250mg Dry Syrup is also used to reduce a high temperature (fever). It works by blocking the release of certain chemical messengers that cause fever. It may be prescribed alone or in combination with another medicine. You should take it regularly as advised by your doctor.

Side effects of Pyriphen 250mg Dry Syrup in children

Pyriphen 250mg Dry Syrup does not pose serious side effects and is well-tolerated by children. In case the side effects do occur, they’re likely to subside once the body adapts to the medicine. Consult your child’s doctor if these side effects persist or bother your child. The most common side effects include-

Common side effects of Pyriphen

Indigestion
Vomiting
Stomach pain
Nausea
Limited data available

How can I give Pyriphen 250mg Dry Syrup to my child?

Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Dissolve the powder in sterile water. Shake well and use. Pyriphen 250mg Dry Syrup may be taken with or without food.

How Pyriphen Dry Syrup works

Pyriphen 250mg Dry Syrup works as a pain reliever (analgesic) and fever reducer (antipyretic) by blocking the production of certain chemicals in the brain called prostaglandins. These chemicals are involved in causing pain and fever, so by reducing their levels, Pyriphen 250mg Dry Syrup helps ease pain and discomfort and lowers body temperature.

Quick tips

Give Pyriphen 250mg Dry Syrup to your child with food or milk to prevent an upset stomach.
Never give any other medicine formulation containing paracetamol along with this medicine, as that may lead to serious side effects.
Inform the doctor if your child has liver disease, as the dose may need to be adjusted.
If Pyriphen 250mg Dry Syrup does not seem to be helping your child, contact your doctor for advice. Do not give extra doses.

Safety advice

Kidney

CAUTION

Pyriphen 250mg Dry Syrup should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.

Liver

UNSAFE

Pyriphen 250mg Dry Syrup is unsafe to use in patients with liver disease and should be avoided.
However, the use of Pyriphen 250mg Dry Syrup is not recommended in children with severe liver disease and active liver disease.

Interaction with drugs

Taking Pyriphen with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Moderate

Lenalidomide (Oral Route)

Your doctor may monitor your liver function frequently.

Moderate

Bemiparin (Injection Route)

If concurrent use is essential, watch out for symptoms such as fatigue, nausea, loss of appetite, dark urine or jaundice and consult your doctor if you experience them. They may adjust the doses as per the observations.

Moderate

Certoparin (Injection Route)

Moderate

Dalteparin (Injection Route)

Moderate

Enoxaparin (Injection Route)

Frequently asked questions

How much Pyriphen 250mg Dry Syrup should I give to my child?

Always follow your doctor's instructions regarding how much of the medicine to give and how often to give it. This depends on the strength of the medicine and the age of your child. You may also check the label or the leaflet inside the packaging for directions before use.

When will my child’s condition improve after taking Pyriphen 250mg Dry Syrup?

Pyriphen 250mg Dry Syrup usually starts working within 30 to 60 minutes of intake and shows its peak effect within 3 to 4 hours. Your child may start to feel better after a few doses. In case the pain or fever persists longer, consult your child’s doctor immediately.

Can I give Pyriphen 250mg Dry Syrup to my child for low-grade fever?

You can give this medicine if your child has a temperature of 38.3°C (101°F) or higher. But you must always try to speak to your child’s doctor first.

My child’s fever is persistent even after taking Pyriphen 250mg Dry Syrup. What should I do?

If the fever doesn't come down after the initial few doses, the cause might be an infection (virus or bacteria). It is advised to consult your child’s doctor for specific treatment.

How much of Pyriphen 250mg Dry Syrup is considered as an overdose?

Unless instructed by your doctor, your child should take a normal, balanced diet while continuing this medicine, as a lack of nutrition can put your child at risk of developing medication toxicity.

Where should I store this medicine?

Keep this medicine at room temperature in a dry place beyond the reach of children.

In what conditions Pyriphen 250mg Dry Syrup must be given with caution?

It is advised to use Pyriphen 250mg Dry Syrup with caution if the child has malnutrition, G6PD deficiency, liver disease, or any medical allergy. So, do not hesitate to share your child’s complete medical history with the doctor, as that will help the doctor decide whether the medicine is safe for your child or not.

Can I give Pyriphen 250mg Dry Syrup on a routine basis when my child is taking a vaccine?

Pyriphen 250mg Dry Syrup usually does not interfere with the ingredients in vaccines or cause a bad reaction in a child who has just been vaccinated. However, it is best if you let your child recover from the ongoing illness and finish the course of the medicine. As soon as your child feels better, the vaccine can and should be given.

Does Pyriphen 250mg Dry Syrup make babies sleepy?

No, Pyriphen 250mg Dry Syrup does not make babies sleepy. It is a pain-relieving medicine that is also used to control high fever.

Fact Box

Chemical Class

1- hydroxy- 2- unsubstituted benzenoids

Habit Forming

Therapeutic Class

PAIN ANALGESICS

Action Class

Analgesic & Antipyretic-PCM

Related lab tests

Complete Blood Count

References

Paracetamol [EMC Patient Leaflet]. Leeds, UK: Rosemont Pharmaceuticals Limited; 2019. [Accessed 26 Dec. 2020] (online) Available from:
Aabideen K, Moulton LS, Sills J. Accidental staggered paracetamol overdose: An interesting case report. J Pharmacol Pharmacother. 2011;2(3):189-190. [Accessed 26 Dec. 2020] (online) Available from:
Grosser T, Smyth E, FitzGerald GA. Anti-Inflammatory, Antipyretic, and Analgesic Agents; Pharmacotherapy of Gout. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 982-84.
Paracetamol [Product Information]. Worli, Mumbai: GlaxoSmithKline Pharmaceuticals Limited; 2024. [Accessed 25 Jul. 2024] (online) Available from:
Acetaminophen [Prescribing Information]. Markham, Ontario: McNeil Consumer Healthcare; 2021. [Accessed 09 May 2025] (online) Available from:

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Novogen Captab
Address: SCO, No. 178, 1st Floor, Sector 39 D, Chandigarh-160036, India

Vendor Details

Country of origin: India

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Pyriphen 250mg Dry Syrup

Pyriphen 250mg Dry Syrup

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General Information

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Salt Synonyms

Marketer

Storage

Your child’s medicine at a glance

Uses of Pyriphen 250mg Dry Syrup in children

Benefits of Pyriphen 250mg Dry Syrup for your child

Side effects of Pyriphen 250mg Dry Syrup in children

How can I give Pyriphen 250mg Dry Syrup to my child?

How Pyriphen Dry Syrup works

Quick tips

Safety advice

Kidney

Liver

Interaction with drugs

Lenalidomide (Oral Route)

Bemiparin (Injection Route)

Certoparin (Injection Route)

Dalteparin (Injection Route)

Enoxaparin (Injection Route)

Frequently asked questions

How much Pyriphen 250mg Dry Syrup should I give to my child?

When will my child’s condition improve after taking Pyriphen 250mg Dry Syrup?

Can I give Pyriphen 250mg Dry Syrup to my child for low-grade fever?

My child’s fever is persistent even after taking Pyriphen 250mg Dry Syrup. What should I do?

How much of Pyriphen 250mg Dry Syrup is considered as an overdose?

Where should I store this medicine?

In what conditions Pyriphen 250mg Dry Syrup must be given with caution?

Can I give Pyriphen 250mg Dry Syrup on a routine basis when my child is taking a vaccine?

Does Pyriphen 250mg Dry Syrup make babies sleepy?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Complete Blood Count

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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