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Advanced International Certification Course in Diabetes, Cardio-diabetes, Thyroid and Endocrine Disorders, BDS
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Writing in Medical Sciences, Medical Writing, Advanced PG Diploma in Clinical Research
Last updated on:
15 Mar 2019 | 05:10 PM (IST)
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Uses of Pyrigesic Tablet

Pyrigesic 650 Tablet is used for pain relief and fever. It is used to relieve pain in conditions like headache, joint pain, muscle pain or dental pain.

Pyrigesic Tablet side effects

No common side effects seen

How to use Pyrigesic Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Pyrigesic 650 Tablet is to be taken with food.

How Pyrigesic Tablet works

Pyrigesic 650 Tablet is an analgesic (pain reliever) and anti-pyretic (fever reducer). It works by blocking the release of certain chemical messengers that cause pain and fever.

Pyrigesic Tablet related warnings

Taking Paracetamol/Acetaminophen with alcohol can cause liver damage.
Pyrigesic 650 Tablet is safe to use during pregnancy.
Adequate and well-controlled human studies have shown low or no risk.
Pyrigesic 650 Tablet is safe to use during lactation. Human studies have shown that either the drug does not pass into the breastmilk in significant amount or is not expected to cause toxicity to the baby.
Pyrigesic 650 Tablet does not usually affect your ability to drive.
Pyrigesic 650 Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Pyrigesic 650 Tablet may be needed. Please consult your doctor.
However, Pyrigesic 650 Tablet contains paracetamol which is considered the safest painkiller for kidney disease patients.
Pyrigesic 650 Tablet should be used with caution in patients with liver disease. Dose adjustment of Pyrigesic 650 Tablet may be needed. Please consult your doctor.
However, the use of Pyrigesic 650 Tablet is not recommended in patients with severe liver disease and active liver disease.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Pyrigesic 650 Tablet
Dolo 650mg Tablet
Micro Labs Ltd
same price
Calpol 650mg Tablet
Glaxo SmithKline Pharmaceuticals Ltd
same price
Xykaa Rapid 650mg Tablet
Troikaa Pharmaceuticals Ltd
same price
Fepanil 650mg Tablet
Veritaz Healthcare Ltd
same price
P 650 Tablet
Apex Laboratories Pvt Ltd
same price

Expert Advice

  • Good for pain relief and fever but not effective in joint pain due to poor anti-inflammatory action.
  • Starts working within one hour. Wait for at least 4 hours before taking the next dose.
  • Present in many over-the-counter (OTC) and prescription medicines. Avoid taking more than one paracetamol product at a time to prevent overdose. Doses >4 g/day (2 g in alcoholics) may cause liver, kidney or heart problems.
  • Discontinue Pyrigesic 650 Tablet and inform your doctor immediately if rash occurs.
  • For children, measure the doses of liquid Pyrigesic 650 Tablet using the measuring cup instead of a teaspoon to avoid under or over-dosage.
  • Avoid excess alcohol intake (>3 glasses/day) when taking Pyrigesic 650 Tablet as it may cause liver damage.

Interaction with Drugs

Taking Pyrigesic with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Nimsun, Abinim, Nimulis
Brand(s): Clorocin, Vecol, Sitamycetine
Brand(s): Metromide, Vomitrac

Patient Concerns

Questions Related to Pyrigesic

I am feeling pain and sound in my knee joint at the time of sitting on floor. I have suffered by Chikungunya fever about 7 months back. I am a patient of sugar from last 10 years and taking Glimestar M1. Can you please suggest some medicine to resolve my problem.
Dr. Akshat Goel
Bone & Joint Specialist
Cap Altraday once or twice daily for pain reliefGet a Digital x-ray done of both knees AP-view in standing position and share it
Very severe pain in legs. From upper thighs upto knees. I took one Combiflame yesterday morning and one yesterday evening with oil massage but relief for just short period Its so un bearable again I feel like crying. No fever as took one Voveron sr100 at 4.30 am but No respite.I am really worried pls advice
Dr. Akshat Goel
Bone & Joint Specialist
Do Hot Fomentation and apply Dynapar QPS spray and take Tab Myospas-D thrice daily and Tab Flotrip-forte thrice daily and Cap Nurokind-Gold twice daily for 5 days.Avoid forward bending and Avoid lifting heavy weightIn extreme pain take one tablet of NAXDOM-500 for immediate pain relief
Do you have any questions related to Pyrigesic 650 Tablet?

User Feedback


Q. How long does Pyrigesic takes to work?

Pyrigesic takes around 30-45 min to start working and show its effects.

Q. How long does Pyrigesic stay in my body?

Usually, Pyrigesic stay for 5-6 hours in tthe body. However, this duration can vary from person to person.

Q. If I suddenly stop taking Pyrigesic, can this cause any withdrawal symptom?

No, Pyrigesic does not cause any withdrawal symptoms even if you suddenly stop taking this medicine.

Q. How much Pyrigesic can you take in a day?

In adults, the total dose of Pyrigesic should not exceed 4g per day. In children, the maximum dose should not exceed 60mg/kg in a day.

Q. What is the recommended dose of Pyrigesic?

In adults, the usual dose is 1-2 tablets i.e 500mg or 650mg. The minimum dosing interval should be of 4 hours between the doses. The total dose should not exceed 4g per day.

Q. Can the use of Pyrigesic make me feel sleepy?

No, Pyrigesic does not cause sleepiness.
Related Lab Tests
Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
Manufacturer/Marketer Address
A licensed pharmacy from your nearest location will deliver Pyrigesic 650 Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your prescription and the availability of this medicine.
10 tablets in 1 strip
Best Price ₹15.5
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